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| 1 | Fermentative Production of Dihydroxyacetone by Acetobacter suboxydans ATCC 621显示文摘 | Koichi Nabe Nobuhiko Izuo Mitsuru Wada Ichiro Chibata | 1979 | J Ferment Technol1979，57，3： | 1 |
| 2 | On a grading system for beef marbling显示文摘 | Fumito Yoshikawa Kazuo Toraichi Koichi Wada Nobuyuki Ostu Hisroyasu Nakai Mitsuru Mitsumoto Kazuki Katagishi | 2000 | Pattern Recognition Letters2000，，12： | 1 |
| 3 | Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire (JOACMEQ): part 4. Establishment of equations for severity scores显示文摘 | Mitsuru Fukui Kazuhiro Chiba Mamoru Kawakami Shinichi Kikuchi Shinichi Konno Masabumi Miyamoto Atsushi Seichi Tadashi Shimamura Osamu Shirado Toshihiko Taguchi Kazuhisa Takahashi Katsushi Takeshita Toshikazu Tani Yoshiaki Toyama Kazuo Yonenobu Eiji Wada T | 2008 | Journal of Orthopaedic Science2008，，1： | 1 |
| 4 | An outcome measure for patients with cervical myelopathy: Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire (JOACMEQ): Part 1显示文摘 | Mitsuru Fukui Kazuhiro Chiba Mamoru Kawakami Shin-ichi Kikuchi Shin-ichi Konno Masabumi Miyamoto Atsushi Seichi Tadashi Shimamura Osamu Shirado Toshihiko Taguchi Kazuhisa Takahashi Katsushi Takeshita Toshikazu Tani Yoshiaki Toyama Eiji Wada Kazuo Yonenobu | 2007 | Journal of Orthopaedic Science2007，，3： | 1 |
| 5 | On a grading system for beef marbling显示文摘 | Fumito Yoshikawa Kazuo Toraichi Koichi Wada Nobuyuki Ostu Hisroyasu Nakai Mitsuru Mitsumoto Kazuki Katagishi | 2000 | Pattern Recognition Letters2000，，12： | 1 |
| 6 | Assistant skill in gastric endoscopic submucosal dissection using a clutch cutter显示文摘BACKGROUND A clutch cutter is a scissor-type knife used in endoscopic submucosal dissection(ESD)for gastrointestinal tract tumors.The assistant during the ESD using a clutch cutter(ESD-C)needs to rotate the device and grasp the target tissue appropriately;therefore,the assistant’s skill may affect the technical outcomes of ESD-C.AIM To determine how assistant skill level affected the technical outcomes of gastric ESD-C using an ex vivo porcine training model.METHODS In this pilot study,mock lesions of 15-30 mm in diameter were created in the middle or lower third of the porcine stomach.A total of 32 ESD-C procedures were performed by 16 trainees.Each trainee operator performed two ESD-C procedures;one ESD-C was assisted by an expert(ESD-C-E),and the other was assisted by a non-expert(ESD-C-NE).The total procedure time of the ESD was set as the primary outcome,and en bloc resection rate,complete procedure rate,perforation rate,and each procedure time/speed for mucosal incision or submucosal dissection were set as the secondary outcomes.In addition,we investigated factors associated with the difficulty of ESD including incompletion of ESD procedure,a long procedure time(≥20 min)or intraoperative perforation.RESULTS The median total procedure time of the ESD-C-E was significantly shorter than that of the ESD-C-NE(12.9 min vs 21.9 min,P=0.001).The en bloc resection rate was 100%in both groups.Complete resection rates of the ESD-C-E and ESD-C-NE groups were 100%and 93.8%,respectively.No intraoperative perforation was observed in both groups.In the multivariate analysis,assistant skill was significantly associated with the difficulty of ESD,with the highest odds ratio of 16.5.CONCLUSION Assistance by an expert is an important factor when trainees perform ESD-C procedures. | Mitsuru Esaki Toshiki Horii Ryoji Ichijima Masafumi Wada Seiichiro Sakisaka Shuichi Abe Naru Tomoeda Yusuke Kitagawa Kei Nishioka Yosuke Minoda Shinichi Tsuruta Sho Suzuki Hirotada Akiho Eikichi Ihara Yoshihiro Ogawa Takuji Gotoda | 2021 | World Journal of Gastrointestinal Surgery2021，13，2： | 1 |
| 7 | Efficacy of hybrid endoscopic submucosal dissection with SOUTEN in gastric lesions:An ex vivo porcine model basic study显示文摘BACKGROUND Hybrid endoscopic submucosal dissection(ESD)that comprises mucosal incision and partial submucosal dissection followed by snaring in a planned manner,has been developed for endoscopic resection of gastrointestinal neoplasms to overcome the technical barrier of ESD.Although the superiority of hybrid ESD with SOUTEN,a single multifunctional device,over conventional ESD has been indicated,the actual effect of snaring itself remains unclear since SOUTEN could be applied to hybrid ESD group,but not to the conventional ESD group,due to ethical issue in clinical practice.AIM To determine whether and how hybrid ESD was superior to conventional ESD in the endoscopic treatment of gastric lesions in an ex vivo porcine model basic study.METHODS Sixteen endoscopists participated in this basic study in August 2020 at Kyushu University,performing 32 procedures each for hybrid ESD and conventional ESD.Mock lesions(10-15 mm,diameter)were created in the porcine stomach.The primary outcome was total procedure time and secondary outcomes were en bloc or complete resection,perforation,procedure time/speed for both,mucosal incision,and submucosal dissection.Factors associated with difficulty in ESD including longer procedure time,incomplete resection,and perforation,were also investigated.Categorical and continuous data were analyzed using the chi-square test or Fisher’s exact test and the Mann-Whitney U test,respectively.RESULTS The median total procedure time of hybrid ESD was significantly shorter than that of conventional ESD(median:8.3 min vs 16.2 min,P<0.001).Time,speed,and the amount of hyaluronic acid during submucosal dissection were more favorable in hybrid ESD than conventional ESD(time,5.2 min vs 10.4 min,P<0.001;speed,43.7 mm^(2)/min vs 23.8 mm^(2)/min,P<0.00;injection volume,1.5 mL vs 3.0 mL,P<0.001),although no significant differences in those factors were observed between both groups during mucosal incision.There was also no significant difference between both groups in the en bloc/complete resection rate and perforation rate(complete resection,93.8%vs 87.5%,P=0.67;perforation,0% vs 3.1%,P=1).Selection of conventional ESD as the treatment method was significantly associated with difficulties during ESD(odds ratio=10.2;highest among factors).CONCLUSION Hybrid ESD with SOUTEN improves the treatment outcomes of gastric lesions.It also has the potential to reduce medical costs since SOUTEN is a single multifunctional device that is inexpensive. | Mitsuru Esaki Eikichi Ihara Norikazu Hashimoto Shuichi Abe Chihoko Aratono Noriko Shiga Yorinobu Sumida Hiroyuki Fujii Kazuhiro Haraguchi Shunsuke Takahashi Tsutomu Iwasa Kayoko Nakano Masafumi Wada Shinichi Somada Kei Nishioka Yosuke Minoda Haruei Ogino Yoshihiro Ogawa | 2021 | World Journal of Gastrointestinal Surgery2021，13，6： | 0 |
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