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| 1 | Celiac disease:Management of persistent symptoms in patients on a gluten-free diet显示文摘AIM:To investigate all patients referred to our center with non-responsive celiac disease (NRCD),to establish a cause for their continued symptoms.METHODS:We assessed all patients referred to our center with non-responsive celiac disease over an 18-mo period.These individuals were investigated to establish the eitiology of their continued symptoms.The patients were first seen in clinic where a thorough history and examination were performed with routine blood work including tissue transglutaminase antibody measurement.They were also referred to a specialist gastroenterology dietician to try to identift any lapses in the diet and sources of hidden gluten ingestion.A repeat small intestinal biopsy was also performed and compared to biopsies from the referring hospital where possible.Colonoscopy,lactulose hydrogen breath testing,pancreolauryl testing and computed tomography scan of the abdomen were undertaken if the symptoms persisted.Their clinical progress was followed over a minimum of 2 years.RESULTS:One hundred and twelve consecutive patients were referred with NRCD.Twelve were found not to have celiac disease (CD).Of the remaining 100 patients,45% were not adequately adhering to a strict gluten-free diet,with 24 (53%) found to be inadvertently ingesting gluten,and 21 (47%) admitting noncompliance.Microscopic colitis was diagnosed in 12% and small bowel bacterial overgrowth in 9%.Refractory CD was diagnosed in 9%.Three of these were diagnosed with intestinal lymphoma.After 2 years,78 patients remained well,eight had continuing symptoms,and four had died.CONCLUSION:In individuals with NRCD,a remediable cause can be found in 90%:with continued gluten ingestion as the leading cause.We propose an algorithm for investigation. | David H Dewar Suzanne C Donnelly Simon D McLaughlin Matthew W Johnson H Julia Ellis Paul J Ciclitira | 2012 | World Journal of Gastroenterology2012，18，12： | 2 |
| 2 | High diversity andwidespread occurrence of mitotic spore mats in ectomycorrhizalPezizales显示文摘 | Healy R A Smith M E Bonito G M Pfister D H Ge Z W Guevara G G ’ Williams G Stafford K Kumar L Lee T HobartC Trappe J Vilgalys R McLaughlin D J | 2013 | Molecular Ecology2013，22，： | 1 |
| 3 | The estimation of distances between specific backbone-labeled sites in DNA using fluorescence resonance energy transfer显示文摘 | Ozaki H Mclaughlin L W | 1992 | Nucleic Acids Res1992，20，： | 1 |
| 4 | The estimation of distances between specific backbone-labeled sites in DNA using fluo- rescence resonance energy transfer显示文摘 | Qzaki H McLaughlin L W | 1992 | Nucleic Acids Res1992，20，19： | 1 |
| 5 | Job performance deficits due to depression 显示文摘 | Adler D A McLaughlin T J Rogers W H | 2006 | Am J Psychiatry2006，163，： | 1 |
| 6 | The estimation of distances between specific backbone-labeled sites in DNA using fluorescence resonance energy transfer显示文摘 | OZAKI H MCLAUGHLIN L W | 1992 | Nucleic Acids Res1992，20，： | 1 |
| 7 | Cancerrates among drinkers of black tea 显示文摘 | BLOT W J MCLAUGHLIN J K CHOW W H | 1997 | Critical Reviews in Food Science and Nutrition1997，37，8： | 1 |
| 8 | Stimulation of the weak ATPase activity of human hsp90 by a client protein 显示文摘 | MCLAUGHLIN S H SMITH H W JACKSON S E | 2002 | J Mol Biol2002，315，4： | 1 |
| 9 | Broadband MIMO-OFDM wireless communication显示文摘 | STUBER G L BARRV J H MCLAUGHLIN S W | 2004 | Proceedings of the IEEE2004，92，2： | 1 |
| 10 | Astatination via electrophilic destannylation显示文摘 | Milius R A Mclaughlin W H Lambrecht R M | 1986 | Appl Radiat Isot1986，37，： | 1 |
| 11 | A semi- analytical PDF of downlink SINR for femtocell networks显示文摘 | SUNG K W HAAS H and MCLAUGHLIN S | 2010 | EURASIP Journal on Wireless Communications and Networking2010，2010，5： | 1 |
| 12 | The gamma-ray response of radiochromic dye films at different absorbed dose rates显示文摘 | MCLAUGHLIN W L HUMPHREYS J C LE- VINE H | 1981 | Radiat Phys Chem1981，18，： | 1 |
| 13 | Approximation of bounded sets显示文摘 | Frcilich J H Mclaughlin H W | 1982 | J Approx Theory1982，34，2： | 1 |
| 14 | The estimation of distances between specific backbone-labeled sites in DNA using fluorescence resonance energy transfer 显示文摘 | Qzaki H McLaughlin L W | 1992 | Nucleic Acids Res1992，20，19： | 1 |
| 15 | Biochemical and structural studies of the interaction of Cdc37 with Hsp90显示文摘 | Zhang W Hirshberg M McLaughlin S H | 2004 | J Mol Biol2004，340，： | 1 |
| 16 | Rate-Compatible Puncturing of Low-Density Parity-Check Codes显示文摘 | Jeongseok H Jaehong K McLaughlin S W | 2004 | IEEE Trans on Information Theory2004，50，11： | 1 |
| 17 | Describing the surface:algorithms for geometric modeling显示文摘 | MCLAUGHLIN H W | 1986 | Computers in Mechanical Engineering1986，5，3： | 1 |
| 18 | Results of 3D conformal radiotherapy in the treatment of localized prostate cancer显示文摘 | Fukunaga-Johnson N Sandier H M McLaughlin P W | 1997 | Int J Radiat Oncol Biol Phys1997，38，2： | 1 |
| 19 | The estimation of distancesbetween specific backbone-labeled sites in DNA usingfluorescence resonance energy transfer显示文摘 | Ozaki H McLaughlin L W | 1992 | Nucleic AcidsRes1992，20，19： | 1 |
| 20 | Prognosis of pulmonary ayterial hypertension :ACCP evidence-based clinical practice guidelines显示文摘 | McLaughlin V V Presberg K W Doyle R L Abman S H McCrory D C Fortin T | 2004 | Chest2004，126，1： | 1 |
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