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1篇 您的检索式：作者名="MichaelP.Waalkes"

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		题名	作者	年代	出处	被引量
	1	Expression of cyclooxygenase-2 in human esophageal squamous cell carcinomas显示文摘AIM: To determine whether cyclooxygenase-2 (COX-2) wasm expressed in human esophageal squamous cell carcinoma.METHODS: Quantitative reverse transcription-polymerase chain reaction (RT-PCR), western blotting, immunohistochemistry and immunofluorescence were used to assess the expression level of COX-2 in esophageal tissue.RESULTS: COX-2 mRNA levels were increased by >80-fold in esophageal squamous cell carcinoma when compared to adjacent noncancerous tissue. COX-2 protein was present in 21 of 30 cases of esophageal squamous cell carcinoma tissues, but was undetectable in noncancerous tissue. Immunohistochemistry was performed to directlyshow expression of COX-2 in tumor tissue.CONCLUSION: These results suggest that COX-2 may be an important factor for esophageal cancer and inhibition of COX-2 may be helpful for prevention and possibly treatment of this cancer.	Jian-GangJiang Jiang-BoTang Chun-LianChen Bao-XingLiut Xiang-NingFu Zhi-HuiZhu WeiQu KatherineCianflone MichaelP.Waalkes Dao-WenWang	2004	World Journal of Gastroenterology2004，10，15：	12

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