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| 1 | Toxicity assessment of polyethylene microplastics in combination with a mix of emerging pollutants on Physalaemus cuvieri tadpoles显示文摘Studies in recent years have shown that aquatic pollution by microplastics(MPs)can be considered to pose additional stress to amphibian populations.However,our knowledge of how MPs affect amphibians is very rudimentary,and even more limited is our understanding of their effects in combination with other emerging pollutants.Thus,we aimed to evaluate the possible toxicity of polyethylene MPs(PE-MPs)(alone or in combination with a mix of pollutants)on the health of Physalaemus cuvieri tadpoles.After 30 days of exposure,multiple biomarkers were measured,including morphological,biometric,and developmental indices,behavioral parameters,mutagenicity,cytotoxicity,antioxidant and cholinesterase responses,as well as the uptake and accumulation of PE-MPs in animals.Based on the results,there was no significant change in any of the parameters measured in tadpoles exposed to treatments,but induced stress was observed in tadpoles exposed to PE-MPs combined with themixture of pollutants,reflecting significant changes in physiological and biochemical responses.Through principal component analysis(PCA)and integrated biomarker response(IBR)assessment,effects induced by pollutants in each test group were distinguished,confirming that the exposure of P.cuvieri tadpoles to the PE-MPs in combination with a mix of emerging pollutants induces an enhanced stress response,although the uptake and accumulation of PE-MPs in these animalswas reduced.Thus,our study provides newinsight into the danger to amphibians of MPs coexisting with other pollutants in aquatic environments. | Amanda Pereira da Costa Araújo Thiarlen Marinho da Luz Mohamed Ahmed Ibrahim Ahmed Mir Mohammad Ali Md.Mostafizur Rahman Bojan Nataraj Daniela de Melo e Silva DamiàBarceló Guilherme Malafaia | 2023 | Journal of Environmental Sciences2023，，5： | 2 |
| 2 | Parkinson's disease,stroke,and related epidemiology显示文摘 | Nataraj A Rajput AH | 2005 | Mov Disord2005，20，11： | 1 |
| 3 | On the interaction of torsion and bending in rotating shafts显示文摘 | | 1993 | Journal of Applied Mechanics1993，60，1： | 1 |
| 4 | Use of particle swarm optimization for machinery fault detection显示文摘 | SAMANTA B NATARAJ C | 2009 | Engineering Applications of Artificial Intelligence2009，，22： | 1 |
| 5 | Investigations of pile foundations in brownfields显示文摘 | Ranian Satyamurthy Mysore S Nataraj Kenneth LMcmanis | 2008 | Journal of Geotechnical and Geoenvironmental Engineering2008，，10： | 1 |
| 6 | On the Interaction of Torsion and Bending in Rotat- ing Shafts 显示文摘 | Nataraj C | 1993 | Journal of Applied Mechanics1993，60，3： | 1 |
| 7 | Mangiferin attenuates MPTP induced dopaminergic neurodegeneration and improves motor impair- ment,redox balance and Bel-2/Bax expression in experimental Par- kinson' s disease mice 显示文摘 | Kavitha M Nataraj J Essa MM | 2013 | Chem Biol Interact2013，206，2： | 1 |
| 8 | Idiopathic pulmonary fibrosis is associated with endothelial to mesenchymal transition显示文摘 | Nataraj D Ernst A Kalluri R | | 0，，： | 1 |
| 9 | Efficient mining of large maximal Bi- cliques from 3D symmetric adjacency matrix 显示文摘 | Selvan S Nataraj RV | 2010 | IEEE Trans on Knowledge and Data Engineering2010，22，12： | 1 |
| 10 | An Improved Interval Global Opti-mization Algori thm Using Higher-order Inclusion Function Forms显示文摘 | Nataraj P S V Kotecha K | 2005 | Journal of Global Optimi zation2005，，32： | 1 |
| 11 | Use of particle swarm optimization for machinery fault detection 显示文摘 | Samanta B Nataraj C | 2009 | Engineering Applications of Artificial Intelligence2009，22，： | 1 |
| 12 | Nonlinear mathematical modeling of butterfly valves driven by solenoid actuators显示文摘 | Peiman N Nataraj C | | 0，，05： | 1 |
| 13 | Angiotensin 1I regulates cellular immune responses through a calcineurin dependent pathway 显示文摘 | Nataraj C Oliverio MI Mannon RB | 1999 | J Clin Invest1999，104，12： | 1 |
| 14 | Utility of microscopic ob-servation of drug susceptibility(MODS)assay for Mycobacteri-um tuberculosis in resource constrained settings显示文摘 | Limaye K Kanade S Nataraj G | 2010 | Indian JTuberc2010，57，4： | 1 |
| 15 | Angiotensin 1I regu- lates cellular immune responses through a calcineurin-dependent pathway显示文摘 | Nataraj C Oliverio MI Mannon RB | 1999 | J Clin Invest1999，104，12： | 1 |
| 16 | Profile modification-a design approach for increasing the tooth strength in spur gear显示文摘 | SANKAR S NATARAJ M | 2011 | Internationnal Journal of Advanced Manufacturing technology2011，55，1： | 1 |
| 17 | Receptors for prostaglandin E2 that regulate cellular responses in the mouse显示文摘 | Thomas DW Tilley ST | 2001 | J Clin Invest2001，108，： | 1 |
| 18 | Periodic solutions in rotor dynamic systems with nonlinear support: a general approach显示文摘 | Nataraj C Nelson H D | 1989 | 111: 187~1931989，111，： | 1 |
| 19 | Detection of Mycobacterium tuberculosisin clinical samples by two-step PCR and nonisotopic hybridization methods 显示文摘 | Shawer R M El-Zatarri F A K Nataraj A | 1993 | J ClinMicrobiol1993，31，： | 1 |
| 20 | The dynamic of a rotor system with a cracked shaft显示文摘 | NELSON H D NATARAJ C | | 0，，： | 1 |
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