|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Identification of squamous cell carcinoma associated proteins by proteomics and loss of beta tropomyosin expression in esophageal cancer显示文摘AIM: To assess the proteome of normal versus tumor tissue in squamous cell carcinoma of the esophagus (SCCE) in Iranian patients and compare our results with former reports by using proteomics. METHODS: Protein was extracted from normal and tumor tissues. Two dimensional electrophoresis was carried out and spots with differential expression were identified with mass spectrometry. RNA extraction and RT-PCR along with immunodetection were performed. RESULTS: Fourteen proteins were found whose expression levels differed in tumor compared to normal tissues. Mass spectrometric analysis resulted in the identification of β-tropomyosin (TMβ), myosin light chain 2 (and its isoform), myosin regulatory light chain 2, peroxyredoxin 2, annexinⅠand an unknown polypeptide as the down regulated polypeptides in tumor tissue. Heat shock protein 70 (HSP70), TPM4-ALK fusion oncoprotein 2, myosin light polypeptide 6, keratinⅠ, GH16431p and calreticulin were the up-regulated polypeptides found in tumor tissue. Several of these proteins, such as TMβ,HSP70, annexinⅠ, calreticulin, TPM4-ALK and isoforms of myosins, have been well recognized in tumorigenesis of esophageal or other types of cancers. CONCLUSION: Our study not only supports the involve- ment of some of the formerly reported proteins in SCCE but also introduces additional proteins found to be lost in SCCE, including TMβ. | Ferdous Rastgar Jazii Zahra Najafi Reza Malekzadeh Thomas P Conrads Abed Ali Ziaee Christian Abnet Mansour Yazdznbod Ali Asghar Karkhane Ghasem H Salekdeh | 2006 | World Journal of Gastroenterology2006，12，44： | 14 |
| 2 | Differential effects of advanced age on neuroloic and cardiac risks of coronary operations显示文摘 | Tuman KJ McCarthy RJ Najafi H | 1992 | Thorac Cardiovasc Surg1992，104，6： | 1 |
| 3 | Energy and cost opti- mization of a plate and fin heat exchanger using genetic al- gorithm 显示文摘 | Najafi H Najafi B Hoseinpoori P | 2011 | Applied Thermal Engineering2011，31，10： | 1 |
| 4 | Preparation of nanoclay-dispersed polystyrene nanofibers via atom transfer radical polymerization and electrospinning显示文摘 | Roghani-Mamaqani H Haddadi-Asl V Najafi M | 2011 | Journal of Applied Polymer Science2011，120，： | 1 |
| 5 | Heat Transfer and Pressure Drop Characteristics of Forced Convective Evaporation in Horizontal ~bes with Coiled Wire Inserts 显示文摘 | Akhavan-Behabadi M Mohseni S Najafi H | 2009 | International Communications in Heat and Mass Transfer2009，36，10： | 1 |
| 6 | A parametric frequency increased power generator for scavenging low frequency ambient vibrations显示文摘 | Galchev T Kim H Najafi K | 2009 | Procedia Chemistry2009，1，1： | 1 |
| 7 | Out- comes and quality of life in patients>85 years of age with ST-elevation myocardial infarction显示文摘 | SHAH P NAJAFI A H PANZA J A | 2009 | Am J Cardiol2009，103，： | 1 |
| 8 | Energy and cost op- timization of a plate and fin heat exchanger using genetic algo- rithm 显示文摘 | NAJAFI H NAJAFI B HOSEINPOORI P | 2011 | Applied Thermal Engineering2011，31，10： | 1 |
| 9 | The effect of adding enzyme-modified cheese on sensory and texture properties of low- and high-fat cream cheeses显示文摘 | Miri M A Najafi M B H | 2011 | International journal of dairy technology2011，64，1： | 1 |
| 10 | Expression of chemokine re- ceptors on Thl/Th2 CD4 + lymphoeytes in patients with multiple sclerosis显示文摘 | Andalib A Doulabi H Najafi M | 2011 | lran J lmrnunol2011，8，： | 1 |
| 11 | Strain hardening mechanisms in aged AEREX350 superalloy显示文摘 | H amidreza Najafi Sirous Asgari | 2005 | Materials Science and Engineering A2005，，398： | 1 |
| 12 | Microbial diversity of the traditional Iranian cheeses Lighvan andKoozeh, as revealed by polyphasic culturing and culture-independentapproaches显示文摘 | EDALATIAN M R NAJAFI M B H MORTAZAVI S A | 2012 | Dairy Science & Techonology2012，92，1： | 1 |
| 13 | As-cast mechanical properties of vanadium/niobium mieroalloyed steels 显示文摘 | Najafi H Rassizadehghani J Asgari S | 2008 | Materials Scienee and Engineering A2008，486，12： | 1 |
| 14 | Sperm status and DNA dose play key roles in sperm/ICSI-mediated gene transfer in caprine 显示文摘 | Shadanloo F Najafi M H Hosseini S M | 2010 | Mol Reprod Dev2010，77，10： | 1 |
| 15 | Differentional effects of advanced age neurologic and cardiac risks of coronary artery operation显示文摘 | Tuman KJ Me Carthy RJ Najafi H | 1992 | Thorac Cardiovasc Surg1992，104，： | 1 |
| 16 | Enhancing biosurfactant production from an indigenous strain of Bacillus mycoides by optimizing the growth conditions using a response surface methodology显示文摘 | Najafi A R Rahimpour M R Jahanmiri A H | 2010 | Chemical Engineering Journal2010，163，3： | 1 |
| 17 | Glucokinase and glucose homeostasis proven concepts and new ideas显示文摘 | Zelent D Najafi H Odili S | 2005 | Biochem Soc Tans2005，33，1： | 1 |
| 18 | A numerical comparison of two different implementations of GMRES method显示文摘 | Saberi Najafi H Zareamghaddam H | 2011 | Middle-East Journal of Scientific Research2011，8，2： | 1 |
| 19 | Comparison of the shear bond strength of orthodontic brackets in bonding and rebonding:preparation with laser versus conventional acid etch technique显示文摘 | Osagh M Pakshir H R Najafi H Z | 2013 | Photomed Laser Surg2013，31，8： | 1 |
| 20 | Speciation of Cr(Ⅵ)/Cr(Ⅲ) in environmental waters by fluorimetric method using central composite,full and fractional factorial design显示文摘 | MASSUMI A NAJAFI N M BARZEGARI H | 2002 | Microchem J2002，72，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员