维普中文期刊产品整合服务
5篇 您的检索式:作者名="Michael J. Forster"
    题名 作者 年代 出处 被引量
1Mitochondrial protein sulfenation during aging in the rat brain显示文摘There is accumulating evidence that cysteine sulfenation (cys-SOH) in proteins plays an important rolein cellular response to oxidative stress. The purpose of the present study was to identify mitochondrialproteins that undergo changes in cys-SOH during aging. Studies were conducted in rats when they were5 or 30 months of age. Following blocking of free protein thiols with N-ethylmaleimide, protein sulfenicacids were reduced by arsenite to free thiol groups that were subsequently labeled with biotin-maleimide. Samples were then comparatively analyzed by two-dimensional Western blots, and proteinsshowing changes in sulfenation were selectively identified by mass spectrometry peptide sequencing.As a result, five proteins were identified. Proteins showing an age-related decrease in sulfenationinclude pyruvate carboxylase and pyruvate dehydrogenase; while those showing an age-relatedincrease in sulfenation include aconitase, mitofilin, and tubulin (α-1). Results of the present studyprovide a general picture of mitochondrial protein sulfenation in brain oxidative stress and implicatethe involvement of protein sulfenation in overall decline of mitochondrial function during brain aging.Xiaorong Yang Jinzi Wu Siqun ling Michael J. Forster Liang-Jun Yan 2018Biophysics Reports2018,4,2:3
2Effects of age and caloric restriction on mitochondrial protein oxidative damage in mice显示文摘Xiao-Dong Li Igor Rebrin Michael J. Forster Rajindar S. Sohal 2011Mechanisms of Ageing and Development2011,,1:1
3Isolation of a sequence common to A- and B-chromosomes of rye (Secale cereale) by microcloning显示文摘Michael J. Sandery John W. Forster Simon R. Macadam Richard Blunden R. Neil Jones Stephen D. M. Brown 1991Plant Molecular Biology Reporter1991,,1:1
4Isolation of a sequence common to A- and B-chromosomes of rye (Secale cereale) by microcloning显示文摘Michael J. Sandery John W. Forster Simon R. Macadam Richard Blunden R. Neil Jones Stephen D. M. Brown 1991Plant Molecular Biology Reporter1991,,1:1
5Isolation of a sequence common to A- and B-chromosomes of rye (Secale cereale) by microcloning显示文摘Michael J. Sandery John W. Forster Simon R. Macadam Richard Blunden R. Neil Jones Stephen D. M. Brown 1991Plant Molecular Biology Reporter1991,,1:1
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费