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| 1 | 一种基于G1-变异系数法的井下掘进工作面通风方式优选方法(英文)显示文摘现有的矿山通风决策和优化方法往往是基于单一的主观经验或客观信息,不能将两者很好地结合起来进行考虑。论文提出了一种基于G1-变异系数法的优选方法,利用组合赋权,弥补评价指标单一赋权的缺陷。在实例研究中,建立了合理的评价指标体系,利用评价模型计算得出各备选通风模式的评估值,根据总的评估值来选择最优巷道掘进面通风方式。研究结果表明,该方法能够对掘进面通风方式备选方案进行合理排序,既具有主客观赋权方法的优点,又兼顾了专家的经验和智慧,以及客观条件的新变化。利用该方法进行掘进工作面通风方式分析、评价更为合理和可靠。 | 周智勇 Mehmet KIZIL 陈中伟 陈建宏 | 2018 | Journal of Central South University2018，25，10： | 9 |
| 2 | Increased oxidative damage of sperm and seminal plasma in men with idiopathic infertility is higher in patients with glutathione S-transferase Mu-1 null genotype显示文摘瞄准:检验一种关系是否与自发的不孕从病人在 glutathioneS-transferase Mu-1 (GSTM1 ) 基因多型性和精子和精液的血浆的危险性之间存在到氧化应力。方法:有自发的不孕的 52 个人和 60 个健康的肥沃的人被招募到这研究。GSTM1 基因多型性被聚合酶链反应(PCR ) 和两个决定不肥沃并且我们根据他们的 GSTM1 基因再划分进空的 GSTM1 和 GSTM1 积极的组的控制个人组织。Wecompared 反应的氧种类(ROS ) 产生, malondialdehyde (MDA ) ,蛋白质羰基和谷胱甘肽(GSH ) 集中,和在从关于 GSTM1 遗传型的不肥沃的病人和控制的精液的血浆和精子的谷胱甘肽 S-transferase (GST ) 活动。结果: 显著地,氧化应力和损坏标记的高水平与 GSTM1 积极遗传型与那些相比与 GSTM1 空遗传型在自发的不肥沃的人被发现。在为在自发的不肥沃的题目和肥沃的题目之间的 GSTM1 变体的遗传型分发没有重要差别。有 GSTM1 空遗传型的病人也与 GSTM1 积极遗传型比那些有更低的精子集中。结论:我们的结果建议到氧化应力的精子和精液的血浆的危险性与拥有基因的那些相比在有 GSTM1 空遗传型的自发的不肥沃的人是显著地更大的。因此,在有自发的不孕的病人,, GSTM1 多型性可能是在到氧化损坏的精子的危险性的变化的重要来源。 | Birsen Aydemir Ilhan Onaran Ali R. Kiziler Bulent Alici Mehmet C. Akyolcu | 2007 | Asian Journal of Andrology2007，9，1： | 7 |
| 3 | Effects of coal damage on permeability and gas drainage performance显示文摘Coal permeability is a measure of the ability for fluids to flow through coal structures. It is one of the most important parameters affecting the gas drainage performance in underground coal mines. Despite the extensive research conducted on coal permeability, few studies have considered the effect of coal damage on permeability. This has resulted in unreliable permeability evaluation and prediction. The aim of this study is to investigate the effect of coal damage on permeability and gas drainage performance. The Cui-Bustin permeability model was improved by taking into account the impact of coal damage on permeability. The key damage coefficient of the improved permeability model is determined based on the published permeability data. A finite-element numerical simulation was then developed based on the improved permeability model to investigate the damage areas and the permeability distribution around roadway. Results showed that the tensile failure occurs mainly on the upper and lower sides of the roadway while the shear failure symmetrically occurs on the left and right sides. With the increase in the friction angle value, the damage area becomes small. A good agreement was obtained between the results of the improved permeability model(c = 3) and the published permeability data. This indicated a more accurate permeability prediction by the improved permeability model. It is expected that the findings of this study could provide guidance for in-seam gas drainage borehole design and sealing, in order to enhance the gas drainage performance and reduce gas emissions into underground roadways. | Zheng Chunshan Mehmet Kizil Chen Zhongwei Saiied Aminossadati | 2017 | International Journal of Mining Science and Technology2017，27，5： | 6 |
| 4 | Alzheimer’s disease, neural stem cells and neurogenesis: cellular phase at single-cell level显示文摘Alzheimer’s disease cannot be cured as of yet.Our current understanding on the causes of Alzheimer’s disease is limited.To develop treatments,experimental models that represent a particular cellular phase of the disease and more rigorous scrutiny of the cellular pathological mechanisms are crucial.In recent years,Alzheimer’s disease research underwent a paradigm shift.According to this tendency,Alzheimer’s disease is increasingly being conceived of a disease where not only neurons but also multiple cell types synchronously partake to manifest the pathology.Knowledge on every cell type adds an alternative approach and hope for the efforts towards the treatment.Neural stem cells and their neurogenic ability are making an appearance as a new aspect of the disease manifestation based on the recent findings that neurogenesis reduces dramatically in Alzheimer’s disease patients compared to healthy individuals.Therefore,understanding how neural stem cells can form new neurons in Alzheimer’s disease brains holds an immense potential for clinics.However,this provocative idea requires further evidence and tools for investigation.Recently,single cell sequencing appeared as a revolutionary tool to understand cellular programs in unprecedented resolution and it will undoubtedly facilitate comprehensive investigation of different cell types in Alzheimer’s disease.In this mini-review,we will touch upon recent studies that use single cell sequencing for investigating cellular response in Alzheimer’s disease and some consideration pertaining to the utilization of neural regeneration for Alzheimer’s disease research. | Mehmet Ilyas Cosacak Prabesh Bhattarai Caghan Kizil | 2020 | Neural Regeneration Research2020，15，5： | 4 |
| 5 | Development of a multi-layer perceptron artificial neural network model to determine haul trucks energy consumption显示文摘The mining industry annually consumes trillions of British thermal units of energy,a large part of which is saveable.Diesel fuel is a significant source of energy in surface mining operations and haul trucks are the major users of this energy source.Cross vehicle weight,truck velocity and total resistance have been recognised as the key parameters affecting the fuel consumption.In this paper,an artificial neural network model was developed to predict the fuel consumption of haul trucks in surface mines based on the gross vehicle weight,truck velocity and total resistance.The network was trained and tested using real data collected from a surface mining operation.The results indicate that the artificial neural network modelling can accurately predict haul truck fuel consumption based on the values of the haulage parameters considered in this study. | Soofastaei Ali Aminossadati Saiied M. Arefi Mohammad M. Kizil Mehmet S. | 2016 | International Journal of Mining Science and Technology2016，26，2： | 4 |
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