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		题名	作者	年代	出处	被引量
	1	Pit-and trench-forming osteoclasts:a distinction that matters显示文摘Osteoclasts(OCs)seeded on bone slices either drill round pits or dig long trenches.Whereas pits correspond to intermittent resorption,trenches correspond to continuous and faster resorption and require a distinct assembly of the resorption apparatus.It is unknown whether the distinction between pits and trenches has any biological relevance.Using OCs prepared from different blood donors,we found that female OCs achieved increased resorption mainly through pit formation,whereas male OCs did so through trench formation.Trench formation went along with high collagenolytic activity and high cathepsin K(CatK)expression,thereby allowing deeper demineralization.A specific CatK inhibitor abrogated the generation of trenches,while still allowing the generation of pits.OCs obtained from bone marrow were more prone to generate trenches than those obtained from blood.Scanning electron microscopy of bone surfaces eroded in vivo showed trenches and pits of similar size as those made by OCs in culture.We conclude that the distinction between trench-and pit-forming OCs is relevant to the differences among OCs from different skeletal sites,different individuals,including gender,and results from differences in colIagenolytic power.This indicates a biological relevance and highlights the importance of discriminating between pits and trenches when assessing resorption.	Ditte MH Merrild Dinisha C Pirapaharan Christina M Andreasen Per Kjxrsgaard-Andersen Anas MJ Mùller Ming Ding Jean-Marie Delaissé Kent Sùe	2015	Bone Research2015，3，4：	2
	2	Recycling of Glass: Account- ing of Greenhouse Gases and Global Warming Contributions显示文摘	Larsen A W Merrild H Christensen T H	2009	Waste Manage Res2009，27，8：	1
	3	Recycling of Wood for Particle Board Production: Accounting of Greenhouse Gases and Global Wanning Contributions 显示文摘	Merrild H Christensen T H	2009	Waste Manage Res2009，27，8：	1
	4	Recycling of Paper: Account ing of Greenhouse Gases and Global Warming Contributions显示文摘	Merrild H Damgaard A Christensen T H	2009	Waste Manage Res2009，27，8：	1
	5	Glucocorticoid-Induced Changes in the Geometry of Osteoclast Resorption Cavities Affect Trabecular Bone Stiffness显示文摘	Jef Vanderoost Kent S?e Ditte Marie Horslev Merrild Jean-Marie Delaissé G. Harry Lenthe	2013	Calcified Tissue International2013，，3：	1
	6	Glucocorticoid-induced changes in the geometry of osteoclast resorption cavities affect trabecular bone stiffness显示文摘	Vanderoost J Soe K Merrild DM	2013	Calcif Tissue Int2013，92，3：	1

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