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75篇 您的检索式:作者名="Metro"
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1Dissection of genetic overlap of salt tolerance QTLs at the seedling and tillering stages using backcross introgression lines in rice显示文摘QTLs for salt-tolerance(ST)related traits at the seedling and tillering stages were identified using 99 BC2F8 introgression lines(IL)derived from a cross between IR64(indica)as a recurrent parent and Binam(japonica)from Iran as the donor parent.Thirteen QTLs affecting survival days of seedlings(SDS), score of salt toxicity of leaves(SST),shoot K + concentration(SKC)and shoot Na + concentration(SNC) at the seedling stage and 22 QTLs underlying fresh weight of shoots(FW),tiller number per plant(TN) and plant height(PH)at the tillering stage were identified.Most QTLs detected at the tillering stage showed obvious differential expression to salt stress and were classified into three types based on their differential behaviors.Type I included 11 QTLs which were expressed only under the non-stress condition.Type II included five QTLs expressed in the control and the salt stress conditions,and three of them(QPh5,QPh8 and QTn9)had similar quantity and the same direction of gene effect,suggesting their expression was less influenced by salt stress.Type III included six QTLs which were detectable only under salt stress,suggesting that these QTLs were apparently induced by the stress.Thirteen QTLs affecting trait difference or trait stability of ILs between the stress and non-stress conditions were identified and the Binam alleles at all loci except QPh4,QTn2 and QFw2a decreased trait difference.The three QTLs less influenced by the stress and 13 QTLs affecting trait stability were considered as ST QTLs which contributed to ST.Comparing the distribution of QTLs detected at the seedling and tillering stages,most(69%)of them were genetically independent.Only four were the same or adjacent regions on chromosomes 1,2,8 and 11 harboring ST QTLs detected at the two stages,suggesting that partial genetic overlap of ST across the two stages occurs.It is likely,therefore,to develop ST rice variety for both stages by pyramiding of ST QTLs of different stages or selection against the overlapping QTLs between the two stages via marker-assisted selection(MAS).ZANG JinPing 1 ,SUN Yong 1 ,WANG Yun 1 ,YANG Jing 1 ,LI Fang 1 ,ZHOU YongLi 1 ,ZHU LingHua 1 , Reys JESSICA2,Fotokian MOHAMMADHOSEIN 2,XU JianLong 1&LI ZhiKang 1,2 1Institute of Crop Sciences/National Key Facility for Crop Gene Resources&Genetic Improvement,Chinese Academy of Agricul- tural Sciences,Beijing 100081,China 2International Rice Research Institute,DAPO Box 7777,Metro Manila,Philippines 2008Science China(Life Sciences)2008,51,7:32
2Genetic analysis and gene mapping of a new rolled-leaf mutant in rice (Oryza sativa L.)显示文摘To understand the development of rice leaf blades,we identified a new rolled-leaf mutant,w32,from indica cultivar IR64 through EMS mutagenesis. The mutant showed a stable rolled-leaf phenotype throughout the life cycle. Two F2 populations were developed by crossing w32 to cultivar IR24 and PA64. Genetic analysis showed that the rolled-leaf phenotype was controlled by a single recessive gene. To determine the location of the gene,bulked segregant analysis was carried out using mutant and wild-type DNA pools and 1846 mutant-type F2 individuals derived from the cross w32/PA64 were genotyped to locate the gene on the short arm of chromosome 7. The rolled-leaf gene,tentatively named rl11(t),is likely a new gene as no other rolled-leaf genes have been identified near the region. By developing new SSR and InDel markers,the gene was delimited to a 52 kb region near the end of the short chromosome arm. Further fine mapping and cloning of the gene are currently underway.SHI YongFeng1,2,CHEN Jie1,LIU WenQiang1,HUANG QiNa1,2,SHEN Bo2,LEUNG Hei3 & WU JianLi1 1 Chinese National Center for Rice Improvement/National key Laboratory for Rice Biology,China National Rice Research Institute,Hangzhou 310006,China 2 College of Life and Environmental Sciences,Hangzhou Normal University,Hangzhou 310016,China 3 International Rice Research Institute,Metro Manila DAPO Box 7777,Philippines 2009Science China(Life Sciences)2009,52,9:29
3城市轨道交通2015年统计和分析显示文摘截至2015年末,中国大陆地区共26座城市开通城市轨道交通运营线路总长度达3 618 km,新增445 km,全年累计完成客运量138亿人次,完成投资3 683亿元,在建线路总长4 448 km,44座城市规划获批,规划规模4 705 km。统计城市轨道交通运营、在建、规划的基础数据,通过数据的分析比对,给出全国城市轨道交通行业的整体发展情况和趋势分析,对'十二五'期间的发展进行总结并对'十三五'进行展望,同时基于统计分析提出行业发展的几点思考和建议。China Association of Metros 2016都市快轨交通2016,0,4:22
4Interactions among Micronutrient Deficiencies and Undernutrition in the Philippines显示文摘Data gathered from the 1987 National Nutrition Survey in the Philippines provided the opportunity to study the interactions among micronutrient deficiencies and undernutrition in different age groups as basis for program targeting. A randomly selected set of 50% of the households (3,200) covered by the national survey served as source of subjects. Results showed that there was a greater proportion of anemia among the undernourished (as judged by weight for age in children and weight for height in adults) (66.0%)than among the adequately nourished (54.6%) (P <0.01 ). However, the observed differencesin the proportion of serum vitamin A deficiency and of goiter among the undernourished compared to the adequately nourished were not significant. Also not significant were the observed higher prevalence of anemia among subjects with acceptable serum vitamin A levels for both adequately nourished and undernourished, and the higher prevalence of vitamin A deficiency among the non-anemics. Again there were no significant differences in the prevalence of anemia among goitrous and non-goitrous subjects, as well as the prevalence of goiter among anemic and non-anemic subjects. Neither were there significant differences in the prevalence of vitamin A deficiency among goitrous and non-goitrous subjects, but there were significant differences in the prevalence of goiter among vitamin A deficient and non-vitamin A defjcient subjects among the 7-14 years old and among pregnant and lactating women.The study concludes that at the national level, there is apparently an interaction between anemia and protein-energy undernutrition and possibly also between goiter and vitamin A deficiency in the high-risk age groups, but between anemia on the one hand and goiter and vitamin A deficiency in the other, perhaps because of clustering in the latter conditions not found in anemia and general undernutrition. These findings may be useful in targeting communities with high prevalence of micronutrient deficiencies by using prevalence of underweight and goiter as indicators for high prevalence of anemia and vitamin A deficiency,R. F. FLORENTINO C. C. TANCHOCO M. P. RODRIGUEZ A. J. CRUZ AND W. L. MOLANO(Food and Nutrition Research Insititute-Department of Science and Technology Science Compound Bicutan, Tagig, Metro Manila, Philippines) 1996Biomedical and Environmental Sciences1996,9,2:2
5EGFR,HER2,and phospho-Akt are not predictive factors for response to first-line chemotherapy in patients with advanced non-small cell lung cancer (NSCLC)显示文摘Toschi L Metro G Magrini E 2006J Clin Oncol2006,24,18:1
6Impact of specific mutant KRAS on clinical outcome of EGFR-TKI-treated advanced non-small cell lung cancer patients with an EGFR wild type genotype显示文摘Metro G Chiari R Duranti S 2012Lung Cancer2012,78,1:1
7Treatment of recurrent malig- nant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation显示文摘Fabi A Metro G Russillo M 2009BMC Cancer2009,31,9:1
8Carboplatin plus pemetrexed for plat- inum-pretreated ,advanced non-small cell lung cancer: a retrospective study with pharmacogenetic evaluation显示文摘Metro G Chiari R Mare M 2011Cancer Chemother Pharmacol2011,68,6:1
9Epidermal growth factor receptor (EGFR) targeted therapies in non-small cell lung cancer (NSCLC) 显示文摘Metro G Finocchiaro G Toschi L 2006Rev Recent Clin Trials2006,1,1:1
10Taxanes and gemcitabine doublets in the management of HER-2 negative metastatic breast cancer:towards optimization of association and schedule 显示文摘Metro G Fabi A Russillo M 2008Anticancer Res2008,28,2:1
11Chaperone-mediated inhibition of tubulin self-assembly显示文摘Metro G Saba A Gupta T D 2007Proteins2007,67,1:1
12An- giomyolipoma of the renal sinus: diagnosis by percuta- neous biopsy显示文摘Metro M J Ramchandani P Banner M P 2000Urology2000,55,2:1
13Treatment of recurrentmalignant gliomas with fotemustine monotherapy: impact ofdose and correlation with MGMT promoter methylation显示文摘Fabi A Metro G Russillo M 2009BMCCancer2009,9,:1
14Development of gemciabine in non-small cell lung cancer:the Italian contribution显示文摘Metro G Cappuzzo F Finocchiaro G 2006Annals of Oncology2006,17,5:1
15Emerging drugs for small - cell lung cancer 显示文摘Metro G Cappuzzo F 2009Expert Opin Emerging Drugs2009,14,4:1
16Clinical significance of PTEN and p-Akt co- expression in HER2-positive metastatic breast cancer patients treated with trastuzumab- based therapies 显示文摘Fabi A Metro G Di Benedetto A 2010Oncology2010,78,2:1
17Lifetime portfolio selection under uncertainty:the continuous time model显示文摘METRO R C 1969The review of economics and statistics1969,51,3:1
18Brain metastases from solid tumors: disease outcome according to type of treatment and therapeutic resources of the treating center显示文摘Fabi A Felici A Metro G 2011J Exp Clin Cancer Res2011,30,:1
19Carboplatin plus pemetrexed for platinum-pretreated, advanced non-small cell lung cancer: a retro- spective study with pharmacogenctic cvaluatian 显示文摘Metro G Chiari R Mare M 2011Cancer Che- mother Pharmaco12011,68,6:1
20Epidermal growth factor receptor (EGFR) targeted therapies in non-small cell lung cancer (NSCLC) 显示文摘Metro G Finocchiaro G Toschi L 2006Rev Recent Clin Trials2006,1,1:1
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