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| 1 | Low concentrations of the recombinant toxin protein rLj-RGD3 suppress TNF-a-induced human renal carcinoma cell invasion显示文摘肾的房间癌(RCC ) 的一个特点侵略由 gelatinase 酶的本地生产是细胞外的矩阵(ECM ) 的降级。矩阵 metalloproteinase-9 (MMP-9 ) 导致了癌症房间侵略是在癌症的枢轴的步之一转移。它被报导了那个肿瘤坏死因素 --(TNF-) , MMP-9 的一个管理者,能在人的肾的癌房间导致侵略。在我们的实验室的以前的工作显示出那 rLj-RGD3,从 Lampetra 装饰用的梨树的口腔的腺分泌物的 recombinant RGD (ArgGlyAsp ) 毒素蛋白质,拥有反肿瘤活动。在这研究,我们证明 rLj-RGD3 压制了 TNF -- 在 786-0 房间(人的肾的癌房间) 的导致的 MMP-9 分泌物。在 TNF 上调查 rLj-RGD3 的规章的效果 -- 导致的 MMP-9 分泌物,我们预先对待有 rLj-RGD3 的房间。有趣地, rLj-RGD3 没在 MMP 的组成的分泌物上有重要效果。然而, rLj-RGD3 的低集中减少了 TNF -- 导致的 MMP-9 分泌物。功能的研究表明 rLj-RGD3 导致了 apoptosis 并且显著地禁止了 786-0 房间的增长,迁居,和侵略。而且,在房间的肌动朊建筑学与 rLj-RGD3 预先对待被聚集并且瓦解。我们的调查结果建议 rLj-RGD3 可以在肾的癌症被用作潜在的药治疗。 | Minli Jin Rong Xiao Jihong Wang Xin Liu Yu Liu Zhuang Xue Li Lv Yuanyuan Zheng Qingwei Li | 2013 | Acta Biochimica et Biophysica Sinica2013，45，5： | 2 |
| 2 | Discovering patterns to extract protein-protein interactions from full texts 显示文摘 | Huang Minlie Zhu Xiaoyan Hao Yu | 2004 | Bioinformatics2004，20，18： | 1 |
| 3 | Discovering patterns to extract protein-protein interactions from the literature : Part Ⅱ 显示文摘 | Hao Yu Zhu Xiaoyan Huang Minlie | 2005 | Bioinformaties2005，21，15： | 1 |
| 4 | Discoveringpatterns to extract protein-protein interactions from full texts显示文摘 | HUANG Minlie ZHU Xiaoyan HAO Yu | 2004 | Bioinformatics2004，20，18： | 1 |
| 5 | Different enhancement of senescence induced by metabolic products of Alternaria alternata in tobacco leaves of different ages显示文摘 | Yu‐JiaoJia Dan‐DanCheng Wei‐BinWang Hui‐YuanGao Ai‐XinLiu Xin‐MinLi Qing‐WeiMeng | 2010 | Physiologia Plantarum2010，，2： | 1 |
| 6 | Discovering patterns to extract protein-protein interactions from full texts显示文摘 | Huang Minlie Zhu Xiaoyan Hao Yu | 2004 | Bioinformati-cs2004，20，18： | 1 |
| 7 | CLINICAL ANALYSIS OF EARLY POSTINFARCTION ISCHEMIA BY AMBULATORY ELECTROCARDIOGRAPHIC MONITORING显示文摘Objective:To study clinical significance of early postinfarctionischemia by ambulatory electrocardiographic monitoring(AEM).Methods:There were 64 petients with acute myocardial infarction(AMI).43 males,21 females,with a mean age of 61 years.Among of them,31 were anteriormyocardial infarction(MI),26 were inferior HI,7 were HI with botbanterior and inferior,All patlents were contintinueouslyonitored for5-12 days,The judging criteria were①ST segment depressed≥0.1andlasted for≥1 minute②The time interval between two ischemia attacks>1 minute.Results:Of all patients,46 showed postinfarction ischemia(PII)(72%),17 of them with symptom of postinfarction angina(PIA)(37%),29 of them without any symptom(63%).The incidence of PII within a weekafter infarction is 83%.These patients’incidence of arrhythimia,heartfallure,and cardiogenic shock are 90.24%,68.29%,and 19.51% respective-ly,which are much higher than that of those without PII attack.Discussion:The occurrence of PIA indicates relapsing myocardialischemia,and coronary angiography has confirmed a great degree ofstenosis with coronary artery.The exist of PII is one of theIndependent dan factors of bad prognosis of coronary heartdisease.It has been confirmed by other articles that ischemis mayexist whether PIA occurs or not,and the ircidence of ischemia withoutsymptom is higher,having the same result with this one.The depressionof ST segment can sensltively show ischemia So we must pay attentionto the change of ST segment in early stage of AMI.By AEM,we can findthat PII has different appearances and incidence with differentinfarction position and infarction range,and its occurrence has timedistribution,part of them are related to the activities of patients.Ischemia occurs more frequently in patients with anterior HI thanthose with inferior MI.The more extensive infarction,the higherincidence of ischemia,and the incidence of all kinds of complicationsand the mortality rate are higher in those with PII than those withoutit.Weiner D.A etc.also had similar reports.So we must strengthen themonitoring to the patients with PII to lay out individual cure planaccording to different attack characteristics,when necessary,we shouldtake coronary angiography to make PTCA or CABG. | Minli Zhao Yu Zhong.The Third Hospital of Tangshan,063100,China. | 1998 | 中国介入心脏病学杂志1998，6，4： | 1 |
| 8 | Digital finance and renewable energy consumption:evidence from China显示文摘While digital finance and renewable energy consumption(REC)are two timely issues,it remains unclear whether the former affects the latter,especially in developing economies.This paper examines the impact of digital finance on China’s REC between 2011 and 2018 and explores the underlying mechanisms.Results show that digital finance,along with its coverage breadth and usage depth,significantly improved REC in China and that digital finance in the area of credit has had the most significant impact.Additionally,the results show that loan scale and income level are the main mediation variables,through which digital finance affects REC.The findings also suggest that economic growth and technological progress have increased REC in China,while carbon dioxide emissions have had no meaningful effect on this consumption.The results further indicate that policymakers must pay close attention to the role of digital finance when formulating policies on REC.To promote REC and environmental sustainability,developing economies like China should strengthen the breadth and depth of digital finance development,focus on the influence channels of digital finance,and promote economic growth and technological progress. | Minli Yu Fu-Sheng Tsai Hui Jin Hejie Zhang | 2022 | Financial Innovation2022，8，1： | 0 |
| 9 | In vivo effects of neomycin sulfate on non-specific immunity,oxidative damage and replication of cyprinid herpesvirus 2 in crucian carp(Carassius auratus gibelio)显示文摘Neomycin belongs to the family of 2-deoxystreptamine-containing aminoglycoside antibiotics.It is widely used for bacterial infections,targeting most gram-negative and some gram-positive bacteria.Neomycin has also been reported to show antiviral activity.Here,we evaluated the toxicity of neomycin sulfate,and investigated its effect on non-specific immunity and viral infection in crucian carp(Carassius auratus gibelio).The safe concentration of neomycin sulfate for crucian carp was determined to be 102.9 mg/kg in vivo.In oxidative damage assays,neomycin sulfate increased superoxide dismutase and catalase activity and decreased malondialdehyde in the liver of crucian carp.In non-specific blood immune assays,the white blood cell count and complement 3 content significantly increased after neomycin sulfate treatment,while no significant changes were observed in antibacterial or lysozyme activity.In a challenge test,neomycin sulfate protected the crucian carp from cyprinid herpesvirus 2(CyHV-2)infection and inhibited CyHV-2 replication.In cytotoxicity assays,low concentrations of neomycin sulfate had no cytotoxicity on cells from the fins of crucian carp.The results of the present study indicate that oral administration of neomycin sulfate reduced oxidative damage,enhanced immunity and provided protection against CyHV-2 in crucian carp. | Penghui Sun Fei Yu Jianfei Lu Minli Zhang Hao Wang Dan Xu Liqun Lu | 2019 | Aquaculture and Fisheries2019，4，2： | 0 |
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