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439篇 您的检索式：作者名="Meissner M"

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	题名	作者	年代	出处	被引量
1	PI 3-kinase pathway is responsible for antiapoptotic effects of atrial natriuretic peptide in rat liver transplantation显示文摘AIM:To investigate the in vivo effect of atrial natriureticpeptide(ANP)and its signaling pathway during ortho-topic rat liver transplantation.METHODS:Rats were infused with NaCl,ANP(5 μg/kg),wortmannin(WM,16 μg/kg),or a combination ofboth for 20 min.Livers were stored in UW solution(4°C)for 24 h,transplanted and reperfused.Apoptosis wasexamined by caspase-3 activity and TUNEL staining.Phosphorylation of Akt and Bad was visualized by West-ern blotting and phospho-Akt-localization by confocalmicroscopy.RESULTS:ANP-pretreatment decreased caspase-3activity and TUNEL-positive cells after cold ischemia,indicating antiapoptotic effects of ANP in vivo.The an-tiapoptotic signaling of ANP was most likely caused byphosphorylation of Akt and Bad,since pretreatment withPI 3-kinase inhibitor WM abrogated the ANP-inducedreduction of caspase-3 activity.Interestingly,analysis ofliver tissue by confocal microscopy showed translocationof phosphorylated Akt to the plasma membrane of hepa-tocytes evoked by ANP.CONCLUSION:ANP activates the PI-3-kinase pathwayin the liver in vivo leading to phosphorylation of Bad, an event triggering antiapoptotic signaling cascade inischemic liver.	Uwe Grutzner Melanie Keller Michael Bach Alexandra K Kiemer Herbert Meissner Manfred Bilzer Stefan Zahler Alexander L Gerbes Angelika M Vollmar	2006	World Journal of Gastroenterology2006，12，7：	3
2	Varicella prevention in the United States: A review of successes and challenges 显示文摘	MARIN M MEISSNER HC SEWARD JF	2008	Pediatrics2008，122，3：	1
3	Brain injury after gunshot wounding: morphometric analysis of cell destruction caused by temporary cavitation 显示文摘	Oehmichen M Meissner C Konig HG	2000	Neurotrauma2000，17，2：	1
4	In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state显示文摘	Wernig M Meissner A Foreman R	2007	Nature2007，448，7151：	1
5	Effects of sheep exclusion on the soil seed bank and annual vegetation in chenopod shrub lands of South Australia显示文摘	Meissner R A Facelli J M	1999	Journal of Arid Environment1999，42，2：	1
6	Brain injury after gunshot wounding:morphometric analysis of cell destruction caused by temporary cavitation显示文摘	Oehmichen M Meissner C Konig HG		0，，02：	1
7	Effect of sheep exclusion on the soil seed bank and annual vegetation in chenopod shrub lands of South Australia 显示文摘	Meissner R A Facelli J M	1999	Journal of Arid Environment1999，42，2：	1
8	Analytical stress characteri- zation after different chip separation Methods显示文摘	Fuegl M Mackh G Meissner E	2014	Microelectronics Reliability(S0026-2714)2014，54，910：	1
9	Childhood vaccination against chickenpox: an analysis of benefits and costs 显示文摘	Huse D M Meissner H C Lacey M J	1994	J Pediatr1994，124，6：	1
10	Role of Toxoplasma gondii myosin A in powering parasite gliding and host cell invasion 显示文摘	Meissner M Schluter D Soldati D	2002	Science2002，29，8：	1
11	Priorities in Parkinson's disease research显示文摘	Meissner WG Frasier M Gasse T		0，，：	1
12	Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells显示文摘	Meissner A M Wernig	2007	Nat Biotech2007，25，10：	1
13	Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells显示文摘	Meissner A Wernig M Jaeniscb R	2007	Nat Biotechnol2007，25，10：	1
14	Pontine axonal injury after brain trauma and nontraumatic hypoxic-ischemic brain damage显示文摘	Oehmichen M Meissner C Schmidt V	1999	Int J Legal Med1999，112，4：	1
15	e-Myc is dispensable for direct reprogramming of mouse fibroblasts 显示文摘	Wernig M Meissner A Cassady JP	2008	Cell Stem Cell2008，2，：	1
16	Human papillomavirus prevalence in women with normal cytology and with cervical cancer in Natal显示文摘	Fernandes J V Meissner R de V Carvalho M G	2011	Brazil Mol Med Rep2011，4，6：	1
17	Self-sustained deep cavity oscillation induced by grazing flow显示文摘	Meissner M	1987	Aeustica1987，62，：	1
18	Priorities in Parkinson's disease research显示文摘	Meissner WG Frasier M Gasser T	2011	Nat Rev Drug Discov2011，10，5：	1
19	The spectrum of blunt injury to the carotid artery:a multicenter perspective显示文摘	Cogbill TH Moore EE Meissner M	1994	J Trauma1994，37，：	1
20	The hemodynamics and diagnosis of venous disease显示文摘	Meissner M H Moneta G Burnand K	2007	J Vasc Surg2007，46，：	1

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