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| 1 | 与 transarterial chemoembolization 对待的 Hepatocellular 癌: 有参量的提高对比的 ultrasonography 的评估显示文摘 AIM:To evaluate the response of hepatocellular carcinoma(HCC) to transarterial chemoembolization(TACE) using a simplified protocol of parametric contrastenhanced ultrasound(pCEUS).METHODS:Eighteen patients with HCC(18 target tumors,diameter:2.8-12 cm) were evaluated before,and 20 d after TACE.The distribution and morphology of TACE-induced necrosis in these tumors precluded accurate evaluation by visual assessment or by simple measurements.For pCEUS,a 4.8 mL bolus of SonoVue(Bracco,Milan,Italy) was intravenously administered and analysis of tumor perfusion during the initial phase of enhancement(0-30 s post injection) was performed with dedicated software(Qontrast,Bracco,Milan,Italy).Time-intensity curves were plotted and three parameters were calculated:peak intensity(PI,in percentage %),time to peak(TTP in seconds,s) and area under the curve during wash-in(AUC-WI,in arbitrary units,a.u).Magnetic resonance imaging was the standard imaging modality for post-treatment evaluation.Changes in tumor size were recorded and response was assessed according to response evaluation criteria in solid tumors criteria.RESULTS:A statistically significant decrease in PI and AUC-WI was observed in the treated tumors post TACE;PIpre:21.5% ± 8.7%(mean ± SD),PIpost:12.7% ± 6.7%,P < 0.001,AUC-WI pre:17493 ± 9563 a.u,AUCWI post:9585 ± 5494 a.u,P < 0.001.A slight increase in TTP was noted post TACE,but this was not statistically significant;TTP pre:13.1 ± 4.3 s,TTP post:13.6 ± 4.2 s,P = 0.058).The changes in the aforementioned parameters were not accompanied by significant tumor shrinkage.CONCLUSION:pCEUS,even when limited to the study of the arterial phase of tumoral enhancement,can detect and quantify early perfusional changes in HCC post TACE. | Hippocrates Moschouris Katerina Malagari Athanasios Marinis Ioannis Kornezos Konstantinos Stamatiou Georgios Nikas Marina Georgiou Papadaki Panagiotis Gkoutzios | 2012 | World Journal of Radiology2012,4,8: | 3 |
| 2 | Findings and limitations of focused ultrasound as a possible screening test in stable adult patients with blunt abdominal trauma: a Greek study显示文摘 | Ioannis Kornezos Achilles Chatziioannou Ioannis Kokkonouzis Panagiotis Nebotakis Hippocrates Moschouris Spiridon Yiarmenitis Dimitrios Mourikis Dimitrios Matsaidonis | 2010 | European Radiology2010,,1: | 1 |
| 3 | Chemoembolizationwith doxorubicin-eluting beads for unresectable hepatocellularcarcinoma : five-year survival analysis 显示文摘 | Malagan K Pomoni M Moschouris H | 2012 | Cardiovasc InterventRadiol2012,35,5: | 1 |
| 4 | Transcatheter arterial embolization as therapy of renal angiomyolipomas: The evolution in 15 years of experience显示文摘 | A. Chatziioannou D. Gargas K. Malagari I. Kornezos I. Ioannidis E. Primetis H. Moschouris A. Gouliamos D. Mourikis | 2011 | European Journal of Radiology2011,,9: | 1 |
| 5 | Imaging of the acute scrotum:is there a place for contrast-enhanced ultrasonography?显示文摘 | Moschouris H Stamatiou K Lampropoulou E | 2009 | Int Braz J Urol2009,35,7: | 1 |
| 6 | Prospective Randomized Comparison of Chemoembolization with Doxorubicin-Eluting Beads and Bland Embolization with BeadBlock for Hepatocellular Carcinoma显示文摘 | Katerina Malagari Mary Pomoni Alexis Kelekis Anastasia Pomoni Spyros Dourakis Themis Spyridopoulos Hippokratis Moschouris Emmanouil Emmanouil Spyros Rizos Dimitrios Kelekis | 2010 | CardioVascular and Interventional Radiology2010,,3: | 1 |
| 7 | Imaging of the acute scrotum:is there a place for contrast-enhanced ultrasonography显示文摘 | Moschouris H Stamatiou K Lampropoulou E | | 0,,06: | 1 |
| 8 | Imaging of the acute scrotum:Is there a place for contrast-enhanced ultrasonography显示文摘 | Moschouris H Stamatiou K Lampropoulou E | | 0,,06: | 1 |
| 9 | A prospective interventional study in? chronic prostatitis? with emphasis to clinical fea-tures显示文摘 | Stamatiou KN Moschouris H | 2014 | Urol J2014,11,4: | 1 |
| 10 | Unenhanced and contrast-enhanced ultrasonography during hepatic transarterial embolization and chemoembolization with drug-eluting beads显示文摘 | Moschouris H Malagari K Kornezos I | 2010 | Cardiovasc Intervent Radiol2010,33,6: | 1 |
| 11 | Prospective Randomized Comparison of Chemoembolization with Doxorubicin-Eluting Beads and Bland Embolization with BeadBlock for Hepatocellular Carcinoma显示文摘 | Katerina Malagari Mary Pomoni Alexis Kelekis Anastasia Pomoni Spyros Dourakis Themis Spyridopoulos Hippokratis Moschouris Emmanouil Emmanouil Spyros Rizos Dimitrios Kelekis | 2010 | CardioVascular and Interventional Radiology2010,,3: | 1 |
| 12 | Chemoembolization of Hepatocellular Carcinoma with Hepasphere 30–60 μm. Safety and Efficacy Study显示文摘 | Katerina Malagari Maria Pomoni Hippokratis Moschouris Alexios Kelekis Angelos Charokopakis Evanthia Bouma Themistoklis Spyridopoulos Achilles Chatziioannou Vlasios Sotirchos Theodoros Karampelas Constantin Tamvakopoulos Dimitrios Filippiadis Enangelos Kar | 2014 | CardioVascular and Interventional Radiology2014,,1: | 1 |
| 13 | Imaging of the acute scrotum:is there a place for contrast-enhanced ultrasonography显示文摘 | Moschouris H Stamatiou K Lampropoulou E | | 0,,6: | 1 |
| 14 | Sonographic evaluation of prostatic artery embolization:Far beyond size measurements显示文摘Prostatic artery embolization(PAE)has gained acceptance as a minimally invasive,safe and effective treatment of symptomatic benign prostatic hyperplasia.Radiologic imaging is an indispensable part of post-interventional evaluation of PAE and serves both clinical and investigational purposes.In this context,ultrasonography(US)has a central and multifaceted role.Gray-scale US is routinely utilized for measurement of significant outcome parameters(prostatic volume,intra-vesical prostatic protrusion and post-void residual volume)before and after PAE.Improvement of these parameters may become more obvious onemonth post-PAE,or later.Contrast-enhanced US(CEUS)with intravenous administration of a second-generation echo-enhancer can demonstrate prostatic infarcts(as enhancement defects)immediately post-PAE and monitor their resolution over time.The volume of prostatic infarcts can also be measured and compared to prostatic volume.Prostatic infarction is a definite sign of the local efficacy of PAE and a predictor of prostate shrinkage and(at least in some patients)of clinical success.CEUS can also be performed intraoperatively in the angio-suite,for on-site evaluation of the ischemic effect;a variation of this technique,with intraarterial(instead of intravenous)administration of diluted echo enhancer,can also be applied intraoperatively,to map the embolized territory and to prevent non-target embolization.Initial experience with USelastographic techniques(shear-wave and strain elastography)has shown that they can detect and quantify the improvement of tissue elasticity post-PAE,thus providing new insights into the therapeutic mechanisms of this treatment.With utilization of high-end equipment,experience and standardized imaging protocols,US could be the primary modality for imaging evaluation of PAE. | Hippocrates Moschouris Andreas Dimakis Anastasia Anagnostopoulou Konstantinos Stamatiou Katerina Malagari | 2020 | World Journal of Radiology2020,12,8: | 0 |