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| 1 | The dynamics of the piglet gut microbiome during the weaning transition in association with health and nutrition显示文摘Background: Understanding the composition of the microbial community and its functional capacity during weaning is important for pig production as bacteria play important roles in the pig's health and growth performance. However,limited information is available regarding the composition and function of the gut microbiome of piglets in early-life.Therefore, we performed 16 S rRNA gene and whole metagenome shotgun sequencing of DNA from fecal samples from healthy piglets during weaning to measure microbiome shifts, and to identify the potential contribution of the early-life microbiota in shaping piglet health with a focus on microbial stress responses, carbohydrate and amino acid metabolism.Results: The analysis of 16 S rR NA genes and whole metagenome shotgun sequencing revealed significant compositional and functional differences between the fecal microbiome in nursing and weaned piglets. The fecal microbiome of the nursing piglets showed higher relative abundance of bacteria in the genus Bacteroides with abundant gene families related to the utilization of lactose and galactose. Prevotel a and Lactobacil us were enriched in weaned piglets with an enrichment for the gene families associated with carbohydrate and amino acid metabolism. In addition, an analysis of the functional capacity of the fecal microbiome showed higher abundances of genes associated with heat shock and oxidative stress in the metagenome of weaned piglets compared to nursing piglets.Conclusions: Overal, our data show that microbial shifts and changes in functional capacities of the piglet fecal microbiome resulted in potential reductions in the effects of stress, including dietary changes that occur during weaning.These results provide us with new insights into the piglet gut microbiome that contributes to the growth of the animal. | Robin B.Guevarra Sang Hyun Hong Jin Ho Cho Bo-Ra Kim Jiwon Shin Jun Hyung Lee Bit Na Kang Young Hwa Kim Suphot Wattanaphansak Richard E.Isaacson Minho Song Hyeun Bum Kim | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 16 |
| 2 | Supplementation of different fat sources affects growth performance and carcass composition of finishing pigs显示文摘Background: There are various fat sources with different energy values and fatty acid compositions that may affect growth performance and carcass composition of grow-finishing pigs. A higher net energy was recently reported in choice white grease compared with soybean oil. Therefore, two experiments were conducted to determine whether practical responses confirm that difference between choice white grease and soybean oil, and to extend the observations to other fat sources.Results: In Exp. 1, pigs fed fats had lower(P < 0.05) average daily feed intake in phase II and overall period,greater(P < 0.05) gain:feed in phase I, phase II, and overall period than pigs fed the control diet. Pigs fed fats tended(P = 0.057) to have thicker backfat depth at the last rib than those fed control. Pigs fed 6% fats had greater(P < 0.01) gain:feed in phase II and overall period than pigs fed 3% fats. During phase I, pigs fed choice white grease grew faster(P < 0.05) than pigs fed soybean oil. In Exp. 2, pigs fed dietary fats(soybean oil, choice white grease, animal-vegetable blend, palm oil, or tallow) had greater(P < 0.01) gain:feed in each phase and overall period, greater(P < 0.01) average daily gain in phase I, but lower(P < 0.01) average daily feed intake in phase II an overall than pigs fed the control diets. The choice white grease also increased(P < 0.05) average daily gain during phase I compared with soybean oil. Pigs fed palm oil had thicker(P < 0.05) backfat depth at the 10 thrib than those fed soybean oil, animal-vegetable blend, or tallow.Conclusions: Inclusion of 6% dietary fat improved feed efficiency of finishing pigs, while different fats produced different practical results that may be consistent with their different energy values. Results from the early stage indicate that dietary fats with relatively more saturated fatty acids may provide greater energy than those with relatively more unsaturated fatty acids for growing pigs. | Yanhong Liu Dong Yong Kil Victor G.Perez-Mendoza Minho Song James E.Pettigrew | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 5 |
| 3 | Simultaneous Measurement of Temperature and Strain Using Two Fiber Bragg Gratings Embedded in a Glass Tube显示文摘 | Minho Song | 1997 | Optical Fiber Technology1997，，3： | 1 |
| 4 | A robust global optimization algorithm of electromagnetic devices utilizing gradient index and multi-objective optimization method显示文摘 | Ren Ziyan Pham Minh-Trien Song Minho Kim Dong-Hun Koh Chang Seop | 2011 | IEEE Transactions on Magnetics2011，47，5： | 1 |
| 5 | Fiber Bragg grating strain sensor demodulation with quadrature sampling of a Mach- Zehnder interferometer 显示文摘 | Song Minho Yin Shizhuo Ruffin Paul B | 2000 | Appl Opt2000，39，7： | 1 |
| 6 | Escherichia coli challenge and one type of smectite alter intestinal barrier of pigs显示文摘An experiment was conducted to determine how an E. coli challenge and dietary clays affect the intestinal barrier of pigs. Two groups of 32 pigs(initial BW: 6.9 土 1.0 kg) were distributed in a 2 x 4 factorial arrangement of a randomized complete block design(2 challenge treatments: sham or ￡ coli, and 4 dietary treatments: control, 0.3%smectite A, 0.3% smectite B and 0.3% zeolite), with 8 replicates total. Diarrhea score, growth performance, goblet cell size and number, bacterial translocation from intestinal lumen to lymph nodes, intestinal morphology, and relative amounts of sulfo and sialo mucins were measured. The ￡ coli challenge reduced performance, increased goblet cell size and number in the ileum, increased bacterial translocation from the intestinal lumen to the lymph nodes, and increased ileal crypt depth. One of the clays(smectite A) tended to increase goblet cell size in ileum,which may indicate enhanced protection. In conclusion, ￡ coli infection degrades intestinal barrier integrity but smectite A may enhance it. | Juliana Abranches Soares Almeida Yanhong Liu Minho Song Jeong Jae Lee H Rex Gaskins Carol Wolfgang Maddox Orlando Osuna James Eugene Pettigrew | 2014 | Journal of Animal Science and Biotechnology2014，5，2： | 1 |
| 7 | Intracellular Amyloid-β Accumulation in Calcium-Binding Protein-Deficient Neurons Leads to Amyloid-β Plaque Formation in Animal Model of Alzheimer’s Disease显示文摘 | Minho Moon Hyun-Seok Hong Dong Woo Nam Sung Hoon Baik Hyundong Song Sun-Young Kook Yong Soo Kim Jeewoo Lee Inhee Mook-Jung | 2011 | Journal of Alzheimer’s Disease2011，，3： | 1 |
| 8 | Surface profile measurement using a unique microtube-based system 显示文摘 | Li Jiang Song Minho | 1999 | Optics Communications1999，168，： | 1 |
| 9 | Fiber Bragg grating strain sensor demodulation with quadrature sampling of a Mach-Zehnder interferometer显示文摘 | Song Minho Yin Shizhuo Ruffin Paul B | 2000 | Appl Opt2000，38，： | 1 |
| 10 | Dietary plant extracts modulate gene expression profiles in alveolar macrophages of pigs experimentally infected with porcine reproductive and respiratory syndrome virus显示文摘Background: Our previous study showed that 3 plant extracts enhanced the immune responses and growth efficiency of weaned pigs infected with porcine reproductive and respiratory syndrome virus(PRRSV), which is one of the most economically important disease in swine industry. However, each plant extract differently effected on growth efficiency and immune responses. Therefore, the objective of this study was conducted to characterize the effects and investigate the potential underlying mechanisms of 3 plant extracts on gene expression of alveolar macrophages in weaned pigs experimentally infected with PRRSV.Results: PRRSV infection altered(P < 0.05) the expression of 1,352 genes in pigs fed the control(CON;755 up, 597 down). Compared with the infected CON, feeding capsicum(CAP), garlic botanical(GAR), or turmeric oleoresin(TUR) altered the expression of 46 genes(24 up, 22 down), 134 genes(59 up, 75 down), or 98 genes(55 up, 43 down) in alveolar macrophages of PRRSV-infected pigs, respectively. PRRSV infection up-regulated(P < 0.05) the expression of genes related to cell apoptosis, immune system process, and response to stimulus, but downregulated(P < 0.05) the expression of genes involved in signaling transduction and innate immune response.Compared with the infected CON, feeding TUR or GAR reduced(P < 0.05) the expression of genes associated with antigen processing and presentation, feeding CAP up-regulated(P < 0.05) the expression of genes involved in antigen processing and presentation. Supplementation of CAP, GAR, or TUR also enhanced(P < 0.05) the expression of several genes related to amino acid metabolism, steroid hormone synthesis, or RNA degradation, respectively.Conclusions: The results suggest that 3 plant extracts differently regulated the expression of genes in alveolar macrophages of PRRSV-infected pigs, especially altering genes involved in immunity. | Kwangwook Kim Peng Ji Minho Song Tung M.Che David Bravo James E.Pettigrew Yanhong Liu | 2021 | Journal of Animal Science and Biotechnology2021，12，1： | 0 |
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