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| 1 | Candidates for liver transplantation with alcoholic liver disease: Psychosocial aspects显示文摘In Europe, 30% to 50% of liver transplantations are currently due to alcoholic liver disease(ALD). In the United States, this percentage is 17.2%. Post-transplantsurvival and other predictors of clinical course do not differ significantly from those in other types of transplanted patients, as long as there is no relapse of drinking. However, 20%-25% of these patients lapse or relapse to heavy drinking post-operatively, which has been associated with an increased risk of liver damage and mortality. It is therefore crucial to design specific selection and follow-up strategies aimed at this particular type of patient. Several good and poor prognosis factors that could help to predict a relapse have been suggested, among them the duration of abstinence, social support, a family history of alcoholism, abuse diagnosis versus alcohol dependence, non-acceptance of diagnosis related to alcohol use, presence of severe mental illness, nonadherence in a broad sense, number of years of alcoholism, and daily quantity of alcohol consumption. In this article, we discuss these and other, more controversial factors in selecting ALD patients for liver transplantation. Abstinence should be the main goal after transplantation in an ALD patient. In this article, we review the several definitions of post-transplant relapse, its monitoring and the psychopharmacological and psychotherapeutic treatment. | Diogo Telles-Correia Inês Mega | 2015 | World Journal of Gastroenterology2015，21，39： | 2 |
| 2 | Prevention of complications after percu- taneous coronary interventions with statins 显示文摘 | Mega S Nusca A Patti G | 2012 | Recenti Prog Med2012，103，1： | 1 |
| 3 | Cytochrome p450 polymorphisms and response to clopidogrel显示文摘 | Mega J L Close S L Wiviott S D | 2009 | N Engl J Med2009，360，21： | 1 |
| 4 | Cytochrome P450 polymorphisms and response to clopidogrel 显示文摘 | MEGA J L CLOSE S L WIVIOTT S D | 2009 | N Engl J Med2009，360，3： | 1 |
| 5 | Cytochrome p- 450 polymorphism and response to clopidogrel 显示文摘 | MEGA J L CLOSE S L WIVIOTr S D | 2009 | N Engl J Med2009，360，4： | 1 |
| 6 | Interaction between cigarette smoking and clinical benefit of clopidogrel 显示文摘 | DESAI N R MEGA J L JIANG S | 2009 | J Am Coll Cardiol2009，53，10： | 1 |
| 7 | Cytochrome P-450 Polymorphisms and Response to Clopidogrel显示文摘 | MEGA J L CLOSE S L WIVIOTT S D | 2009 | N Engl J Med2009，360，： | 1 |
| 8 | Interaction between cigarette smoking and clinical benefit of clopidogrel显示文摘 | Desai NR Mega JL Jiang S | 2009 | J Am Coll Cardio2009，53，15： | 1 |
| 9 | Genetic variants in ABCB 1 and CYP2C 19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITONTIMI 38 trial: a pharmacogenetic analysis显示文摘 | Mega J L Close S L Wiviott S D | 2010 | Lancet2010，376，9749： | 1 |
| 10 | Rivaroxaban in patients with a recent acute coronary syndrome显示文摘 | Mega J L Braunwald E Wiviott S D | 2012 | N Engl J Med2012，366，1： | 1 |
| 11 | Immunohistochemical analysis of nuclear survivin expression in esophageal squamous cell carcinoma 显示文摘 | Mega S Miyamoto M Li L | 2006 | Dis Esophagus2006，19，5： | 1 |
| 12 | Cytochrome p-450 polymorphisms and response to clopidogrel显示文摘 | MEGA J L CLOSE S L WIVIOTT S D | 2009 | N Engl J Med2009，360，4： | 1 |
| 13 | Percutaneous coronary interventions and statin therapy 显示文摘 | Mega S Nusca A Patti G | 2012 | Recenti Prog Med2012，103，1： | 1 |
| 14 | Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial:a pharmacogenetic analysis显示文摘 | MEGA J L CLOSE S L WIVIOTT S D | 2010 | Lancet2010，376，9749： | 1 |
| 15 | Cytochrome p-450 polymorphisms and response to clopidogrel显示文摘 | Mega J L Close S L Wiviott S D | | 0，，04： | 1 |
| 16 | Rivaroxaban versus placebo in patients with acute coronary syndromes (ATLAS ACS-TIMI 46):a randomisad,double-blind,phase Ⅱ trial显示文摘 | Mega JL Braunwald E Mohanavelu S | 2009 | Lancet2009，374，9683： | 1 |
| 17 | Cyclin D1, E2F1 expression levels are associated with characteristics and prognosis of esophageal squamous cell carcinoma显示文摘 | MEGA S MIYAMOTO M EBIHARA Y | 2005 | Dis Esophagus2005，18，： | 1 |
| 18 | Cytochrome P4s0 polymorphisms and response to clopidogrel显示文摘 | MEGA J L CLOSE S L WIVIOTF S D | 2009 | N Engl J Med2009，360，4： | 1 |
| 19 | Cytochrome p -450 polymorphisms and response to clopidogrel 显示文摘 | MEGA J L CLOSE S L WIVIOTT S D | 2009 | N Engl JMed2009，360，4： | 1 |
| 20 | Cyclin D1,E2F1 expression levels are associated with characteristics and prognosis of esophageal squamous cell carcinoma显示文摘 | Mega S Miyamoto M Ebihara Y | 2005 | Dis Esophagus2005，18，2： | 1 |
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