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138篇 您的检索式:作者名="Mayne P"
    题名 作者 年代 出处 被引量
1miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus显示文摘AIM: To investigate miR-200 family expression in Barrett's epithelium, gastric and duodenal epithelia, and esophageal adenocarcinoma. METHODS: Real-time reverse transcriptase-polymerase chain reaction was used to measure miR-200, ZEB1 and ZEB2 expression. Ingenuity Pathway Analysis of miR-200 targets was used to predict biological outcomes. RESULTS: Barrett's epithelium expressed lower levels of miR-141 and miR-200c than did gastric and duodenal epithelia (P < 0.001). In silico analysis indicated roles for the miR-200 family in molecular pathways that distinguish Barrett's epithelium from gastric and duodenalepithelia, and which control apoptosis and proliferation. All miR-200 members were downregulated in adenocarcinoma (P < 0.02), and miR-200c expression was also downregulated in non-invasive epithelium adjacent to adenocarcinoma (P < 0.02). The expression of all miR-200 members was lower in Barrett's epithelium derived high-grade dysplastic cell lines than in a cell line derived from benign Barrett's epithelium. We observed signif icant inverse correlations between miR-200 family expression and ZEB1 and ZEB2 expression in Barrett's epithelium and esophageal adenocarcinoma (P < 0.05). CONCLUSION: miR-200 expression might contribute to the anti-apoptotic and proliferative phenotype of Barrett's epithelium and regulate key neoplastic processes in this epithelium.Cameron M Smith David I Watson Mary P Leong George C Mayne Michael Z Michael Bas PL Wijnhoven Damian J Hussey 2011World Journal of Gastroenterology2011,17,8:13
2Development of a European herbage growth model(the EU Grazemore project)显示文摘Barrett P D Mayne A S 2004Grassland Science in Europe2004,9,:1
3Ground response to dynamic compaction显示文摘Mayne P W 1984Journal of Geotechnical Engineering ASCE1984,110,6:1
4Statistical relationships between piezocone measurements and stress history of clays显示文摘CHEN B S Y MAYNE P W 1996Canadian Geotechnical Journal1996,33,:1
5GrazeGro: a European herbage growth model to predict pasture production in perennial ryegrass swards for decision support 显示文摘Barrett P D Laidlaw A S Mayne C S 2005European Journal of Agronomy2005,1,:1
6Impact stress during dynamic compaction显示文摘Mayne P Q Jones J S 1983Journal of Geotechnical Engineering ASCE1983,109,10:1
7Cam-clay predictions of undrained strength显示文摘MAYNE P W 1980Journal of the Geotechnicial Engineering Division1980,11,:1
8Impact stress during dynamiccompaction显示文摘Mayne P Q Jones J S 1983Journal of Geotechnical Engineering1983,109,10:1
9Characterization of a novel leucine-rich repeat protein antigen from Group B streptococci that elicits protective immunity显示文摘Seepersaud R Hanniffy S B Mayne P 2005Infection and Immunity2005,73,3:1
10Determining preconsolidation stress and penetration pore pressures from DTM contact pressures 显示文摘Mayne P W 1987Geotechnical Testing Journal1987,10,1:1
11Cam-clay predictions of undrained strength 显示文摘 1980Journal of Geotechnical engineering Division1980,106,11:1
12Serological screening tests for syphilis in pregnancy:results of a five year study (1983-87)in the Oxford region显示文摘Bowel1 P Mayne K Puckett A 1989J Clin Pathol1989,42,12:1
13Min-max feedback model predictive control for constrained linear systems 显示文摘SCOKAERT P O M MAYNE D Q 1998IEEE Transactions on Automatic Control1998,43,8:1
14K0-OCR relationships in soil显示文摘Mayne P W and Kulhawy F H 1982Journal of the Geotechnical Engineering Division ASCE June1982,1982,:1
15Constrained Model Predictive Control: Stability and Optimality显示文摘Mayne D Q RawlingsJ B Rao C V Scokaert P 0 M 2000Automatica2000,36,6:1
16Constrained model predictive control:Stability and optimality显示文摘Mayne D Q Rawlings J B Rao C V Scokaert P O M 0,,06:1
17Constrained Model Predictive Control: Stability and Optimality 显示文摘D Q Mayne J B Rawlings C V Rao & P O M Scokaert 2000Automatica2000,36,:1
18Discussion of 'interpretation of overconsolidation ratio from in situ tests in recent clay deposits in Singapore and Malaysia显示文摘MAYNE P W 1992Canadian Geotechnical Journal1992,29,1:1
19Impact Stressed During Dynamic Compaction显示文摘 Jones J S 1983ASCE Journal of Geotechnical Engineering1983,109,10:1
20Cam-clay predictions of undrained strength 显示文摘Mayne P W 1980Journal of Geotechnical Engineering Divi- sion1980,106,11:1
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