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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Nitrobenzene removal in bioelectrochemical systems 显示文摘 | Mu Y Rozendal R A Rabaey K | 2009 | Environmental Science and Technology2009，43，22： | 1 |
| 3 | Lipid-based formulations for oral administration of poorly water-soluble drugs 显示文摘 | Mu H Holm R Mtillertz A | 2013 | Int J Pharm2013，453，1： | 1 |
| 4 | Regional evaporation estimates from flux tower and MODIS satellite data显示文摘 | Cleugh H A Leuning R Mu Q Z | 2007 | Remote Sensing of Environment2007，106，： | 1 |
| 5 | Prognostic value of HIV-1 RNA,CD4 cell count,and CD4 Cell count slope for progression to AIDS and death in untreated HIV-1infection显示文摘 | Mellors J W Margolick J B Phair J P Rinaldo C R Detels R Jacobson L P Mu noz A | 2007 | JAMA2007，297，21： | 1 |
| 6 | Recent advances in two-phase partitioning bioreactors for the treatment of volatile organic compounds显示文摘 | Mu(n)oz R Daugulis A J Hernández M | 2012 | Biotechnol Adv2012，30，6： | 1 |
| 7 | Existence and uniqueness of solutions for multi-point boundary value problems for fractional differential equations显示文摘 | REHMAN MU KHAN R A | 2010 | Applied Mathematics Letters2010，23，： | 1 |
| 8 | Lipid-based formulations for oral administration of poorly water-soluble drugs 显示文摘 | Mu H Holm R Miillertz A | 2013 | Int J Pharm2013，453，： | 1 |
| 9 | Optical and structural cha- racterization of copper indium disulfide thin films显示文摘 | Henderson D O Mu R Ueda A | 2001 | Mater Design2001，22，7： | 1 |
| 10 | On-line dead-time compen- sation technique for open-loop PWM-VSI drives显示文摘 | ALFREDO R MU THOMAS A LIPO | 1999 | IEEE Trans- actions on Power Electronics1999，14，4： | 1 |
| 11 | Mismatch repair gene mutations in Chinese HNPCC patients显示文摘 | Sheng J Q Fu L Sun Z Q Huang J S Han M Mu H Zhang H Zhang Y Z Zhang M Z Li A Q Wu Z T Han Y Li S R | 2008 | Cytogenetic and Genome Research2008，，1： | 1 |
| 12 | Genome sequence and analysis of the tuber crop potato显示文摘 | Xu X Pan S Cheng S Zhang B Mu D Ni P Zhang G Yang S Li R Wang J Orjeda G Guzman F Tones M Lnzano R Ponce O Martinez D De la Cruz G Chakrabarti S K Patil V U Skryabin K G Kuznetsov B B Ravin N V Kolganova T V Beletsky A V Mardanov A V Di Genova A Bolser D M Martin D M Li G Yang Y Kuang H Hu Q Xiong X Bishop G J Sagredo B Mejia N Zagorski W Gromadka R Gawor J Szczesny P Huang S Zhang Z Liang C He J Li Y He Y Xu J Zhang Y Xie B Du Y Qu D Bonierbale M Ghislain M Herrera Mdel R Giuliano G Pietrella M Perrotta G Faeella P O 'Brien K Feingold S E Barreiro L E Massa G A Diambra L Whitty B R Vaillancourt B Lin H Massa A N Geoffroy M Lundback S DellaPenna D Buell C R Sharma S K Marshall D F Waugh R Bryan G J Destefanis M Nagy I Milbourne D Thomson S J Fiefs M Jacobs J M Nielsen K L Sonderkaer M Iovene M Tortes G A Jiang J Veilleux R E Bachem C W de Boer J Bonn T Kloosterman B van Eck H Datema E Hekkert B Goverse A van Ham R C Visser R G | 2011 | Nature2011，475，7355： | 1 |
| 13 | Mice lacking endogenous IL-10-producing regulatory B cells develop exacerbated disease and present with an increased frequency of Th1/Th17 but a decrease in regulatory T cells显示文摘 | Carter NA Vasconcellos R Rosser EC Tulone C Muoz-Suano A Kamanaka M Ehrenstein MR Flavell RA Mauri C | | 0，，10： | 1 |
| 14 | Sensing of liquid level at micron resolution using self-exited milli meter sized PZT-cantilever显示文摘 | CAMPBELL G A MU THARASAN R | 2005 | Sensors and A actua tors A2005，122，： | 1 |
| 15 | Hexavalent chromi- um removal from aqueous medium by active carbon pre- pared from peanut shell: Adsorption kinetics, equilibrium and thermodynamic studies 显示文摘 | Z A Al-Othman R Ali Mu Naushad | 2012 | Chemical Engineerin Jour- nal2012，，184： | 1 |
| 16 | Evidences for pore mouth and key-lock catalysis in hydroisomerization of long n-alkanes over 10-ring tubular pore bifunctional zeolites显示文摘 | MARTENS J A VANBUTSELE G JACOBS P A DENAYER J OCAKOGLU R BARON G MUИOZ-ARROYO J A THYBAUT J MARIN G B | 2001 | Catal Today2001，65，24： | 1 |
| 17 | Seed growth suppression constrains the growth of seed parasites:premature acorn abscission reduces Curculio elephas larval size显示文摘 | Bonal R Muoz A | | 0，，： | 1 |
| 18 | Decolorization of azo dyes in bioelectrochemical systems 显示文摘 | Mu Yang Rabaey K Rozendal R A | 2009 | Environmental Science & Technology2009，43，13： | 1 |
| 19 | Spanish-Latin American Multicenter Study of Attitudes Toward Organ Donation Among Personnel From Hospital Healthcare Centers显示文摘 | Antonio Ríos Ana López-Navas Marco Antonio Ayala-García María José Sebastián Anselmo Abdo-Cuza Jeannina Alán Laura Martínez-Alarcón Ector Jaime Ramírez Gerardo Mu?oz Juliette Suárez-López Roberto Castellanos Ricardo Ramírez Beatriz González Miguel Angel M | 2013 | Cirugía Espa?ola (English Edition)2013，，： | 1 |
| 20 | Deeolorization of azo dyes in bioeleetmchemical systems显示文摘 | Mu Y Rabaey K Rozendal R A | 2009 | Environmental Scienee & Teehnolo- gy2009，43，： | 1 |
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