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	题名	作者	年代	出处	被引量
1	Rabeprazole vs esomeprazole in non-erosive gastro-esophageal reflux disease: A randomized, double-blind study in urban Asia显示文摘AIM:Gastro-esophageal reflux disease (GERD) is becoming increasingly common in Asia. Data on the efficacy of proton pump inhibitors in patients with non-erosive GERD (NERD)in Asia is lacking. This double-blind study compared the efficacy and safety of rabeprazole with esomeprazole in relief of symptoms in patients with NERD.METHODS: One hundred and thirty-four patients with reflux symptoms of NERD and normal endoscopy were randomized to receive rabeprazole 10 mg or esomeprazole 20 mg once daily for 4 wk. Symptoms were recorded in a diary and changes in severity of symptoms noted.RESULTS: At 4 wk of treatment, rabeprazole 10 mg and esomeprazole 20 mg were comparable with regards to the primary endpoint of time to achieve 24-h symptomfree interval for heartburn 8.5 d vs9 d and regurgitation 6 d vs 7.5 d. Rabeprazole and esomeprazole were also similarly efficacious in term of patient's global evaluation with 96% of patients on rabeprazole and 87.9% of patients on esomeprazole, reporting that symptoms improved(P=NS). Satisfactory relief of day- and night-time symptoms was achieved in 98% of patients receiving rabeprazole and 81.4% of patients receiving esomeprazole. Adverse events were comparable in both groups (P = NS).CONCLUSION: Rabeprazole 10 mg has a similar efficacy and safety profile in Asians with NERD as esomeprazole 20 mg. Further study is necessary to investigate whether the small differences between the two drugs seen in this study are related to the improved pharmacodynamicpro perties of rabeprazole. Both drugs were well tolerated.	KM Fock EK Teo TL Ang TS Chua TM Ng YL Tan	2005	World Journal of Gastroenterology2005，11，20：	8
2	Signal transduction through MAP kinase cascades显示文摘	Lewis TS Shapiro PS Ahn NG	1998	Adv Cancer Res1998，74，：	1
3	Prognostic factors of locoregionally recurrent nasopharyngeal carcinoma-a retrospective review of 182 cases显示文摘	Yang TS Ng KT Wang HM	1996	Am J Clin Oncol1996，19，4：	1
4	Signal transduction through MAP kinase cascades显示文摘	Lewis TS Shapiro PS Ahn NG		0，，：	1
5	An affine adjustable robust model for gen- eration and transmission network planning显示文摘	NG TS SY C	2014	Electrical Power and Energy Systems2014，60，：	1
6	Signal transduction through MAP kinase cascades显示文摘	Lewis TS Shapiro PS Ahn NG	1998	Adv Cancer Res1998，74，：	1
7	Sputum bacteriology in patients with acute exacerbations of COPD in Hong Kong 显示文摘	KO FW Ng TK Li TS	2005	Respir Med2005，99，4：	1
8	Could formant frequency of snore signals be an alternative means for the diagnosis of obstructive sleep apnea显示文摘	Ng AK Koh TS Baey E	2008	Sleep Med2008，9，：	1
9	An alternative early knee flexion regimen of continuous passive motion for total knee arthroplasty显示文摘	Ng TS Yeo SJ	1999	Physiotherapy Singapore1999，2，：	1
10	A new 25-Gauge instrument system for transconjunctival sutureless vitrectomy surgery显示文摘	Fujii GY De Juan E Jr Humayun MS Pieramici DJ Chang TS Awh C Ng E Barnes A Wu SL Sommerville DN		0，，10：	1
11	Morphology,drug distribution,and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/eva-poration method显示文摘	Yang YY Chung TS Ping Ng	2001	Biomaterials2001，22，3：	1
12	Family-based prevention of mental health problems in children affected by HIV and AIDS 显示文摘	Betancourt TS Ng LC Kirk CM	2014	AIDS2014，28，3：	1
13	Prognostic factors of locoregionally recurrent nasopharyngeal carcinoma a retrospective review of 182 cases显示文摘	Yang TS Ng KT Wang Hm	1996	Am J Clin onco11996，19，4：	1
14	Simplifying four-strand flexor tendonrepair using double-stranded suture: a comparative ex vivo study ontensile strength and bulking显示文摘	Low TH Ahmad TS Ng ES	2012	J Hand Surg Eur2012，37，9：	1
15	Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method显示文摘	Yang Yi-yan Chung TS Ng NP	2001	Biomaterials2001，22，3：	1
16	Signal transduction through MAP kinase casecades显示文摘	Lewis TS Shapiro PS Ahn NG		0，，：	1
17	Imatinib(STI-571) heals a gastrocutaneous fistula resulting from a malignant gastric stromal tumor显示文摘	EK Ng SK Wong TS Mok	2003	Gastric Cancer January 12003，6，2：	1
18	A comparison of postoperative cognitive function and pain relief with fentanyl or tramadol patient-controlled analgesia显示文摘	Ng KF Yuen TS Ng VM	2006	J Clin Anesth2006，18，20：	1
19	Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/ evaporation method显示文摘	Yang YY Chung TS Ng NP	2001	Biomaterials2001，22，3：	1
20	Preferential cytotoxicity of cells transduced with cytosine deaminase compared to bystander ceils after treatment with 5-flucytosine 显示文摘	Lawrence TS Rehemtulla A Ng EY	1998	Cancer Res1998，58，12：	1

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