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| 1 | Resected specimen evaluation,anorectal manometry,endoanal ultrasonography and clinical follow-up after STARR procedures显示文摘AIM:To investigate stapled transanal rectal resection (STARR) procedures as surgical techniques for obstructed defecation syndrome (ODS) by analyzing specimen evaluation,anorectal manometry,endoanal ultrasonography and clinical follow-up.METHODS:From January to December 2007,we have treated 30 patients.Fifteen treated with double PPH-01 staplers and 15 treated using new CCS 30 contour.Resected specimen were measured with respect to average surface and volume.All patients have been evaluated at 24 mo with clinical examination,anorectal manometry and endoanal ultrasonography.RESULTS:Average surface in the CCS 30 group was 54.5 cm2 statistically different when compared to the STARR group (36.92 cm2).The average volume in the CCS 30 group was 29.8 cc,while in the PPH-01 it was23.8 cc and difference was statistically significant.The mean hospital stay in the CCS 30 group was 3.1 d,while in the PPH-01 group the median hospital stay was 3.4 d.As regards the long-term follow-up,an overall satisfactory rate of 83.3% (25/30) was achieved.Endoanal ultrasonography performed 1 year following surgery was considered normal in both of the studied groups.Mean resting pressure was higher than the preoperative value (67.2 mmHg in the STARR group and 65.7 mmHg in the CCS30 group vs 54.7 mmHg and 55.3 mmHg,respectively).Resting and squeezing pressures were lower in those patients not satisfied,but data are not statistically significant.CONCLUSION:The STARR procedure with two PPH-01 is a safe surgical procedure to correct ODS.The new Contour CCS 30 could help to increase the amount of the resected tissue without differences in early complications,post-operative pain and in hospital stay compared to the STARR with two PPH-01 technique. | Gabriele Naldini Guido Cerullo Claudia Menconi Jacopo Martellucci Simone Orlandi Nicola Romano Mauro Rossi | 2011 | World Journal of Gastroenterology2011，17，19： | 6 |
| 2 | Isolation, screening and identifi cation of Bacillus spp. as direct-fed microbial candidates for aflatoxin B_1 biodegradation显示文摘Objective: To evaluate the ability of Bacillus spp. as direct-fed microbials(DFM) to biodegrade al atoxin B1(AFB1) by using an in vitro digestive model simulating in vivo conditions.Methods: Sixty-nine Bacillus isolates were obtained from intestines, and soil samples were screened by using a selective media method against 0.25 and 1.00 μg/m L of AFB1 in modii ed Czapek-Dox medium. Plates were incubated at 37 °C and observed every two days for two weeks. Physiological properties of the three Bacillus spp. candidates were characterized biochemically and by 16 S r RNA sequence analyzes for identii cation. Tolerance to acidic p H, osmotic concentrations of Na Cl, bile salts were tested, and antimicrobial sensitivity proi les were also determined. Bacillus candidates were individually sporulated by using a solid fermentation method and combined. Spores were incorporated into 1 of 3 experimental feed groups: 1) Negative control group, with unmedicated starter broiler feed without AFB1; 2) Positive control group, with negative control feed contaminated with 0.01% AFB1; 3) DFM treated group, with positive control feed supplemented with 109 spores/g. After digestion time(3:15 h), supernatants and digesta were collected for high-performance liquid chromatography l uorescence detection analysis by triplicate.Results: Three out of those sixty-nine DFM candidates showed ability to biodegrade AFB1 in vitro based on growth as well as reduction of l uorescence and area of clearance around each colony in modii ed Czapek-Dox medium which was clearly visible under day light after 48 h of evaluation. Analysis of 16S-DNA identii ed the strains as Bacillus amyloliquefaciens, Bacillus megaterium and Bacillus subtilis. The three Bacillus strains were tolerant to acidic conditions(p H 2.0), tolerant to a high osmotic pressure(Na Cl at 6.5%), and were able to tolerate 0.037% bile salts after 24 h of incubation. No signii cant dif erences(P > 0.05) were observed in the concentrations of AFB1 in neither the supernatants nor digesta samples evaluated by highperformance liquid chromatography with l uorescence detection between positive control or DFM treated groups. Conclusions: In vitro digestion time was not enough to confirm biodegradation of AFB1. Further studies to evaluate the possible biodegradation ef ects of the BacillusDFM when continuously administered in experimentally contaminated feed with AFB1, are in progress. | Rosario Galarza-Seeber Juan David Latorre Xochitl Hernandez-Velasco Amanda Drake Wolfenden Lisa Renee Bielke Anita Menconi Billy Marshall Hargis Guillermo Tellez | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，9： | 3 |
| 3 | Tailored prolapse surgery for the treatment of haemorrhoids and obstructed defecation syndrome with a new dedicated device: TST STARR Plus显示文摘 | Gabriele Naldini Jacopo Martellucci Roberto Rea Stefano Lucchini Michele Schiano di Visconte Angelo Caviglia Claudia Menconi Donglin Ren Ping He Domenico Mascagni | 2014 | International Journal of Colorectal Disease2014，，5： | 2 |
| 4 | Computational information for the logistic map at the chaos threshold显示文摘 | Bonanno C Menconi G | 2002 | Discrete and Continuous Dynamical Systems-Series B2002，3，2： | 1 |
| 5 | Environmental trig- gers of thyroiditis : hepatitis C and interferon -a显示文摘 | MENCONI F HASHAM A TOMER Y | 2011 | J Endo- crinol Invest2011，34，1： | 1 |
| 6 | Nitric oxide donor-induced hyperpermeability of cultured intestinal epithelial monolayers:role of superoxide radical,hydorxyl radical,and peroxynitrite显示文摘 | Unno N Smith M | 1998 | Biochem Biophys Acta1998，1425，1： | 1 |
| 7 | Acidosis induces hyper-permeability in CaCo 2BBe Cultured intestinal epithelial monolayers 显示文摘 | Menconi M J Salzman A 1 Unno N | 1997 | Am J Physiol1997，273，： | 1 |
| 8 | Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis : from epidemiology to mechanisms显示文摘 | Huber A Menconi F Corathers S Jacobson EM Tomer Y | 2008 | Endocr Rev2008，29，6： | 1 |
| 9 | Treatment of culturedmyotubes with the calcium ionophore A23187 increases protea- some activity via a CaMK Ⅱ-caspase-calpain-dependent mecha- nism显示文摘 | Menconi M J Wei W Yang H | 2004 | Surgery2004，136，2： | 1 |
| 10 | Treatment of cultured myotubes with the calcium ionophore A23187 increases proteasome activity via a CaMK II-caspase-calpain-dependent mechanism显示文摘 | Menconi MJ Wei W Yang H | | 0，，： | 1 |
| 11 | Hyperpermeability of monolayers is induced by NO : Effect of low extracellular pH显示文摘 | Unno N Menconi M J Smith M | 1997 | Am J Physiol1997，272，51： | 1 |
| 12 | Model integrated of life-cycle costing and dynamic thermal simulation (MILD) to evaluate roof insulation materials for existing livestock buildings 显示文摘 | Menconi M E Grohmann D | 2014 | Energy and Buildings2014，81，： | 1 |
| 13 | The management of malignant pericardial effusions using permanently implanted devices显示文摘 | Melfi FM Menconi GF Chella A | 2002 | Eur J Cardiothorac Surg2002，21，2： | 1 |
| 14 | Dynamic thermal simulation on retrofitting scenarios for semi-extensive sheep farms显示文摘 | Menconi M E Grohmann D Borghi P | 2014 | J Agric Eng2014，45，2： | 1 |
| 15 | Tailored prolapse surgery for the treatment of hemorrhoids with a new dedicated device: TST Starr plus显示文摘 | Naldini G Fabiani B Menconi C | 2015 | Int J Colorectal Dis2015，30，12： | 1 |
| 16 | Nitric oxide dilates tight junction and depletes ATP in cultured Caco-2BBe intestinal epithelial monolyers显示文摘 | Salzman AL Menconi M J Unno N | 1995 | Am J Physiol1995，268，2： | 1 |
| 17 | Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes 显示文摘 | Menconi M Gonnella P Petkova V | 2008 | J Cell Biochem2008，105，2： | 1 |
| 18 | Type 1 diabetes and autoimmune thyroiditis:The genetic connection 显示文摘 | Tomer Y Menconi F | 2009 | Thyroid2009，19，2： | 1 |
| 19 | Diagnosis and classification of Graves' disease显示文摘 | Menconi F Marcocci C Marinò M | 2014 | Utoimmun Rev2014，13，4： | 1 |
| 20 | P-glyoopmtein-170 inhibition significantly reduces cortisol and ciclosperin effhix from human intestinal epithelial cell and T lymphocytes显示文摘 | Farrell RJ Menconi MJ Keates AC | 2002 | Aliment Pharmacel Ther2002，16，5： | 1 |
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