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2篇 您的检索式：作者名="Minsoo Han"

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		题名	作者	年代	出处	被引量
	1	Rheology of Blends of a Thermotropic Liquid Crystalline Polymer with Polyphenylene Sulfide显示文摘	Minsoo Han Woo Nyon Kim David W Giles	2004	Polym Eng Sci2004，41，9：	1
	2	Role of small leucine zipper protein in hepatic gluconeogenesis and metabolic disorder显示文摘Hepatic gluconeogenesis is the central pathway for glucose generation in the body.The imbalance between glucose synthesis and uptake leads to metabolic diseases such as obesity,diabetes,and cardiovascular diseases.Small leucine zipper protein(sLZIP)is an isoform of LZIP and it mainly functions as a transcription factor.Although sLZIP is known to regulate the transcription of genes involved in various cellular processes,the role of sLZIP in hepatic glucose metabolism is not known.In this study,we investigated the regulatory role of sLZIP in hepatic gluconeogenesis and its involvement in metabolic disorder.We found that sLZIP expression was elevated during glucose starvation,leading to the promotion of phosphoenolpyruvate carboxylase and glucose-6-phosphatase expression in hepatocytes.However,sLZIP knockdown suppressed the expression of the gluconeogenic enzymes under low glucose conditions.sLZIP also enhanced glucose production in the human liver cells and mouse primary hepatic cells.Fasting-induced cyclic adenosine monophosphate impeded sLZIP degradation.Results of glucose and pyruvate tolerance tests showed that sLZIP transgenic mice exhibited abnormal blood glucose metabolism.These findings suggest that sLZIP is a novel regulator of gluconeogenic enzyme expression and plays a role in blood glucose homeostasis during starvation.	Minsoo Kang Sun Kyoung Han Suhyun Kim Sungyeon Park Yerin Jo Hyeryung Kang Jesang Ko	2021	Journal of Molecular Cell Biology2021，13，5：	0

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