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| 1 | Anticancer activity of Mahonia leschenaultii methanolic root extract and berberine on Dalton’s ascitic lymphoma in mice显示文摘Objective: To evaluate the effects of methanol root extract of Mahonia leschenaultii and berberine of Mahonia leschenaultii on Dalton’s ascitic lymphoma in Swiss Albino mice. Methods: The methanol root extracts of Mahonia leschenaultii(200 and 400 mg/kg) were given orally, and berberines(10 and 20 mg/kg) were injected intra-peritoneally for 14 successive days in tumor bearing mice. Hematological parameters(white and red blood cells, haemoglobin level, granulocytes, and agranulocytes), lipid parameters(total cholesterol and triglycerides), serum enzymes(serum glutamate pyruvate transaminases, serum glutamate oxaloacetate transaminases, and alkaline phosphatise) and mean survival and solid tumor growth were determined and compared with untreated mice. 5-fluorouracil(20 mg/kg) was used as a reference standard drug. Results: Mahonia leschenaultii and berberine reduced the hematocrit significantly. Furthermore, Mahonia leschenaultii and berberine improved the survival of mice significantly and restored the affected hematological and lipid parameters similar to the normal levels. Conclusions: These observations show a strong anticancer effect of methanol root extract of Mahonia leschenaultii and berberine in suppressing Dalton’s ascitic lymphoma cancer cell growth in a mouse model by controlling haematological, lipid, serum enzymes, and other derived parameters effectively. | R Latha TM Chozhavel Rajanathan Ameer Khusro N Chidambaranathan Paul Agastian Sankaranarayanan Nagarajan | 2019 | Asian Pacific Journal of Tropical Medicine2019，12，6： | 1 |
| 2 | Per- sistent trigeminal artery: A rare cause o{ trigeminal neuralgia - MR imaging 显示文摘 | Chidambaranathan N Ahmed-Sayeed Z Sunder K | 2006 | Neuroimage2006，54，2： | 1 |
| 3 | Value of dynamic MRI imaging in pituitary adenomas显示文摘 | Indrajit IK Chidambaranathan N Sundar K | 2001 | Neuroradiology2001，11，4： | 1 |
| 4 | Value of dynamic MRI imaging in pituitary adenomas显示文摘 | Indrajit IK Chidambaranathan N Sundar K | 2001 | Neuroradiology2001，11，： | 1 |
| 5 | Value of dy namic MRI imaging in pituitary adenomas显示文摘 | Indrajit IK Chidambaranathan N Sundar K | 2001 | Neuroradiol2001，11，1： | 1 |
| 6 | Persistent tri- geminal artery: a rare cause of trigeminal neuralgia-MR imaging 显示文摘 | Chidambaranathan N Sayeed ZA Sunder K | 2006 | Neurol India2006，54，2： | 1 |
| 7 | Persistent trigeminal artery:A rare cause of trigeminal neuralgia-MR imaging显示文摘 | Chidambaranathan N Ahmed-Sayeed Z Sunder K | 2006 | Neuroimage2006，54，： | 1 |
| 8 | Persistent trigeminal artery:a rare cause of trigeminal neuralgia-MR imaging显示文摘 | Chidambaranathan N Sayeed Z A Sunder K | | 0，，02： | 1 |
| 9 | Persistent trigeminal artery: A rare cause of trigeminaI neuralgia MR imaging显示文摘 | Chidambaranathan N Sayeed ZA Sunder K | 2006 | Neuroimage2006，54，2： | 1 |
| 10 | Persiatent trigeminal artery:a rare cause of trigeminal neuralgiaMR imaging显示文摘 | Chidambaranathan N Sayeed ZA Sunder K | 2006 | Neurology India2006，54，2： | 1 |
| 11 | Persistent trigeminal artery: A rare cause of trigeminal neuralgia - MR imaging显示文摘 | Chidambaranathan N Sayeed ZA Sunder K | 2006 | Neurology India2006，54，2： | 1 |
| 12 | Antitumor activity of Vitex negundo Linn against daltons ascitic lymphoma 显示文摘 | Dewade D R Christinal A J M Chidambaranathan N | 2010 | Int J Pharm Tech Res2010，2，2： | 1 |
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