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| 1 | Effect of Low Level Subchronic Microwave Radiation on Rat Brain显示文摘Objective The present study was designed to investigate the effects of subchronic low level microwave radiation(MWR) on cognitive function,heat shock protein 70(HSP70) level and DNA damage in brain of Fischer rats.Methods Experiments were performed on male Fischer rats exposed to microwave radiation for 90 days at three different frequencies: 900,1800,and 2450 MHz.Animals were divided into 4 groups: Group I: Sham exposed,Group II: animals exposed to microwave radiation at 900 MHz and specific absorption rate(SAR) 5.953 × 10-4 W/kg,Group III: animals exposed to 1800 MHz at SAR 5.835 × 10-4 W/kg and Group IV: animals exposed to 2450 MHz at SAR 6.672 × 10-4 W/kg.All the animals were tested for cognitive function using elevated plus maze and Morris water maze at the end of the exposure period and subsequently sacrificed to collect brain tissues.HSP70 levels were estimated by ELISA and DNA damage was assessed using alkaline comet assay.Results Microwave exposure at 900-2450 MHz with SAR values as mentioned above lead to decline in cognitive function,increase in HSP70 level and DNA damage in brain.Conclusion The results of the present study suggest that low level microwave exposure at frequencies 900,1800,and 2450 MHz may lead to hazardous effects on brain. | Pravin Suryakantrao Deshmukh Kanu Megha Namita Nasare Basu Dev Banerjee Rafat Sultana Ahmed Mahesh Pandurang Abegaonkar Ashok Kumar Tripathi Pramod Kumari Mediratta | 2016 | Biomedical and Environmental Sciences2016，29，12： | 4 |
| 2 | Possible mechanism of anticonvulsant effect of ketamine in mice显示文摘 | Manocha A Sharma KK Mediratta PK | 2001 | Indian J Exp Biol2001，39，10： | 1 |
| 3 | Studies on the anticonvulsant effect of U50488H on maximal electroshock seizure in mice显示文摘 | MANOCHA A MEDIRATTA P K SHARMA K K | 2003 | Pharmacol Biochem Behav2003，76，1： | 1 |
| 4 | Preoperative red cell distribution width in patients undergoing pulmonary resections for non-small-cell lung cancer 显示文摘 | Warwick R Mediratta N Shackcloth M | 2014 | Eur J Cardiothorac Surg2014，45，1： | 1 |
| 5 | Insulin resistance in systemic hypertension: pharmacotherapeutic implications 显示文摘 | Mediratta S Fozailoff A Frishman WH | 1995 | J Clin Pharmacol1995，35，10： | 1 |
| 6 | Validation of EuroSCORE 11 in a modern cohort of patients undergoing cardiac surgery 显示文摘 | Chalmers J Pullan M Fabri B McShane J Shaw M Mediratta N | 2013 | Eur J Cardiothorac Surg2013，43，： | 1 |
| 7 | Possible mechanism of anticonvulsant effect of ketamine in mice 显示文摘 | Manocha A Sharma KK Mediratta PK | 2001 | Indian J Exp Biol2001，39，10： | 1 |
| 8 | Influence of austenitisation temperature on the structure and properties of weather resistant steels显示文摘 | Prasad S N Mediratta S R Sarma D S | 2003 | Materials Science and Engineering2003，358，： | 1 |
| 9 | Potentiation of analgesia and reversal of tolerance to morphine by calcium channel blockers显示文摘 | Verma V Mediratta PK Sharma KK | 2001 | Indian J Exp Biol2001，39，7： | 1 |
| 10 | The anticonvul ant effect of pentazocine against maximal electroshock seizure in mice显示文摘 | Anshu manocha Sharma KK Mediratta TK | 1997 | Indian Journal of Pharmacology1997，29，3： | 1 |
| 11 | Evaluation of the role of melatonin in formalin-induced pain response in mice显示文摘 | Ray M Mediratta PK Mahajan P | 2004 | Indian J Med Sci2004，58，3： | 1 |
| 12 | Evaluation of the role of melatonin in formalin indueed pain response in miee显示文摘 | Ray M Mediratta PK Mahajan P | 2004 | Indian J Med Res2004，58，3： | 1 |
| 13 | Role of kappa- and delta-opioid receptors in the antinociceptive effect of oxytocin in formalin-induced pain response in mice 显示文摘 | Reeta K Mediratta PK Rathi N | 2006 | Regul Pept2006，135，12： | 1 |
| 14 | Effect of L-arginine on restraint stress induced modulation of immune responses in rats and mice显示文摘 | Sharma KK Mediratta PK Reeta KH | 2004 | Pharmacol Res2004，49，5： | 1 |
| 15 | Effect of lamotrigine, oxcarbazepine and topiramate on cognitive functions and oxidative stress in PTZ-kindled mice 显示文摘 | Agarwal NB Agarwal NK Mediratta PK | 2011 | Seizure2011，20，3： | 1 |
| 16 | Effect of L-arginine on restraint stress induced modulation of immune responses in rats and mice 显示文摘 | Sharma K K Mediratta P K Reeta K H | 2004 | Pharmacol Res2004，49，5： | 1 |
| 17 | Potentiation of analgesia and reversal of tolerance to morphine by calcium channel blockers显示文摘 | Verma V Mediratta PK Sharma KK | 2001 | Indian J Exp Biol2001，39，7： | 1 |
| 18 | Wedge resection verses lobectomy for stage 1 non-small-cell lung eancer显示文摘 | Warwick R Mediratta N Shackcloth M | 2013 | Asi- an Cardiovasc Thorac Ann2013，21，5： | 1 |
| 19 | Evaluation of immunomodulatory potential of Ocimum sanctum seed oil and its possible mechanism of action显示文摘 | P.K Mediratta K.K Sharma Surender Singh | 2002 | Journal of Ethnopharmacology2002，，1： | 1 |
| 20 | Effect of lamotrigine,Oxcarbazepine and topiramate on cognitive functions and oxidative stress in PTZ-kindled mice显示文摘 | AGARWAL NB AGARWAL NK MEDIRATTA PK | 2011 | Seizure2011，20，3： | 1 |
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