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| 1 | 根据血压等级确定脑卒中和冠状动脉粥样硬化性心脏病死亡的终生风险:日本EPOCH(观察队列的心血管预防证据)研究显示文摘在亚洲人群中.很少研究关注根据血压分类确定脑卒中和冠状动脉粥样硬化性心脏病(coronary heartdisease,CHD)的终生风险。该研究旨在用一个包含个体参与者数据的荟萃分析大数据库来评估它。该荟萃分析纳入来源于13个队列的107 737名日本人(男性占42.4%,平均年龄55.1岁)。在平均(15.2±5.3)年(1 559 136人年)的随访期.1922人死于脑卒中,913人死于CHDO研究者在调整其他死亡危险因素后估计风险。 | 陈嘉睿(译) 练桂丽(审校) Satoh M Ohkubo T Asayama K Murakami Y Sugiyama D Yamada M Saitoh S Sakata K Irie F Sairenchi T Ishikawa S Kiyama M Ohnishi H Miura K Imai Y Ueshima H Okamura T EPOCH-JAPAN research group | 2019 | 中华高血压杂志2019，27，4： | 9 |
| 2 | Incidence and characteristics of HBV reactivation in hematological malignant patients in south Egypt显示文摘AIM:To investigate characteristics of hepatitis B virus(HBV)implicated in HBV reactivation in patients with hematological malignancies receiving immunosuppressive therapy.METHODS:Serum samples were collected from 53 patients with hematological malignancies negative for hepatitis B surface antigen(HBsAg)before the start of and throughout the chemotherapy course.HBV reactivation was diagnosed when the HBsAg status changed from negative to positive after the initiation of chemotherapy and/or when HBV DNA was detected by realtime detection polymerase chain reaction(RTD-PCR).For detecting the serological markers of HBV infection,HBsAg as well as antibodies to the core antigen(antiHBc)and to the surface antigen were measured in the sera by CEIA.Nucleic acids were extracted from sera,and HBV DNA sequences spanning the S gene were amplified by RTD-PCR.The extracted DNA was further subjected to PCR to amplify the complete genome as well as the specific genomic sequences bearing the enhancerⅡ/core promoter/pre-core/core regions(nt1628-2364).Amplicons were sequenced directly.RESULTS:Thirty-five(66%)of the 53 HBsAg-negative patients were found to be negative serologically for antiHBc,and the remaining 18(34%)patients were positive for anti-HBc.Five of the 53(9.4%)patients with hematologic malignancies experienced HBV reactivation.Genotype D1 was detected in all five patients.Four types of mutant strains were detected in the S gene product of HBV strains and were isolated from 3 patients with HBV reactivation:T/S120,L143,and I126.HBV DNA was detected in the pretreatment HBsAg-negative samples in one of the five patients with HBV reactivation.In this patient,sequences encompassing the HBV full genome obtained from sera before the start of chemotherapy and at the time of de novo HBV hepatitis were detected and it showed 100%homology.Furthermore,in the phylogenetic tree,the sequences were clustered together,thereby indicating that this patient developed reactivation from an occult HBV infection.CONCLUSION:Past infection with HBV is a risk factor for HBV reactivation in Egypt.Mandatory anti-HBc screening prior to chemotherapy in patients with hematological malignancies is recommended. | Abeer Elkady Sahar Aboulfotuh Elsayed Mostafa Ali Douaa Sayed Nashwa M Abdel-Aziz Amany M Ali Shuko Murakami Sayuki Iijima Yasuhito Tanaka | 2013 | World Journal of Gastroenterology2013，19，37： | 7 |
| 3 | Aclivation of the precursor of gelatinase A/72 KD type Ⅳ colleguenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase and with lymph node metastasis显示文摘 | Tokurku M Sato H Murakami S | 1995 | Int J Cancer1995，，： | 5 |
| 4 | Hypervascular hepatocellular carcinoma: detection with double arterial phase multi-detector row helical CT显示文摘 | Murakami T Kim T Takamura M | 2001 | Radiology2001，218，3： | 2 |
| 5 | Characteristics of escape mutations from occult hepatitis B virus infected patients with hematological malignancies in South Egypt显示文摘AIM To investigate the prevalence and virological characteristics of occult hepatitis B virus(HBV) infections in patients with hematological malignancies in South Egypt.METHODS Serum samples were collected from 165 patients with hematological malignancies to monitor titers of HBV DNA, hepatitis B surface antigen(HBs Ag), and antibodies to HBV core(anti-HBc) and surface antigens. Serum samples negative for HBs Ag and positive for anti-HBc were subjected to nucleic acid extraction and HBV DNA detection by real-time polymerase chain reaction. DNA sequences spanning the S region were analyzed in cases with occult HBV infection. In vitro comparative study of constructed 1.24-fold wild type and S protein mutant HBV genotype D clones was further performed. RESULTS HBV DNA was detected in 23(42.6%) of 54 patients with hematological malignancies who were HBsA g negative, but anti-HBc positive, suggesting the presence of occult HBV infection. The complete HBV genome was retrieved from 6 occult HBV patients, and P120 T and S143 L were detected in 3 and 2 cases, respectively. Site directed mutagenesis was done to produce 1.24-fold genotype D clones with amino acid mutations T120 and L143. The in vitro analyses revealed that a lower level of extracellular HBsA g was detected by chemiluminescence enzyme immunoassay(CLEIA) with the clone containing T120 mutation, compared with the wild type or the clone with S143 L mutation despite the similar levels of extracellular and intracellular HBs Ag detected by Western blot. Southern blot experiments showed that the levels of intracellular HBV DNA were not different between these clones. CONCLUSION Occult HBV infection is common in patients with hematological malignancies and associated with P120 T and S143 L mutations. 120 T mutation impairs the detection of HBsA g by CLEIA. | Abeer Elkady Sayuki Iijima Sahar Aboulfotuh Elsayed Mostafa Ali Douaa Sayed Nashwa M Abdel-Aziz Amany M Ali Shuko Murakami Masanori Isogawa Yasuhito Tanaka | 2017 | World Journal of Hepatology2017，9，9： | 2 |
| 6 | Drug combinations with amoxycillin reduce selection of clarithromycin resistance during Helicobacter pylori eradication therapy显示文摘 | K Murakami T Fujioka T Okimoto R Sato M Kodama M Nasu | 2002 | International Journal of Antimicrobial Agents2002，，1： | 2 |
| 7 | Treatment of bronchial stricture due to endobronchial tuberculosis显示文摘 | Watanabe Y Murakami S Oda M | 1997 | World J Surg1997，21，5： | 2 |
| 8 | Stroke rehabilitation outcome study:a comparison of Japan with the United States显示文摘 | Murakami M Inouye M | 2002 | Am J Phys Med Rehabil2002，81，4： | 2 |
| 9 | Phospholipase A2 显示文摘 | Murakami M Kudol I | 2002 | Biochem2002，131，： | 2 |
| 10 | Role of adiponectin in insulin-resistant hypertension and atherosclerosis显示文摘 | Murakami H Ura N Furuhashi M Higashiura K | 2003 | Hypertens Res2003，26，9： | 2 |
| 11 | First principles calculation of stable structure and adhesive strength of plated Ni/Fe(100) or Cu/Fe(100) interfaces显示文摘A study the with first principles calculation of the interfaces of the Ni layer or Cu layer on the Fe(100) surface formed with metal plating was performed.Ni or Cu atoms were shown to adopt the corresponding position to the bcc structure of the Fe(100) substrate.Other calculations showed that the interfaces of Ni(5 atomic layers)/Fe(100)(5 layers) or Cu(5 atomic layers)/Fe(100)(5 layers) had square lattices.The orientation relationship of Ni/Fe(100) interface corresponds to fcc-Ni(100)//bcc-Fe(100),Ni[011]//Fe[010],and Ni[011]//Fe[001].Similar results were obtained for Cu/Fe(100) interfaces.This structure was supported by TEM analysis of plated Ni layer on Fe(100) surfaces.The adhesion strength of the Ni/Fe(100) interface evaluated by first principles calculation was higher than that of the Cu/Fe(100) interface.The experimental results of Hull cell iron plated with Ni or Cu supported the results of the calculation.These results indicate that the first principles calculation,which deals with the ideal interface at the atomic scale,has the potential to evaluate the adhesion strength of metallic material interfaces. | Ryota NAKANISHI Koji SUEOKA Seiji SHIBA M akoto HINO Koji MURAKAMI Ken MURAOKA | 2009 | 中国有色金属学会会刊:英文版2009，19，4： | 2 |
| 12 | Thymic hyperplasia inpatientswith Graves disease:Identification of thyrotropin receptors in human thymus显示文摘 | Murakami M Hosoi Y Negishi T | 1996 | J Clin Invest1996，98，10： | 1 |
| 13 | Anti-red blood cell autoantibody transgenic mice: murine model of autoimmune hemolytic anemia显示文摘 | Murakami M Honjo T | 1996 | Semin Immunol1996，8，： | 1 |
| 14 | Small hypervascular hepatocellular carcinoma revealed by double arterial phase CT per formed with single breath-hold scanning and automatic bolus tracking 显示文摘 | Kim T Murakami T Hori M etal | 2002 | AJR Am J Roentgenol2002，178，4： | 1 |
| 15 | Dexamethasone regulates obese expression in isolated rat adipocytes显示文摘 | Iida M Shima K | 1995 | Biochem Biophys Res Comm1995，214，3： | 1 |
| 16 | Cardiac troponin Ⅰ and T alterations in dog hearts with myocardial infarction:correlation with infarct size显示文摘 | Sharkey S W Murakami M M | 1998 | Am J Clin Pathol1998，110，： | 1 |
| 17 | Identification of monoclonal insulin autoantibodies in insulin autoimmune syndrome associated with HLA - DRB1 * 0401 显示文摘 | Mizuide M Kashima K | 2000 | Horm Res2000，54，1： | 1 |
| 18 | Juvenile amyotrophy of the distal upper extremity:pathologic findings of the dura mater and surgical management显示文摘 | Konno S Goto S Murakami M etal | 1997 | Spine1997，22，5： | 1 |
| 19 | Structural basis for tropomyosin overlap in thin(actin)filaments and the generation of a molecular swivel by troponin-T显示文摘 | Murakami K Stewart M Nozawa K | 2008 | Proc Natl Acad Sci USA2008，105，20： | 1 |
| 20 | New flavonol oligoglycosides and polyacylated sucroses with inhibitory effects on aldose reductase and platelet aggregation from the flowers of Prunus mume显示文摘 | Yoshikawa M Murakami T Ishiwada T | 2002 | Journal of Natural Products2002，65，8： | 1 |
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