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| 1 | Assessing the relationship between the rumen microbiota and feed efficiency in Nellore steers显示文摘Background:Ruminants rely upon a complex community of microbes in their rumen to convert host-indigestible feed into nutrients.However,little is known about the association between the rumen microbiota and feed efficiency traits in Nellore(Bos indicus)cattle,a breed of major economic importance to the global beef market.Here,we compare the composition of the bacterial,archaeal and fungal communities in the rumen of Nellore steers with high and low feed efficiency(FE)phenotypes,as measured by residual feed intake(RFI).Results:The Firmicutes to Bacteroidetes ratio was significantly higher(P<0.05)in positive-RFI steers(p-RFI,low feed efficiency)than in negative-RFI(n-RFI,high feed efficiency)steers.The differences in bacterial composition from steers with high and low FE were mainly associated with members of the families Lachnospiraceae,Ruminococcaceae and Christensenellaceae,as well as the genus Prevotella.Archaeal community richness was lower(P<0.05)in p-RFI than in n-RFI steers and the genus Methanobrevibacter was either increased or exclusive of p-RFI steers.The fungal genus Buwchfawromyces was more abundant in the rumen solid fraction of n-RFI steers(P<0.05)and a highly abundant OTU belonging to the genus Piromyces was also increased in the rumen microbiota of highefficiency steers.However,analysis of rumen fermentation variables and functional predictions indicated similar metabolic outputs for the microbiota of distinct FE groups.Conclusions:Our results demonstrate that differences in the ruminal microbiota of high and low FE Nellore steers comprise specific taxa from the bacterial,archaeal and fungal communities.Biomarker OTUs belonging to the genus Piromyces were identified in animals showing high feed efficiency,whereas among archaea,Methanobrevibacter was associated with steers classified as p-RFI.The identification of specific RFI-associated microorganisms in Nellore steers could guide further studies targeting the isolation and functional characterization of rumen microbes potentially important for the energy-harvesting efficiency of ruminants. | Déborah Romaskevis Gomes Lopes Márcio de Souza Duarte Alex J.La Reau Ibrahim Zuniga Chaves Tiago Antônio de Oliveira Mendes Edenio Detmann Cláudia Braga Pereira Bento Maria Eugênia Zerlotti Mercadante Sarah Figueiredo Martins Bonilha Garret Suen Hilário Cuquetto Mantovani | 2021 | Journal of Animal Science and Biotechnology2021，12，4： | 3 |
| 2 | 载脂蛋白E基因型影响老年人心输出量与认知功能的相关性显示文摘心输出量的轻微下降与低脑血流量相关,尤其是在阿尔茨海默病病理改变的首发区域。载脂蛋白E(apolipoprotein E,APOE)-ε4是阿尔茨海默病的一个遗传易感性危险因素,同时能减轻血管损伤。该研究旨在探讨携带APOE-ε4基因是否影响心输出量与认知功能的相关性。研究人员纳入范德比尔特记忆老化项目中无临床脑卒中和痴呆的参与者306例,平均年龄(73±7)岁,其中42%为女性。 | 陈嘉睿 刘莉 Bown CW Liu D Osborn KE Gupta DK Mendes LA Pechman KR Hohman TJ Wang TJ Gifford KA Jefferson AL | 2019 | 中华高血压杂志2019，27，10： | 2 |
| 3 | Phenylalanine hydroxylase deficiency:Molecular epidemiology and predictable BH (4)-responsiveness in South Portugal PKU patients显示文摘 | Rivera I Mendes D Afonso A | 2011 | Mol Genet Metab2011，104，1： | 1 |
| 4 | Resurfacing of goat articular cartilage by chondrocytes derived from bone marrow 显示文摘 | Butnariu-Ephrat M Robinson D Mendes DG | 1996 | Clin Orthop1996，330，： | 1 |
| 5 | Resurfacing of gaot articular cartilage by chondrocytes derived from bone marrow显示文摘 | Butnariu-E phratM Robinson D Mendes DG | 1996 | Clin O rthop1996，，330： | 1 |
| 6 | MRI finding in Rasmussen's en- cephalitis显示文摘 | Mendes D Moreno T Sd G et aI | 2012 | Acta Med Port2012，25，1： | 1 |
| 7 | Plantar pressures and ground reaction forces during walking of individuals with uni- lateral transfemoral amputation 显示文摘 | Castro ME Soares D Mendes E | 2014 | PM R2014，6，8： | 1 |
| 8 | Manufacturing Firm Reaction to Supplier Failure and Recovery显示文摘 | Marcos Andre Mendes P Kevin D Rungtusanatham M J | 2007 | International Journal of Operations & Production Management2007，27，3： | 1 |
| 9 | Resurfacing of gaot articular cartilage by chondrocytes derived from bone marrow显示文摘 | BUTNARIU E M ROBINSON D MENDES D G | 1996 | Clin Orthop1996，，330： | 1 |
| 10 | Optimal scheduling of spinning reserve 显示文摘 | Gooi H B Mendes D P Be11 K R W | 1999 | IEEE Transactions on Power Systems1999，14，4： | 1 |
| 11 | Aging study of carbon molecular sieve membranes显示文摘 | Lagorsse S Magalhdes F D Mendes A | 2008 | J Membr Sei2008，310，12： | 1 |
| 12 | The origin of cor- relations in metabolomics data显示文摘 | Camacho D De La Fuente A Mendes P | 2005 | Metabolomics2005，1，1： | 1 |
| 13 | 牙周炎与高血压的相关性显示文摘牙周炎是一种常见的慢性炎症性疾病,可能会对血压产生重要影响。本研究旨在探究:(1)在一项大型代表性队列中研究牙周健康与血压的相关性;(2)牙周炎在未明确诊断血压升高患者中的诊断预测价值;(3)年龄是否在牙周健康与血压的相关性中起介导作用。在纳入随机招募的参与者1057例[平均年龄(60.9±16.3)岁,57.7%为女性]中行牙周临床评估,并使用自动血压计测量单次血压。 | 袁源(摘译) 练桂丽(审校) Machado V Aguilera EM Botelho J Hussain SB Leira Y Proenca L D’Aiuto F Mendes JJ | 2020 | 中华高血压杂志2020，28，9： | 1 |
| 14 | Diabetes mellitus and intracranial stenosis显示文摘 | BAPTISTA D SOARES F | 1999 | Rev Neurol1999，28，11： | 1 |
| 15 | Analysis of torsional vibration in internal combustion engines:modeling and experimental validation显示文摘 | MENDES A MEIRELLES P S ZAMPIERI D E | 2008 | Proceedings of the Institution of Mechanical Engineers Part K:Journal of Multi-body Dynamics2008，222，： | 1 |
| 16 | Approach to prophylactic measures for central venous catheter-related infections in hemodialysis:A critical review显示文摘 | Silva TN de Marchi D Mendes ML | 2014 | Hemodial Int2014，18，1： | 1 |
| 17 | Recovery of nickel and cobalt from acid leach pulp by ion exchange using chelating resin显示文摘 | Mendes F D Martins A H | 2005 | Minerals Engineering2005，2，： | 1 |
| 18 | Expression of transforming growth factor-beta1 and hypoxia-inducible factor-1alpha in an experimental model of kidney transplantation显示文摘 | Lario S Mendes D Bescòs M | 2003 | Transplantation2003，75，10： | 1 |
| 19 | Homocysteine thiolactone induces cardiac dysfunction :role of oxidative stress显示文摘 | Mendes RH Sirvente RA Candido GO Mostarda C Salemi VM D' Almeida V | 2010 | J Cardiovasc Pharma- col2010，55，2： | 1 |
| 20 | LEADER Program results for 2009:an activity and spectrum analysis of linezolid using 6 414 clinical isolates from 56 medical centers in the United States显示文摘 | Farrell D J Mendes RE Ross JE | 2011 | Antimicrob Agents Chemother2011，55，8： | 1 |
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