|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Pathogenesis and clinical management of Helicobacter pylori gastric infection显示文摘Helicobacter pylori(H.pylori)is a gram-negative bacterium that infects approximately 4.4 billion individuals worldwide.However,its prevalence varies among different geographic areas,and is influenced by several factors.The infection can be acquired by means of oral-oral or fecal-oral transmission,and the pathogen possesses various mechanisms that improve its capacity of mobility,adherence and manipulation of the gastric microenvironment,making possible the colonization of an organ with a highly acidic lumen.In addition,H.pylori presents a large variety of virulence factors that improve its pathogenicity,of which we highlight cytotoxin associated antigen A,vacuolating cytotoxin,duodenal ulcer promoting gene A protein,outer inflammatory protein and gamma-glutamyl transpeptidase.The host immune system,mainly by means of a Th1-polarized response,also plays a crucial role in the infection course.Although most H.pylori-positive individuals remain asymptomatic,the infection predisposes the development of various clinical conditions as peptic ulcers,gastric adenocarcinomas and mucosa-associated lymphoid tissue lymphomas.Invasive and non-invasive diagnostic methods,each of them with their related advantages and limitations,have been applied in H.pylori detection.Moreover,bacterial resistance to antimicrobial therapy is a major challenge in the treatment of this infection,and new therapy alternatives are being tested to improve H.pylori eradication.Last but not least,the development of effective vaccines against H.pylori infection have been the aim of several research studies. | Breno Bittencourt de Brito Filipe Ant?nio Fran?a da Silva Aline Silva Soares Vinícius Afonso Pereira Maria Luísa Cordeiro Santos Mariana Miranda Sampaio Pedro Henrique Moreira Neves Fabrício Freire de Melo | 2019 | World Journal of Gastroenterology2019，25，37： | 84 |
| 2 | The 2828 cm^-1 C-H Related IR Vibration in CVD Diamond显示文摘 | Tang C J Neves A J Rino L | 2004 | Diamond and Related Materials2004，13，48： | 1 |
| 3 | Severe paraquat poisoning: clinical and radiological findings in a survivor 显示文摘 | Neves FF Sousa RE Pazin-Filho A | 2010 | J Bras Pneumol2010，36，： | 1 |
| 4 | Probabilistic lifetime-oriented multiobjective optimi- zation of bridge maintenance: single maintenance type 显示文摘 | NEVES LC FRANGOPOL D M PETCHERDCHOO A | 2006 | Journal of Structural Engineering2006，132，6： | 1 |
| 5 | A2 copper(II) pyridinium salts, from ionic liquids to layered solids to liquid crystals显示文摘 | Neve F Francescangeli O Crispini A Charmant J | 2001 | Chem Mater2001，13，6： | 1 |
| 6 | Characterization and prediction of biomass pyrolysis products显示文摘 | NEVES D THUNMAN H MATOS A | 2011 | Progress in Energy and Combustion Science2011，37，5： | 1 |
| 7 | Development of the soil macrofauna community under silvopastoral and agrosilvieultural systems in Amazonia显示文摘 | Barros E Neves A Blanchart E | 2003 | Pedobiologia2003，47，3： | 1 |
| 8 | Pulsed-field gel electrophoresis(PFGE) analysis of Listeria monocytogenes isolates from different sources and geographical origins and representative of the twelve serovars 显示文摘 | Neves E Lourenco A Silva A C | 2008 | Syst Appl Microbiol2008，31，5： | 1 |
| 9 | The surface antigen SAG3 me- diates the attachment of Toxoplasma gondii to cell-surface proteogly- cans显示文摘 | Jacquet A Coulon L De Neve J | 2001 | Mol Biochem Parasitol2001，116，1： | 1 |
| 10 | Crystal architecture and mesophase structure of long-chain N-alkylpyridinium tetrachlo- rometallates显示文摘 | Neve F Francescangeli O Crispini A | 2002 | Inorg Chim Acta2002，338，： | 1 |
| 11 | Static free vibration and buckling analysis of isotropic and sandwich functionally graded plates using a quasi-3D higher- order shear deformation theory and a meshless technique 显示文摘 | NEVES A M A FERREIRA A J M CARRERA E | 2012 | Composites: Part B2012，89，： | 1 |
| 12 | In situ structural evolution of arc-deposited Cr-based coatings显示文摘 | Neves A M Severo V Cvr(c)ek L | 2008 | Surface & Coatings Technology2008，202，55： | 1 |
| 13 | Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling显示文摘 | Pu Q Neves MF Virdis A | 2003 | Hypertension2003，42，： | 1 |
| 14 | Fusion to green fluorescent protein improves expression levels of Theileria parva sporozoite surface antigen p67 in insect cells显示文摘 | Kaba SA Neve V Musoke A J | | 0，，： | 1 |
| 15 | Screening of five essential oils for identification of potential inhibitors of IL- 1-induced Nf-kappaB activation and NO production in human chondrocytes: characterization of the inhibitory activity of alpha-pinene 显示文摘 | Neves A Rosa S Gonqalves J | 2010 | Planta Med2010，76，3： | 1 |
| 16 | Expression of vascular endothelial growth factor in normal, osteoarthritic and os- teoporotic osteoblasts 显示文摘 | Corrado A Neve A Cantatore FP | 2013 | Clin Exp Med2013，13，： | 1 |
| 17 | Endothelium - Restricted Overexpression of Human Endotbelin - 1 Causes Vascular Remodeling and Endothelial Dysfunction 显示文摘 | Amiri F Virdis A Neves MF | 2004 | Circulation2004，110，： | 1 |
| 18 | Endothelium-restricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction显示文摘 | Amiri F Virdis A Neves MF | 2004 | Circulation2004，110，15： | 1 |
| 19 | Endothelium-Restricted Over-expression of Human Endothelin-1 Causes Vascular Remodeling and Endothelial Dysfunction显示文摘 | Amiri F Virdis A Neves MF | 2004 | Circulation2004，110，15： | 1 |
| 20 | Granule Cell Dispersion is Associated with Memory Impairment in Right Mesial Temporal Lobe Epilepsy显示文摘 | NEVES R S TUDESCO I JARDIM A P | 2012 | Seizure2012，21，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员