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128篇 您的检索式:作者名="MinkoS"
    题名 作者 年代 出处 被引量
1Adaptive and responsive surfaces through controlled reorganization of interracial polymer layers 显示文摘Luzinov I Minko S Tsukruk V V 2004Progress in Polymer Science2004,29,:1
2Direct measurement of thermoelastic properties of glassy and rubbery polymer brush nanolayers grown by 'grafting-from' approach 显示文摘Lemieux M Minko S Usov D 2003Langmuir2003,19,15:1
3Remote Control of Extended Depth of Field Focusing显示文摘Brahim Chebbi Sergey Minko Nezar Al Akwaa 2010Optics Communications2010,283,9:1
4Polymer-drug conjugates:progress inpolymeric prodrugs显示文摘Khandare J Minko T 2006Prog Polym Sci2006,31,4:1
5Migraine in the Andes and headache at sea level 显示文摘Appenzeller O Minko T Qalls C 2005Cephalalgia2005,25,12:1
6Enhancing the anticancer efficacy of camptothecin using biotinylated poly(ethylene glycol)conjugates in sensitive and multidrug-resistant human ovarian carcinoma cells 显示文摘Minko T Paranjpe PV Qiu B 2002Cancer Chemother Pharmacol2002,50,2:1
7Targeted proapoptotic LHRH-BH3 peptide显示文摘Dharap SS Minko T 2003Pharm Res2003,20,6:1
8Drug targeting to the colon with leetins and neo - glycoconju- gates 显示文摘Minko T 2004Advaneed Drug Delivery Reviews2004,56,4:1
9Mole- cular targeting of drug delivery systems to cancer显示文摘Minko T Dharap S Pakunlu RI 2004Current Drug Targets2004,5,4:1
10Multifunctional triblock nano- carrier(PAMAM-PEG-PLL) for the efficient intracellulai' siRNA delivery and gene silencing 显示文摘PATIL ML ZHANG M MINKO T 2011ACS Nano2011,5,3:1
11Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer显示文摘Saad M Garbuzenko OB Minko T 2008Nanomedicine (Lond)2008,3,6:1
12Drug targeting to the colon with lectins and neoglycoconjugates显示文摘T Minko 0,,04:1
13Polymer-drug conjugates:Progress in polymeric prodrugs显示文摘Jayant Khandare Tamara Minko 200631(4):3592006,31,4:1
14HPMA copolymer±anticancer drug conjugates: design, activity, and mechanism of action显示文摘Kopecek J Kopec-kova P Minko T 2000European Journal of Pharmaceutics and Biopharmaceutics2000,50,:1
15HPMA copolymer bound anticancer drug mechanism of action on cellular and subcellular levels 显示文摘 Kopeckoya P Minko T 1999Prog Int Symp Cont rolled Rel Bioact Mater1999,26,1:1
16The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase 显示文摘VARTANIAN V LOWELL B MINKO I G 2006Proc NatlAcadSci USA2006,103,6:1
17Co-delivery of Doxorubicin and Bcl-2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug Resistant Cancer Cells显示文摘Alex Chen Min Zhang Dongguang Wei Dirk Stueber Oleh Taratula Tamara Minko Huixin He 0,,23:1
18Stimuli-responsivehydrogelthinfilms显示文摘TokarevI MinkoS 2009SoftMatter2009,5,:1
19Vent sizing: analysis of the blowdown of a hybrid non tempered system 显示文摘VECHOT L MINKO W BIGOT J P 2011Journal of Hazardous Materials2011,191,123:1
20Inhalation treatment of lung cancer: the influence of composition, size and shape of nanocarriers on their lung accumulation and retention显示文摘Objective: Various nanoparticles have been designed and tested in order to select optimal carriers for the inhalation delivery of anticancer drugs to the lungs. Methods: The following nanocarriers were studied: micelles, liposomes, mesoporous silica nanoparticles(MSNs), poly propyleneimine(PPI) dendrimer-siRNA complexes nanoparticles, quantum dots(QDs), and poly(ethylene glycol) polymers. All particles were characterized using the following methods: dynamic light scattering, zeta potential, atomic force microscopy, in vitro cyto- and genotoxicity. In vivo organ distribution of all nanoparticles, retention in the lungs, and anticancer effects of liposomes loaded with doxorubicin were examined in nude mice after the pulmonary or intravenous delivery. Results: Significant differences in lung uptake were found after the inhalation delivery of lipid-based and non-lipid-based nanoparticles. The accumulation of liposomes and micelles in lungs remained relatively high even 24 h after inhalation when compared with MSNs, QDs, and PPI dendrimers. There were notable differences between nanoparticle accumulation in the lungs and other organs 1 and 3 h after inhalation or intravenous administrations, but 24 h after intravenous injection all nanoparticles were mainly accumulated in the liver, kidneys, and spleen. Inhalation delivery of doxorubicin by liposomes significantly enhanced its anticancer effect and prevented severe adverse side effects of the treatment in mice bearing the orthotopic model of lung cancer.Conclusion: The results of the study demonstrate that lipid-based nanocarriers had considerably higher accumulation and longer retention time in the lungs when compared with non-lipid-based carriers after the inhalation delivery. These particles are most suitable for effective inhalation treatment of lung cancer.Olga B.Garbuzenko Gediminas Mainelis Oleh Taratula Tamara Minko 2014Cancer Biology & Medicine2014,11,1:1
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