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| 1 | Clinical and pathological characterization of epstein-barr virus-associated gastric carcinomas in portugal显示文摘AIM To determine the prevalence of epstein-barr virus(eb V)-associated gastric carcinomas in the North Region of Portugal and to study its clinicopathological characteristics. METHODS We have performed a retrospective study including a total of 179 consecutive patients with gastric cancer(GC) submitted to gastrectomy during 2011 at the Portuguese Oncology Institute of Porto. Clinical and pathological data was collected from individual clinical records and inserted on a database with unique codification. Tumour tissues were collected from the institutional tumour bank. eb V was detected by in situ hybridization for the detection of eb V-encoded small RNAs(ebe Rs) and eb V latent proteins(LMP1 and LMP2 A) were detected by immunohistochemistry.RESULTS The analysis showed that eb V-associated gastric carcinomas(eb Va GC) represents 8.4%(15/179) of all GC cases, with a significant differential distribution among histological types(P < 0.001): 100%(3/3) of medullary carcinomas, 100%(1/1) of adenosquamous carcinoma, 8.7%(8/92) of tubular adenocarcinomas, 8.0%(2/25) of mixed carcinomas and 2%(1/51) in poorly cohesive carcinomas. The analysis revealed a higher predominance of eb Va GC in the upper third and middle(cardia, fundus and body) of the stomach(P = 0.041), a significant lower number of regional lymph nodes invasion(P = 0.025) and a tendency for better prognosis(P = 0.222). eb V latent protein expression revealed that all eb Va GC cases were LMP1-negative, nevertheless 6 cases(40%) expressed LPM2 A, which reveals that these cases show a distinct eb V-Latency profile(latency II-like).CONCLUSION eb Va GC represents 8.4% of all GC in the North Region of Portugal. The eb V-infected patients have specific clinic-pathological features that should be further explored to develop new strategies of management and treatment. | Joana Ribeiro Andreia Oliveira Mariana Malta Claudia Oliveira Fernanda Silva Ana Galaghar Luís Pedro Afonso Maria Cassiano Neves Rui Medeiros Pedro Pimentel-Nunes Hugo Sousa | 2017 | World Journal of Gastroenterology2017，23，40： | 9 |
| 2 | Detection of flock movement and behaviour of broiler chickens at different feeders using image analysis显示文摘The behaviour of broiler chickens has been extensively studied as a function of stocking density and environmental conditions,but limited information was reported in the scientific literature about the effect of feeder type on birds’feeding process.The main objective of this study was to assess the effects of three different feeder types in relation to the birds’behaviour in its surroundings.The analysed feeders were:tube-type with partition grid(F1);tube-type without partition grid(F2);and automatic type with partition grid(F3).The considered variables were:occupied area(OA);activity index(AI)(flock movement);total birds presented in the area(TB);and birds effectively eating(EE).OA and AI were calculated by computational image analysis while TB and EE were manually measured.The results indicated that the feeder type could have influenced the birds’behaviour regarding to OA(R2=0.56),TB(R2=0.48),and EE(R2=0.40),but AI(R2=0.01)was not found to be directly influenced by the feeder type.A higher percentage of birds effectively eating were found in F2(86.4%),which was the one with the largest free area to access the feed.Similar average number of total birds was found in F1,but with a lower percentage of individuals effectively eating(63.3%),which means that birds were nearby this feeder performing other behaviours.Since the assessed feeders were in the same house under the same conditions,it can be suggested that not only the free area to access the feed but potentially the design of feeders could have influenced the birds’feeding preference.The real beneficial effect of the adoption of partition grid on feed trays is still uncertain,and it is also unclear whether the financial value of reduced wastage would compensate the possible reduction in feed intake. | Diego Pereira Neves Saman Abdanan Mehdizadeh Matthew Tscharke Irenilza de Alencar Nääs Thomas Michael Banhazi | 2015 | Information Processing in Agriculture2015，2，3： | 4 |
| 3 | Clinical delivery of int ensity modulated conformal radiotherapy or second-primary head and neck cancer using a multileaf collimator with dynamic control 显示文摘 | Neve WD Gersem WD Derycke S | 1999 | Radi other Oncol,1999，50，： | 1 |
| 4 | Role of DNA methylation in miR- 200c/141 cluster silencing in invasive breast cancer cells 显示文摘 | Neves R Scheel C Weinhold S | 2010 | BMC Res Notes2010，3，： | 1 |
| 5 | Opti- mum maintenance strategy for deteriorating bridge structures based on lifetime functions显示文摘 | YANG S I FRANGOPOL D M NEVES L C | 2006 | Engineering Structures2006，28，2： | 1 |
| 6 | Influence of soil compaction on carbon and nitrogen mineralization of soil organic matter and crop residues显示文摘 | De Neve S Hofman G | 2000 | Biol Fertil Soils2000，，30： | 1 |
| 7 | Role of DNA methylation in miR-200c/141 cluster silencing in invasive breast cancer cells显示文摘 | Neves R Scheel C Weinhold S | 2010 | BMC Res Notes2010，3，： | 1 |
| 8 | Molecular and ultrastructural characterisation of EspA from different enteropathogenic Escherichia coli serotypes显示文摘 | Knutton S Trabulsi LR | 1998 | FEMS Microbiol Lett1998，169，： | 1 |
| 9 | Screening of five essential oils for identification of potential inhibitors of IL- 1-induced Nf-kappaB activation and NO production in human chondrocytes: characterization of the inhibitory activity of alpha-pinene 显示文摘 | Neves A Rosa S Gonqalves J | 2010 | Planta Med2010，76，3： | 1 |
| 10 | Cardiovascular risk in peritoneal dialysis-a Portuguese multicenter study显示文摘 | Neves M Machado S Rodrigues L | 2014 | Nefrologia2014，34，2： | 1 |
| 11 | Service life prediction of structural systems using lifetime func- tions with emphasis on bridges显示文摘 | YANG S I FRANGOPOL D M NEVES L C | 2004 | Reliability Engineer- ing & System Safety2004，86，1： | 1 |
| 12 | Granule Cell Dispersion is Associated with Memory Impairment in Right Mesial Temporal Lobe Epilepsy显示文摘 | NEVES R S TUDESCO I JARDIM A P | 2012 | Seizure2012，21，9： | 1 |
| 13 | Acute renal failure in severely burned patients显示文摘 | Lopes J A Jorge S Neves F C | 2007 | Resuscitation2007，73，2： | 1 |
| 14 | Manipulating the N release from 15N labelled celery residues by using straw and vinasses 显示文摘 | CHAVES B DE NEVE S BOECKX P | 2006 | Soil Biology and Biochemistry2006，38，： | 1 |
| 15 | Spectrophoto- metric flow system using vanadomolybdophosphate detection chemistry and a liquid waveguide capillary cell for the determination of phosphate with improved sensitivity in surface and ground water samples显示文摘 | Neves M S A C Souto M R S | 2008 | Talanta2008，77，： | 1 |
| 16 | N mineralization and nitrate leachingfrom vegetable crop residues under field conditions:a model evalua-tion显示文摘 | DE NEVE S DE HOFMAN G | 1998 | Soil Biology and Biochemistry1998，30，14： | 1 |
| 17 | Electrokinetic characterization of asphaltenes and the asphahenes/ resins interaction 显示文摘 | Gonzalez G Neves G B M Saraiva S M | 2003 | Energy Fuels2003，17，4： | 1 |
| 18 | Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease显示文摘 | Yankner BA Dawes LR Fisher S Villa-Komaroff L Oster-Granite ML Neve RL | 1989 | Science1989，245，： | 1 |
| 19 | Nitrogen and phosphorus balances of Hungarian farms显示文摘 | D'haene K Magyar M De Neve S | 2007 | European Journal of Agronomy2007，26，3： | 1 |
| 20 | Detection of potential fracture and small faults using seismic attributes 显示文摘 | Neves F A Zahrani M S Bremkamp S W | 2004 | The Leading Edge2004，23，9： | 1 |
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