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| 1 | Unexpected alliance between syndecan-1 and innatelike T cells to protect host from autoimmune effects of interleukin-17显示文摘Innate-like T cells, namely natural killer T(NKT) and γδ T cells, play critical roles in linking innate and adaptive immune responses through rapid production of cytokines. Prominent among these cytokines is interleukin-17(IL-17), which is a potent proinflammatory cytokine that plays a critical role in host defense against fungi and extracellular bacteria. However, excessive IL-17-production promotes autoimmune diseases, including psoriasis, multiple sclerosis, rheumatoid arthritis, inflammatory bowel disease, and systemic lupus erythematosus. IL-17 has also been implicated in regulating body fat, which is highly relevant given rises in obesity and type 2 diabetes. NKT cells, γδ T cells and mucosal-associated invariant T cells(MAIT) are the major sources of IL-17 involved in protection of mucosal surfaces from opportunistic infections and causing autoimmunity when become dysregulated. Given the pathogenic effects of IL-17, efforts have been directed towards understanding mechanisms that guard against IL-17 overproduction. One novel potent mechanism is mediated by the heparan sulfate proteoglycan, syndecan-1(sdc1), which is selectively expressed by IL-17-producing subsets of NKT and γδ T cells. This unexpected role for sdc1 is uncovered by analysis of NKT and γδ T cells in sdc1-deficient mice. In this mini-review, we discuss selective expression of sdc1 by these innate T cells and consequences of its absence on IL-17 homeostasis and pathological implications. | Anil Kumar Jaiswal Mohanraj Sadasivam Abdel Rahim A Hamad | 2018 | World Journal of Diabetes2018，9，12： | 5 |
| 2 | Anaesthesia and epileps显示文摘 | Perks A Cheema S Mohanraj R | | 0，，04： | 1 |
| 3 | High levels of fusidic acid-resistant Staphylococcus aureus despite restrictions on antibiotic use显示文摘 | Mitra A Mohanraj M Shah M | 2009 | Clin Exp Dennatol2009，34，2： | 1 |
| 4 | Heavy metal in airborne particulate matter of urban Coimbatore 显示文摘 | Mohanraj R Azeez P A Priscilla T | 2004 | Archives of Environmental Contamination and Toxicology2004，47，2： | 1 |
| 5 | Orientation of polyoxymethylene by rolling with side constraints显示文摘 | Mohanraj J Morawiec J Pawlak A | 2008 | Polymer2008，49，： | 1 |
| 6 | Production and properties of highly oriented polyoxymethylene by die- drawing显示文摘 | Taraiya A K Mirza MS Mohanraj J | 2003 | Journal of Applied Polymer Science2003，88，2： | 1 |
| 7 | Production, properties and impact toughness of die-drawing toughened polypropylenes显示文摘 | Mohanraj J Chapleau N Ajji A | 2003 | Polymer Engineering and Science2003，43，6： | 1 |
| 8 | Heavy metals in airborne particulate matter of urban Coimbatore显示文摘 | Mohanraj R Azeez P A Priscilla T | 2004 | Archires of Environmental Contamination and Toxicology2004，47，2： | 1 |
| 9 | Heavy metals in airborne particulate matter of urban Coimbatore 显示文摘 | MOHANRAJ R AZEEZ P A PRISCILLA T | 2004 | Archives of Environmental Contamination and Toxicology2004，47，2： | 1 |
| 10 | Vacular permeaility f actor gene expession in normal and neoplastic human ovaries显示文摘 | Mohanraj D Linda F | 1994 | Cancer Res1994，54，： | 1 |
| 11 | Production and properties of highly oriented polyoxymethylene by die-drawing 显示文摘 | Taraiya A K Mirza M S Mohanraj J | 2003 | Journal of Applied Polymer Science2003，88，2： | 1 |
| 12 | Production, properties and impact toughness of die-drawn toughened polypropylenes 显示文摘 | Mohanraj J Chapleau N Ajji A | 2003 | Polymer Engineering and Science2003，43，6： | 1 |
| 13 | Production,properties and impact toughness o显示文摘 | Mohanraj J Chapleau N Ajji A | 2003 | Polym Eng Sci2003，43，： | 1 |
| 14 | Orienta- tion of polyoxymethylene by rolling with side con- straints 显示文摘 | Mohanraj J Morawiec J Pawlak A | 2008 | Polymer2008，49，： | 1 |
| 15 | Synthesis and photoluminescence properties of novel lanthanide comple- xes based on pyrazolone Schiff bases显示文摘 | Listkowski A Osinska W Mohanraj J | 2012 | Syn Met2012，162，1314： | 1 |
| 16 | Production and properties of highly oriented polyoxymethylene by die-drawing显示文摘 | Taraiya A Mirza M Mohanraj J | 2003 | Journal of Applied Polymer Science2003，88，5： | 1 |
| 17 | Pollution status of wetlands in urban Coimbatore, Tamilnadu, India显示文摘 | Mohanraj R Sathishkumar M Azeez P A | 2000 | Bulletin of Environmental Contamination and Toxicology2000，64，： | 1 |
| 18 | Anaesthesia and epilepsy显示文摘 | Perks A Cheema S Mohanraj R | | 0，，04： | 1 |
| 19 | Tumor embolism from a right atrial myxoma leads to acute right heart failure after surgery and atrial septal patch dehiscence 显示文摘 | Sivakumar K Singhi A Mohanraj A | 2014 | J Am Coil Cardiol2014，63，23： | 1 |
| 20 | Heavy metal in airborne particulate matter of urban Coimbatore显示文摘 | Mohanraj R Azeez P A Priscilla T | 2004 | Archives of Enviromental Contamination and Toxicology2004，47，2： | 1 |
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