| 13 | Exploiting synthetic regulatory elements for non-dominant microorganisms显示文摘Engineered genetic devices and gene circuits can reprogram cellular behaviors towards different applications in synthetic biology domains,such as detection of small molecular metabolites,biosynthesis of chemicals or proteins valuable for agriculture,food,chemical and pharmaceutical fields.One of the main barriers for these approaches is the lack of genetic regulatory elements with ideal characteristics in different organisms.Developments of these synthetic elements has been rapidly boosted in the last few years,fueled mostly by generating of artificial promoters,libraries of ribosome binding site(RBS)or 5’untranslated regions(UTRs),genetic switches,protein degrons,etc.Because of the flexibility of usage and great number of regulatory components accessible,many synthetic biology studies and applications have been conducted in microorganisms utilizing the model Escherichia coli or Saccharomyces cerevisiae. | Xuyuan Wang Mersa Darbandsari Lixin Zhang Zixin Deng | 2022 | Synthetic and Systems Biotechnology2022，7，2： | 0 |
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