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1篇 您的检索式:作者名="Menghuan Guo"
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1Role of miR-302/367 cluster in human physiology and pathophysiology显示文摘MicroRNAs(miRNAs)are small non-coding RNAs that negatively regulate target mRNAs at the post-transcriptional level.Increasing evidence shows the involvement of miRNAs in diverse biological processes.miR-302/367 cluster is highly conserved among vertebrates and made up of five members,including miR-367,miR-302a,miR-302b,miR-302c and miR-302d.miR-302/367 cluster plays an important role in cell proliferation,differentiation and reprogramming,affecting the development of tumor,cardiovascular system,nervous system and immune system.In this review,we will summarize the role of miR-302/367 cluster in embryonic stem cells and induced pluripotent stem cells and try to point out its relationship with tumors,cardiovascular system,nervous system and immune system.Menghuan Guo Lu Gan Jing Si Jinhua Zhang Zhiyuan Liu Jin Zhao Zhong Gou Hong Zhang 2020Acta Biochimica et Biophysica Sinica2020,52,8:0
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