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| 1 | 前房注射头孢呋辛对术后眼内炎的预防作用(英文)显示文摘目的:研究前房注射头孢呋辛对术后眼内炎的预防作用。方法:回顾性研究6 099例行超声乳化白内障手术的年龄相关性白内障患者。对照组,2001-10/2004-05,3 075例3 075眼行白内障手术未用眼内抗生素,实验组,2004-06/2007-04,3 024例3 024眼术中前房用0.1mL含1mg的头孢呋辛。两组的术前预防措施和手术步骤相同。结果:对照组和实验组分别有13(0.42%)和4(0.13%)例患者发生术后眼内炎[P=0.031;OR =3.20(1.04-9.84)]。两组发生术后眼内炎的平均时间分别是术后30(3 ~75)d和25(2 ~35)d(P=0.35)。研究细菌感染,实验组,烟曲菌和铜绿假单胞菌对头孢呋辛耐药,而肺炎链球菌对头孢呋辛敏感。未发现前房运用头孢呋辛的毒性和过敏性症状。结论:预防性前房运用头孢呋辛是安全的,可以预防术后细菌性眼内炎。然而抗生素抗菌谱窄和抗生素耐药性的可能性需要考虑。 | Güngr Sobaci Yusuf Uysal Fatih M Mutlu Atilla Bayer Rιza Gungor Suat Karagul | 2009 | 国际眼科杂志2009，9，8： | 2 |
| 2 | Mechanisms of pulmonary edema clearance显示文摘 | Mutlu G M Sznajder J I | 2005 | Am J Physiol Lung Cell Mol Physiol2005，289，5： | 1 |
| 3 | p53 mediates particulate matter-induced alveolar epithelial cell mitochondria regulated apoptosis显示文摘 | Soberanes S Panduri V Mutlu G M | 2006 | Am J Respir Crit Care Med2006，174，11： | 1 |
| 4 | Effects of moxifloxacin exposure on the conjunctival flora and antibiotic resistance profile following repeated intravitreal injections显示文摘AIM:To evaluate the effects of moxifloxacin exposure on the conjunctival flora and antibiotic resistance profile following repeated intravitreal injections.METHODS:Seventy-two eyes of 36 patients [36 eyes in control group, 36 eyes in intravitreal injection(IVI) group]were enrolled in the study. All the eyes had at least one IVI and had diabetic macular edema(DME) or age-related macular degeneration(ARMD). Moxifloxacin was prescribed to all the patients four times a day for five days following injection. Conjunctival cultures were obtained from the lower fornix via standardized technique with every possible effort made to minimize contamination from the lids, lashes, or skin. Before the application of any ophthalmic medication, conjunctival cultures were obtained from both eyes using sterile cotton culture. An automated microbiology system was used to identify the growing bacteria and determine antibiotic sensitivity.RESULTS:The bacterial cultures were isolated from 72 eyes of 36 patients, sixteen of whom patients(44.4%)were male and twenty(55.6%) were female. Average age was 68.4 ±9.0(range 50-86). The average number of injections before taking cultures was 3.1+1.0. Forty-eight(66.7%) of 72 eyes had at least one significant organism.There was no bacterial growth in 8(20.5%) of IVI eyes and in 16(44.4%) of control eyes(P =0.03). Of the bacteria isolated from culture, 53.8% of coagulase negative staphylococci(CoNS) in IVI eyes and 47.2%CoNS in control eyes. This difference between IVI eyes and control eyes about bacteria isolated from culture was not statistically significant(P =0.2). Eleven of 25 bacteria(44.0%) isolated from IVI eyes and 11(57.9%) of 19 bacteria isolated from control eyes were resistant to oxacillin. The difference in frequency of moxifloxacine resistance between two groups was not statistically significant(12.0% in IVI eyes and 21.1% in control eyes)(P =0.44). There were no cases of resistance to vancomycin, teicoplanin and linezolid.CONCLUSION:There was no difference in species of bacteria isolated from cultures, or in the frequency of resistance to antibiotics between eyes that had recurrent IVI followed by moxifloxacin exposure compared with control eyes. However, the number of eyes that had bacterial growth was higher in IVI group than in the control group. | Mustafa Atas Burhan Baskan Ayse zkse Fatma Mutlu Sarιgüzel Süleyman Demircan Emine Pangal | 2014 | International Journal of Ophthalmology(English edition)2014，7，5： | 1 |
| 5 | Hyperbaric oxygen therapy for mitomycin C-induced scleral necrosis 显示文摘 | Bayer A Mutlu FM Sobaci G | 2002 | Ophthalmic Surg Lasers2002，33，1： | 1 |
| 6 | A comparative study of recurrent pterygium surgery; limbal conjunctival auto- graft transplantation versus mitomycin C with conjuneti val flap显示文摘 | Mutlu FM Sobaci G Tatar T | 1999 | Ophthalmology1999，106，： | 1 |
| 7 | Effects of fluoxetine,tianeptine and olanzapine on unpredictable chronic mild stress-induced depression-like behavior in mice显示文摘 | Mutlu O Gumuslu E Ulak G | 2012 | Life Sci2012，91，2526： | 1 |
| 8 | Value of diffusion- weighted MRI in the differentiation of benign and malign 5reast lesions显示文摘 | Sonmez G Cuce F Mutlu H | 2011 | Radiology2011，123，21： | 1 |
| 9 | Morphologic changes and lipid peroxidation in renal tissues of young rats following intestinal is- chemia-reperfusion显示文摘 | Mutlu G Abbasoh L Dom-Abbasolu S | 2002 | Pediar Surg Int2002，18，56： | 1 |
| 10 | Prevention of marine environment pol- lution at the tourism regions by the application of a simple method for the domestic wastewater 显示文摘 | KOCASOY G MUTLU H I | 2008 | Desalination2008，226，： | 1 |
| 11 | Effects of neuronal and induc-ible NOS inhibitor 1-(2-(trifluoromethyl)phenyl)imidazole(TRIM)in unpredictable chronic mild stress procedure in mice显示文摘 | Mutlu O Ulak G Laugeray A | 2009 | Pharmacology Biochemistry and Behavior2009，92，1： | 1 |
| 12 | Value of diffusion-weighted MRI in the differentiation of benign and malign breast lesions显示文摘 | Sonmez G Cuce F Mutlu H | 2011 | Wien Klin Wochenschr2011，123，2122： | 1 |
| 13 | Gold- ie' -supplemented modules 显示文摘 | BIRKENMEIER G F MUTLU T F NEBIYEV C | 2010 | Glasgow J Math2010，52，： | 1 |
| 14 | A comparative study of recurrent pterygium surgery: limbal conjunctival autograft transplantation versus mitomycin C with conjunctival flap显示文摘 | Mutlu FM Sobaci G Tatar T | 1999 | Ophthalmology1999，106，4： | 1 |
| 15 | Ocular Trauma Score in childhood open-globe injuries显示文摘 | Uysal Y Mutlu FM Sobaci G | 2008 | J Trauma2008，65，6： | 1 |
| 16 | Deadly weapon-related open-globe injuries:outcome assessment by the ocular trauma classification system显示文摘 | Sobaci G Mutlu FM Bayer A | 2000 | Am J Ophthalmol2000，129，1： | 1 |
| 17 | Comparison of tilt and decentration of 1-piece and 3-piece hydrophobic acrylic intt'aocular lenses 显示文摘 | Mutlu FM Erdunnan C Sobaci G | 2005 | J Cataract Refract Surg2005，31，2： | 1 |
| 18 | A comparative kinetic study of acidic hemieellulose hydrolysis in corn cob and sun- flower seed hull 显示文摘 | EKEN-SARACOGLU N MUTLU S F DILMAC G | 1998 | Bioresource Technology1998，65，12： | 1 |
| 19 | Evaluation of vitamin D supplementation doses during pregnancy in a population at high risk for deficiency显示文摘 | Yesiltepe Mutlu G Ozsu E Kalaca S | 2014 | Horm Res Paediatr2014，81，6： | 1 |
| 20 | Effects of fluoxetine,tianeptine and olanzapine on unpredictable chronic mild stress-induced depression-like behavior in mice显示文摘 | Mutlu O Gumuslu E Ulak G | 2012 | Life Sci2012，91，2526： | 1 |
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