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14篇 您的检索式:作者名="Melnikov A L"
    题名 作者 年代 出处 被引量
1Diffraction by extremely small holes inthin absorbing and transparent screens and by disks显示文摘TSOY V I MELNIKOV L A 2008Optics Com-munications2008,281,8:1
2Regular integral sum graphs 显示文摘MELNIKOV L PYATKIN A 2002Discrete Mathematics2002,252,:1
3Regular integral sum graphs 显示文摘 Pyatkin A V 2002Discrete Math2002,252,:1
4Fe-Mn and mineralization on the IOAN Guyot,Western Pacific: results of a detailed survey显示文摘Melnikov M L Shkolnik E L Pulyaeva I A 1996Geol of Pac Ocean1996,12,:1
5显示文摘Melnikov A Sigov A Vorotiov K Davydov A Topalova L 1999J Crystal Growth1999,197,:1
6Disease modifying treatment of spinal cord injury with directly reprogrammed neural precursor cells in non-human primates显示文摘BACKGROUND The development of regenerative therapy for human spinal cord injury(SCI)is dramatically restricted by two main challenges:the need for a safe source of functionally active and reproducible neural stem cells and the need of adequate animal models for preclinical testing.Direct reprogramming of somatic cells into neuronal and glial precursors might be a promising solution to the first challenge.The use of non-human primates for preclinical studies exploring new treatment paradigms in SCI results in data with more translational relevance to human SCI.AIM To investigate the safety and efficacy of intraspinal transplantation of directly reprogrammed neural precursor cells(drNPCs).METHODS Seven non-human primates with verified complete thoracic SCI were divided into two groups:drNPC group(n=4)was subjected to intraspinal transplantation of 5 million drNPCs rostral and caudal to the lesion site 2 wk post injury,and lesion control(n=3)was injected identically with the equivalent volume of vehicle.RESULTS Follow-up for 12 wk revealed that animals in the drNPC group demonstrated a significant recovery of the paralyzed hindlimb as well as recovery of somatosensory evoked potential and motor evoked potential of injured pathways.Magnetic resonance diffusion tensor imaging data confirmed the intraspinal transplantation of drNPCs did not adversely affect the morphology of the central nervous system or cerebrospinal fluid circulation.Subsequent immunohistochemical analysis showed that drNPCs maintained SOX2 expression characteristic of multipotency in the transplanted spinal cord for at least 12 wk,migrating to areas of axon growth cones.CONCLUSION Our data demonstrated that drNPC transplantation was safe and contributed to improvement of spinal cord function after acute SCI,based on neurological status assessment and neurophysiological recovery within 12 wk after transplantation.The functional improvement described was not associated with neuronal differentiation of the allogeneic drNPCs.Instead,directed drNPCs migration to the areas of active growth cone formation may provide exosome and paracrine trophic support,thereby further supporting the regeneration processes.Vladimir P Baklaushev Oleg V Durov Vladimir A Kalsin Eugene V Gulaev Sergey V Kim Ilya L Gubskiy Veronika A Revkova Ekaterina M Samoilova Pavel A Melnikov Dzhina D Karal-Ogly Sergey V Orlov Alexander V Troitskiy Vladimir P Chekhonin Alexander V Averyanov Jan-Eric Ahlfors 2021World Journal of Stem Cells2021,13,5:1
7Regular integral sum graphs 显示文摘MELNIKOV L S PYATKIN A V 2002Discrete Mathematics2002,252,3:1
8Wiener index, line graphs and the cyclomatic number显示文摘DOBRYNIN A A MELNIKOV L S 2005Match Commun Math Comput Chem2005,53,:1
9Joint optimal object shape estimation and encoding 显示文摘Kondi L P Melnikov G and Katsaggelos A K 2004IEEE Transactions on Circuits and Systems for Video Technology2004,14,4:1
10Regular integral sum graphs显示文摘 Pyatkin A V 2002Discrete Math2002,252,:1
11Thoracic paraverte- bral block versus transversus abdominis plane block in major gynecological surgery: a prospective, randomized, controlled, observer-blinded study显示文摘Melnikov A L Bjoergo S Kongsgaard U E 2012Local Reg Anesth2012,5,:1
12Regular Integral Sum Graphs 显示文摘Melnikov L S Pyatkin A V 2002Discrete Math2002,252,:1
13Tree quadratic line graph and the iener index显示文摘DOBRYNIN A A MELNIKOV L S 2004Croat Chem Acta2004,77,3:1
14Analysis of non-ionized substance losses in experiments on plasma mass separation显示文摘Plasma mass separation requires a lot of diagnostic techniques that not only demonstrate the separation effect but also show the efficiency of the process.During the test experiments,plasma flux to be separated may contain neutral particles that avoid the separation process due to their insensitivity to electromagnetic field.We present the diagnostics of the lost substance in experiments on plasma mass separation.The obtained data of the diagnostics helps determine the law of particle evaporation from the plasma source.We show that neutral flux is unable to distort the result of separation diagnostics.The presented approach can be used in experiments aimed at enhancing the separation effect and achieving target productivity for industry applications.R A USMANOV N N ANTONOV A V GAVRIKOV G D LIZIAKIN A D MELNIKOV A P OILER V P SMIRNOV R A TIMIRKHANOV L S VOLKOV N A VORONA 2022Plasma Science and Technology2022,24,8:0
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