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| 1 | Adaptive and responsive surfaces through controlled reorganization of interracial polymer layers 显示文摘 | Luzinov I Minko S Tsukruk V V | 2004 | Progress in Polymer Science2004,29,: | 1 |
| 2 | Direct measurement of thermoelastic properties of glassy and rubbery polymer brush nanolayers grown by 'grafting-from' approach 显示文摘 | Lemieux M Minko S Usov D | 2003 | Langmuir2003,19,15: | 1 |
| 3 | Remote Control of Extended Depth of Field Focusing显示文摘 | Brahim Chebbi Sergey Minko Nezar Al Akwaa | 2010 | Optics Communications2010,283,9: | 1 |
| 4 | Polymer-drug conjugates:progress inpolymeric prodrugs显示文摘 | Khandare J Minko T | 2006 | Prog Polym Sci2006,31,4: | 1 |
| 5 | Migraine in the Andes and headache at sea level 显示文摘 | Appenzeller O Minko T Qalls C | 2005 | Cephalalgia2005,25,12: | 1 |
| 6 | Enhancing the anticancer efficacy of camptothecin using biotinylated poly(ethylene glycol)conjugates in sensitive and multidrug-resistant human ovarian carcinoma cells 显示文摘 | Minko T Paranjpe PV Qiu B | 2002 | Cancer Chemother Pharmacol2002,50,2: | 1 |
| 7 | Targeted proapoptotic LHRH-BH3 peptide显示文摘 | Dharap SS Minko T | 2003 | Pharm Res2003,20,6: | 1 |
| 8 | Drug targeting to the colon with leetins and neo - glycoconju- gates 显示文摘 | Minko T | 2004 | Advaneed Drug Delivery Reviews2004,56,4: | 1 |
| 9 | Mole- cular targeting of drug delivery systems to cancer显示文摘 | Minko T Dharap S Pakunlu RI | 2004 | Current Drug Targets2004,5,4: | 1 |
| 10 | Multifunctional triblock nano- carrier(PAMAM-PEG-PLL) for the efficient intracellulai' siRNA delivery and gene silencing 显示文摘 | PATIL ML ZHANG M MINKO T | 2011 | ACS Nano2011,5,3: | 1 |
| 11 | Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer显示文摘 | Saad M Garbuzenko OB Minko T | 2008 | Nanomedicine (Lond)2008,3,6: | 1 |
| 12 | Drug targeting to the colon with lectins and neoglycoconjugates显示文摘 | T Minko | | 0,,04: | 1 |
| 13 | Polymer-drug conjugates:Progress in polymeric prodrugs显示文摘 | Jayant Khandare Tamara Minko | 2006 | 31(4):3592006,31,4: | 1 |
| 14 | HPMA copolymer±anticancer drug conjugates: design, activity, and mechanism of action显示文摘 | Kopecek J Kopec-kova P Minko T | 2000 | European Journal of Pharmaceutics and Biopharmaceutics2000,50,: | 1 |
| 15 | HPMA copolymer bound anticancer drug mechanism of action on cellular and subcellular levels 显示文摘 | Kopeckoya P Minko T | 1999 | Prog Int Symp Cont rolled Rel Bioact Mater1999,26,1: | 1 |
| 16 | The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase 显示文摘 | VARTANIAN V LOWELL B MINKO I G | 2006 | Proc NatlAcadSci USA2006,103,6: | 1 |
| 17 | Co-delivery of Doxorubicin and Bcl-2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug Resistant Cancer Cells显示文摘 | Alex Chen Min Zhang Dongguang Wei Dirk Stueber Oleh Taratula Tamara Minko Huixin He | | 0,,23: | 1 |
| 18 | Stimuli-responsivehydrogelthinfilms显示文摘 | TokarevI MinkoS | 2009 | SoftMatter2009,5,: | 1 |
| 19 | Vent sizing: analysis of the blowdown of a hybrid non tempered system 显示文摘 | VECHOT L MINKO W BIGOT J P | 2011 | Journal of Hazardous Materials2011,191,123: | 1 |
| 20 | Inhalation treatment of lung cancer: the influence of composition, size and shape of nanocarriers on their lung accumulation and retention显示文摘Objective: Various nanoparticles have been designed and tested in order to select optimal carriers for the inhalation delivery of anticancer drugs to the lungs. Methods: The following nanocarriers were studied: micelles, liposomes, mesoporous silica nanoparticles(MSNs), poly propyleneimine(PPI) dendrimer-siRNA complexes nanoparticles, quantum dots(QDs), and poly(ethylene glycol) polymers. All particles were characterized using the following methods: dynamic light scattering, zeta potential, atomic force microscopy, in vitro cyto- and genotoxicity. In vivo organ distribution of all nanoparticles, retention in the lungs, and anticancer effects of liposomes loaded with doxorubicin were examined in nude mice after the pulmonary or intravenous delivery. Results: Significant differences in lung uptake were found after the inhalation delivery of lipid-based and non-lipid-based nanoparticles. The accumulation of liposomes and micelles in lungs remained relatively high even 24 h after inhalation when compared with MSNs, QDs, and PPI dendrimers. There were notable differences between nanoparticle accumulation in the lungs and other organs 1 and 3 h after inhalation or intravenous administrations, but 24 h after intravenous injection all nanoparticles were mainly accumulated in the liver, kidneys, and spleen. Inhalation delivery of doxorubicin by liposomes significantly enhanced its anticancer effect and prevented severe adverse side effects of the treatment in mice bearing the orthotopic model of lung cancer.Conclusion: The results of the study demonstrate that lipid-based nanocarriers had considerably higher accumulation and longer retention time in the lungs when compared with non-lipid-based carriers after the inhalation delivery. These particles are most suitable for effective inhalation treatment of lung cancer. | Olga B.Garbuzenko Gediminas Mainelis Oleh Taratula Tamara Minko | 2014 | Cancer Biology & Medicine2014,11,1: | 1 |