|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Neutrophil depletion-but not prevention of Kupffer cell activation-decreases the severity of cerulein-induced acute pancreatitis显示文摘瞄准:为了决定嗜中性的弄空和 Kupffer 房间抑制是否可能联合,他们的 protective 完成尖锐胰腺炎的严厉到减少。方法:老鼠有 cerulein 管理导致尖锐胰腺炎并且是有任何一个反老鼠 neutrophil 浆液或金轧氯化物(GdCl3 ) 的 pretreated 阻止 Kupffer 房间激活,或两个处理。损害在胰和肺被估计。Myeloperoxidases (军邮局) 估计了嗜中性的渗入。Interleukin-6 (IL-6 ) 和 IL-10 在浆液,胰,肺和肝被测量。结果:在有尖锐胰腺炎的老鼠,嗜中性的弄空减少了胰腺炎和联系胰腺炎的肺损害的严厉。在由 GdCl3 的激活的 Kupffer 房间有更少的保护的效果,尽管 IL-6 和 IL-10 集中显著地被减少。嗜中性的弄空带的普雷茨氏疗法没被 Kupffer 房间在激活提高,两个处理没联合他们的保护的效果。结论:当 Kupffer 房间激活的角色是不太明显的时,我们的结果在在尖锐胰腺炎加重机关损害证实激活的 neutrophils 的角色。 | Catherine M Pastor Alain Vonlaufen Fabianna Georgi Antoine Hadengue Philippe Morel Jean-Louis Frossard | 2006 | World Journal of Gastroenterology2006，12，8： | 22 |
| 2 | Epidural anesthesia improves pancreatic perfusion and decreases the severity of acute pancreatitis显示文摘AIM: To study the safety of epidural anesthesia(EA),its effect on pancreatic perfusion and the outcome of patients with acute pancreatitis(AP).METHODS: From 2005 to August 2010,patients with predicted severe AP [Ranson score ≥ 2,C-reactive protein > 100 or necrosis on computed tomography(CT)] were prospectively randomized to either a group receiving EA or a control group treated by patientcontrolled intravenous analgesia. Pain management was evaluated in the two groups every eight hours using the visual analog pain scale(VAS). Parameters for clinical severity such as length of hospital stay,use of antibiotics,admission to the intensive care unit,radiological/clinical complications and the need for surgical necrosectomy including biochemical data were recorded. A CT scan using a perfusion protocol was performed on admission and at 72 h to evaluate pancreatic blood flow. A significant variation in blood flow was defined as a 20% difference in pancreatic perfusion between admission and 72 h and was measured in the head,body and tail of the pancreas.RESULTS: We enrolled 35 patients. Thirteen were randomized to the EA group and 22 to the control group. There were no differences in demographic characteristics between the two groups. The Balthazar radiological severity score on admission was higher in the EA group than in the control group(mean score 4.15 ± 2.54 vs 3.38 ± 1.75,respectively,P = 0.347) and the median Ranson scores were 3.4 and 2.7 respectively(P = NS). The median duration of EA was 5.7 d,and no complications of the epidural procedure were reported. An improvement in perfusion of the pancreas was observed in 13/30(43%) of measurements in the EA group vs 2/27(7%) in the control group(P = 0.0025). Necrosectomy was performed in 1/13 patients in the EA group vs 4/22 patients in the control group(P = 0.63). The VAS improved during the first ten days in the EA group compared to the control group(0.2 vs 2.33,P = 0.034 at 10 d). Length of stay and mortality were not statistically different between the 2 groups(26 d vs 30 d,P = 0.65,and 0% for both respectively).CONCLUSION: Our study demonstrates that EA increases arterial perfusion of the pancreas and improves the clinical outcome of patients with AP. | Samira M Sadowski Axel Andres Philippe Morel Eduardo Schiffer Jean-Louis Frossard Alexandra Platon Pierre-Alexandre Poletti Leo Bühler | 2015 | World Journal of Gastroenterology2015，21，43： | 21 |
| 3 | 利用RNA干扰技术抑制水稻淀粉极限糊精酶基因表达显示文摘构建了含极限糊精酶基因片段反向重复结构的RNAi载体,抑制水稻籽粒中极限糊精酶基因表达获得了极限糊精酶基因功能缺失突变体。经酶切及序列测定证实,成功地构建了胚乳特异表达启动子启动的水稻极限糊精酶基因反向重复结构RNAi载体;通过根癌农杆菌(Agrobacterium tumefaciens)介导水稻(Oryza sativa sp.japonica)转化,经PCR及Southern杂交检测,获得28个水稻转基因再生株系;以极限糊精酶抗体对转基因株系胚乳发育期籽粒蛋白质进行Western杂交,并经SDS-PAGE极限糊精酶活性检测,结果显示,该反向重复结构在胚乳发育期表达,减少了极限糊精酶的积累,获得了不同沉默效果的转基因株系。转化株系012的极限糊精酶活性只有野生型的10%,表明该载体可有效地抑制水稻胚乳中极限糊精酶的活性。 | 黄冰艳 李忠谊 吉万全 海燕 Fleming J Morell M Rahman S | 2007 | 农业生物技术学报2007，15，1： | 13 |
| 4 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet . 2013 (9867)2013，，9867： | 2 |
| 5 | Lipid peroxidation products and antioxidants in human disease显示文摘 | Romero F J Morell F B Romero M J | 1998 | Environ Health Perspect1998，106，： | 1 |
| 6 | A review of image denoising algorithms with a new one显示文摘 | Buades A Coll B Morel J M | 2005 | Multiscale Modeling and Simulation:A SIAM Interdisciplinary Journal2005，4，2： | 1 |
| 7 | A review of image denoising algorithms, with a new one 显示文摘 | BUADES A COLL B MOREL J M | 2005 | Multiscale Modeling and Simulation2005，4，2： | 1 |
| 8 | Genotoxic and reproductive effects of an industrially contaminated soil on the earthworm Eisenia fetida显示文摘 | Bonnard M Eom IC Morel JL | 2009 | Environmental and Molecular Mutagenesis2009，50，1： | 1 |
| 9 | ASIFT A new framework for fully affine invariant image comparison显示文摘 | MOREL J M YU G | 2009 | SI- AM Journal on Imaging Sciences2009，2，2： | 1 |
| 10 | A review of image denoising algorithms,with a new one显示文摘 | Buades A Coll B Morel J M | 2005 | Multiscale Model Simul2005，4，2： | 1 |
| 11 | Influence of sludge-amendant or nutrient addition on the biodegradation of the herbicide isoproturon in soil显示文摘 | Perrin-Ganier C Schiavon F Morel J L Schiavon M | 2001 | Chemosphere2001，44，： | 1 |
| 12 | Singnal-unit analysis of the pallidum, thalamus and subthalamic nucleus in Parkinson patients 显示文摘 | Magnin M Morel A Jeanmonod D | 2000 | Neuroscience2000，96，3： | 1 |
| 13 | ASIFT:A New Framework for Fully Affine Invariant Image Comparison显示文摘 | Morel J M Yu G | 2009 | SIAM Journal on Imaging Sciences2009，2，2： | 1 |
| 14 | Early rheumatoid arthritis:A review of MRI and sonographic findings显示文摘 | Boutry N Morel M Flipo RM | | 0，，06： | 1 |
| 15 | Image selective smoothing and edge detection by nonlinear diffusion 显示文摘 | Catte F Lions P L Morel J M | 1992 | SIAM Journal on Nu- merical Analysis1992，29，1： | 1 |
| 16 | GPS Esti- mates of Ocean Tide Loading in NW-France: Deter- mination of Ocean Tide Loading Constituents and Comparison with Recent Ocean Tide Model 显示文摘 | Vergnolle M Bouin M N Morel L | 2008 | Geopgys J Int2008，173，2： | 1 |
| 17 | A non-local algorithm for im- age denoising显示文摘 | Buades A Colt B Morel J M | 2005 | IEEE Computer Vision and Pattern Rec- ognition2005，2，： | 1 |
| 18 | Effects of ultrasonic vibration on the micro-molding processing of polylactide显示文摘 | SACRISTAN M PLANTA X MORELL | 2014 | Ultrasonics Sonochemistry2014，21，1： | 1 |
| 19 | Renal synthesis of leukaemia inhibitou, factor (LIF), under normal and inflammatory conditions显示文摘 | Morel DS Taupin JL Potier M | 2000 | Cytokine2000，12，3： | 1 |
| 20 | Neighborhood Filters and PDE's显示文摘 | Buades A Coll B Morel J M | 2006 | Numerische Mathematik2006，105，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员