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| 1 | Idarubicin intensified BUCY2 regimen in allogeneic unmanipulated transplant for high-risk hematological malignancies 显示文摘 | Mengarelli A Iori AP Guglielmi C | 2000 | Leukemia2000，14，12： | 1 |
| 2 | Fibromodulin distribution and association with collagen 显示文摘 | Hedlund H Mengarelli -Widholm S Heineglird D | 1994 | Matrix Biol1994，14，3： | 1 |
| 3 | Use of multicolor flow cytometry for isolation of specific cell populations deriving from differentiated human embryonic stem cells显示文摘 | Mengarelli I Fryga A Barberi T | | 0，，04： | 1 |
| 4 | Assessment of the ankle muscle co-contraction during normal gait: A surface electromyography study显示文摘 | Di Nardo F Mengarelli A Maranesi E | 2015 | J Electromyogr Kinesiol2015，25，2： | 1 |
| 5 | Myelodysplastic syndromes in patients under 50 years old; a single institution experience 显示文摘 | Breccia M Mengarelli A Mancini M | 2005 | Leuk Res2005，29，7： | 1 |
| 6 | Standard versus alternative myeloablative conditioning regimens in allogeneic hematopoietie stem cell transplantation for high-risk acute leukemia显示文摘 | Mengarelli A lori A Guglielmi C | 2002 | Haematologica2002，87，1： | 1 |
| 7 | Idarubicin intensified BUCY2 regimen in allogeneic unmanipulated transplant for high-risk hematological malignancies 显示文摘 | MENGARELLI A IORI AP GUGLIELMI C | 2000 | Leukemia2000，14，12： | 1 |
| 8 | Standard versus alterna tive myeloablative conditioning regimens in allogeneic hematopoiet ic stem cell transplantation for high-risk acute leukemia显示文摘 | Mengarelli A Iori A P Guglielmi C | 2002 | Haenatologica2002，87，： | 1 |
| 9 | Derivation of multiple cranial tissues and isolation of lens epithelium-like cells from human embryonic stem cells 显示文摘 | Mengarelli I Barberi T | 2013 | Stem Cells Transl Med2013，2，2： | 1 |
| 10 | Myelodysplastic syndromes in patients under 50 years old:A single institution experience显示文摘 | Breccia M Mengarelli A Mancini M | 2005 | Leuk Res2005，29，7： | 1 |
| 11 | Granuloytic sarcoma of the pancreas successfully treated with intensive chemotherapy and stem cell transplantation 显示文摘 | Breccia M Andream D Mengarelli A | 2003 | Eur J Haematol2003，70，： | 1 |
| 12 | Derivation of multiple cranial tissues and isola- tion of lens epithelium-like cells from human embryonic stem cells 显示文摘 | Mengarelli I Barberi T | 2013 | Stem Cells Trartsl Med2013，2，2： | 1 |
| 13 | Standard versus alternative myeloablative conditioning regimens in allogeneic hematopoietic stem cell transplantation for high-risk acute leukemia 显示文摘 | Mengarelli A Iori AP Guglielmi C | 2002 | Haematologica2002，87，2： | 1 |
| 14 | Standard versus alternative myeloablative conditioning regimens in aUogeneic hematopoietic stem cell transplantation for high-risk acute leukemia显示文摘 | Mengarelli A Iori A Gnglielmi C | 2002 | Haematolngica2002，87，1： | 1 |
| 15 | Myelodysplastic syndromes in patients under 50 years old: a single institution experience显示文摘 | BRECCIA M MENGARELLI A MANCINI M | 2005 | Leuk Res2005，29，： | 1 |
| 16 | Myelodysplastic syndromes in patients under 50 years old :a single institution experience显示文摘 | Breccia M Mengarelli A Mancini M | 2005 | Leuk Res2005，29，7： | 1 |
| 17 | Granulocytic sarcoma of the pancreas successfully treated with intensive chemotherapy and stem cell transplantation 显示文摘 | BaumBreccia M d'Andrea M Mengarelli A | 2003 | European Journal of Haematology2003，70，3： | 1 |
| 18 | Effect of hormone replacement therapy upon haemorheological variables显示文摘 | Spengler MI Goni GM Mengarelli G | 2003 | Clin Hemorheol Microcirculation2003，28，1： | 1 |
| 19 | Cytomegalovirus reactivation after autologous stem cell transplantation in myeloma and lymphoma patients:A single-center study显示文摘AIM: To determine the incidence of and the risk factors for cytomegalovirus(CMV) symptomatic infection and end-organ disease after autologous stem cell transplantation(ASCT).METHODS: A total of 327 consecutive non CD34+ selected autografts performed from the Hematology and Stem Cell Transplantation Unit of Regina Elena National Cancer Institute of Rome(Italy) in the period comprised between January 2003 to January 2015, were reviewed. Over the 327 autografts, 201 were performed in patients with multiple myeloma, whereas the remaining 126 in patients affected by non-Hodgkin's lymphoma and Hodgkin's lymphoma. The patients who underwent an ASCT for an acute leukemia(n = 20) in the sameperiod were excluded from this analysis. CMV DNA load in the blood has been determined by polymerasechain reaction in the case of a clinical suspicion of reactivation, therefore, no routine monitoring strategy was adopted. In the presence of signs and symptoms of CMV reactivation an antiviral treatment was performed.RESULTS: Overall, 36 patients(11%) required a specific antiviral treatment for a symptomatic CMV reactivation(n = 32) or an end-organ disease(n = 4). We observed 20 and 16 cases of CMV reactivation among lymphoma(16%) and myeloma patients(8%), respectively. Among cases of end-organ disease, 3 were diagnosed as interstitial pneumonia and one remaining case as hemorrhagic enteritis. All cases of CMV reactivation were observed in Ig G seropositive patients, with no documented cases of primary CMV infection. All patients were treated with a specific antiviral therapy, with a global rate of hospitalization of 55%; four patients received intravenous immunoglobulins. Transplantrelated mortality was significantly higher in patients who experienced a CMV reactivation(8.4% ± 4.7% vs 1.7% ± 0.8%; P = 0.047). In univariate analysis, a pretransplant HBc Ig G seropositivity, a diagnosis of T-cell non-Hodgkin's lymphoma and higher median age at transplant were significantly associated with the risk of developing a clinically relevant CMV infection requiring specific antiviral therapy(P < 0.001, P = 0.042 and P = 0.004, respectively). In multivariate analysis, only a pretransplant HBc Ig G seropositivity(OR = 8.928, 95%CI: 1.991-33.321; P = 0.023) and a diagnosis of T-cell nonHodgkin's lymphoma(OR = 4.739, 95%CI: 1.511-11.112; P = 0.042) proved to be independent predictors of a post-transplant clinically relevant CMV reactivation. CONCLUSION: A symptomatic CMV infection can occur in about 11% of adult patients with lymphoma or myeloma undergoing ASCT. A pre-transplant HBc Ig G seropositivity and a diagnosis of T-cell non-Hodgkin's lymphoma should be considered as independent predictor factors of CMV reactivation. | Francesco Marchesi Fulvia Pimpinelli Svitlana Gumenyuk Daniela Renzi Francesca Palombi Francesco Pisani Atelda Romano Antonio Spadea Elena Papa Marco Canfora Fabrizio Ensoli Andrea Mengarelli | 2015 | World Journal of Transplantation2015，5，3： | 0 |
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