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| 1 | 专用气候数据空间插值软件ANUSPLIN及其应用显示文摘空间化的气候数据作为环境因子参数是区域气候模型和地学模型的基础,而插值软件是实现气候观测点数据空间化的工具。ANUSPLIN基于薄盘样条函数理论,引入多个影响因子作为协变量进行气象要素空间插值,大大提高插值精度,且能同时进行多个表面的空间插值,对时间序列的气象要素更加适合。 | 刘志红 Tim R. McVicar Van Niel T. G 杨勤科 李锐 | 2008 | 气象2008，34，2： | 180 |
| 2 | 水文地貌关系正确DEM的建立方法显示文摘水文地貌关系正确DEM(hydrologically correct DEMs,Hc-DEM),是指符合水文地貌学基本原理,正确反映水文要素(水流方向、水流路径、水系网络、流域界线等)与地貌特征发生和位置关系的DEM。区域尺度水文和土壤侵蚀等研究中,地形因子参数只能利用DEM来提取,为了准确反映地面形态,有效提取地貌和水文特征因子,建立Hc-DEM是必需的。笔者对Hc-DEM的概念、建立方法进行了讨论和介绍;以黄土高原为例,提出了利用多种比例尺数字地形图和ANUDEM软件建立DEM的关键参数;通过与TIN方法建立的DEM的比较,对所建立的DEM进行了简要评价。研究表明,利用我国已有的数字地形图和ANUDEM软件,可以建立Hc-DEM,为流域水文和区域尺度水土流失定量分析模拟、区域尺度植被适宜性评价等研究提供更加直接的数据支持。 | 杨勤科 师维娟 Tim R.McVicar Tom G.Van Niel Lingtao Li | 2007 | 中国水土保持科学2007，5，4： | 41 |
| 3 | The clinical impact of bacterial biofilms显示文摘Bacteria survive in nature by forming biofilms on surfaces and probably most, if not all, bacteria (and fungi) are capable of forming biofilms. A biofilm is a structured consortium of bacteria embedded in a self-produced polymer matrix consisting of polysaccharide, protein and extracellular DNA. Bacterial biofilms are resistant to antibiotics, disinfectant chemicals and to phagocytosis and other components of the innate and adaptive inflammatory defense system of the body. It is known, for example, that persistence of staphylococcal infections related to foreign bodies is due to biofilm formation. Likewise, chronic Pseudomonas aeruginosa lung infections in cystic fibrosis patients are caused by biofilm growing mucoid strains. Gradients of nutrients and oxygen exist from the top to the bottom of biofilms and the bacterial cells located in nutrient poor areas have decreased metabolic activity and increased doubling times. These more or less dormant cells are therefore responsible for some of the tolerance to antibiotics. Biofilm growth is associated with an increased level of mutations. Bacteria in biofilms communicate by means of molecules, which activates certain genes responsible for production of virulence factors and, to some extent, biofilm structure. This phenomenon is called quorum sensing and depends upon the concentration of the quorum sensing molecules in a certain niche, which depends on the number of the bacteria. Biofilms can be prevented by antibiotic prophylaxis or early aggressive antibiotic therapy and they can be treated by chronic suppressive antibiotic therapy. Promising strategies may include the use of compounds which can dissolve the biofilm matrix and quorum sensing inhibitors, which increases biofilm susceptibility to antibiotics and phagocytosis. | Niels Hoiby Oana Ciofu Helle Krogh Johansen Zhi-jun Song Claus Moser Peter Ostrup Jenser Soren Molin Michael Givskov Tim Tolker-Nieisen Thomas Bjamsholt | 2011 | International Journal of Oral Science2011，3，2： | 48 |
| 4 | Immune regulatory properties of multipotent mesenchymal stromal cells:Where do we stand?显示文摘Multipotent mesenchymal stromal cells (MSC) can be isolated and efficiently expanded from almost every single body tissue and have the ability of self-renewal and differentiation into various mesodermal cell lineages. Moreover, these cells are considered immunologically privileged, related to a lack of surface expression of costimulatory molecules required for complete T cell activation. Recently, it has been observed that MSC are capable of suppressing the immune response by inhibiting the maturation of dendritic cells and suppressing the function of T lymphocytes, B lymphocytes and natural killer cells in autoimmune and inflammatory diseases as a new strategy for immunosuppression. The understanding of immune regulation mechanisms by MSC is necessary for their use as immunotherapy in clinical applications for several diseases. | ênio José Bassi Carlos Alberto Mayora Aita Niels Olsen Saraiva Camara | 2011 | World Journal of Stem Cells2011，3，1： | 27 |
| 5 | Strategies for combating bacterial biofilm infections显示文摘Formation of biofilm is a survival strategy for bacteria and fungi to adapt to their living environment, especially in the hostile environment. Under the protection of biofilm, microbial cells in biofilm become tolerant and resistant to antibiotics and the immune responses, which increases the difficulties for the clinical treatment of biofilm infections. Clinical and laboratory investigations demonstrated a perspicuous correlation between biofilm infection and medical foreign bodies or indwelling devices. Clinical observations and experimental studies indicated clearly that antibiotic treatment alone is in most cases insufficient to eradicate biofilm infections. Therefore, to effectively treat biofilm infections with currently available antibiotics and evaluate the outcomes become important and urgent for clinicians. The review summarizes the latest progress in treatment of clinical biofilm infections and scientific investigations, discusses the diagnosis and treatment of different biofilm infections and introduces the promising laboratory progress,which may contribute to prevention or cure of biofilm infections. We conclude that, an efficient treatment of biofilm infections needs a well-established multidisciplinary collaboration, which includes removal of the infected foreign bodies, selection of biofilm-active,sensitive and well-penetrating antibiotics, systemic or topical antibiotic administration in high dosage and combinations, and administration of anti-quorum sensing or biofilm dispersal agents. | Hong Wu Claus Moser Heng-Zhuang Wang Niels Hφiby Zhi-Jun Song | 2015 | International Journal of Oral Science2015，7，1： | 27 |
| 6 | 基于5变量局部薄盘光滑样条函数的蒸发空间插值显示文摘高分辨率、栅格化的气候数据作为环境因子是地学模型和气候模型等相关研究的重要参数,国内外的研究多集中于温度、降水等气象要素,对陆面蒸发空间化研究较少。对黄土高原多沙粗沙区及周围共计53个气象站点(多沙粗沙区30个)蒸发皿测量值Epan进行空间插值,以5变量局部薄盘样条函数(经纬度为自变量,净辐射、水气压差和风速为协变量),建立具有多元线性子模型的蒸发插值模型,以ANUSPLIN为实现软件,生成连续21年共252个蒸发表面。交叉验证表明:引入蒸发影响因子作为协变量线性子模型进行表面插值能显著提高插值精度,夏季提高幅度更大,拟合表面具有较高的精确度与平滑度。蒸发随协变量的变率显示,在多沙粗沙区,水气压差是夏季蒸发的主要控制因素,风速对蒸发的影响冬季稍强一些,净辐射的影响没有明显的季节性,只在春分和秋分时节有微小提高。 | 刘志红 Tim R.McVicar LingTao Li Tom G.Van Niel 杨勤科 李锐 穆兴民 | 2006 | 中国水土保持科学2006，4，6： | 26 |
| 7 | 细菌生物膜与抗生素耐药显示文摘抗生素耐药已成为一个全球关注的严重问题,也是科学界研究的热点问题.近年来的研究成果揭示,抗生素的耐药问题除了与耐药菌株的大量产生有关外,还与致病菌在人体内以生物膜(biofilms)的方式生长密切相关.生物膜是细菌粘附在物体表面上形成的一种具有高度结构性的膜状复合物,其主要成分为细菌分泌的胞外基质和细菌菌体.生物膜的形成显著增强了生物膜内细菌对抗生素、化学杀菌剂以及机体免疫系统的抵抗能力.结合国外近年来的研究成果,介绍了生物膜的发生发展,阐述了对人类健康的危害,重点讨论了细菌生物膜类感染难以根除的原因和对抗生素耐药的可能机制,并根据其特性对细菌生物膜类感染的防治提出一些看法. | 宋志军 吴红 Michael Givskov Niels Hφiby | 2003 | 自然科学进展2003，13，10： | 22 |
| 8 | Influence of rolling friction on single spout fluidized bed simulation显示文摘In this paper we study the effect of rolling friction on the dynamics in a single spout fluidized bed using Discrete Element Method (DEM) coupled to Computational Fluid Dynamics (CFD). In a first step we neglect rolling friction and show that the results delivered by the open source CFD-DEM framework applied in this study agree with previous simulations documented in literature. In a second step we include a rolling friction sub-model in order to investigate the effect of particle non-sphericity. The influence of particle-particle as well as particle-wall rolling friction on the flow in single spout fluidized bed is studied separately. Adequate rolling friction model parameters are obtained using first principle DEM simulations and data from literature. Finally, we demonstrate the importance of correct modelling of rolling friction for coupled CFD-DEM simulations of spout fluidized beds. We show that simulation results can be improved significantly when applying a rolling friction model, and that experimental data from literature obtained with Positron Emission Particle Tracking (PEPT) technique can be satisfactorily reproduced. | Christoph Goniva Christoph Kloss Niels G. Deen Johannes A.M.Kuipers Stefan Pirker | 2012 | Particuology2012，10，5： | 18 |
| 9 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 10 | Cytoprotective role of heme oxygenase-1 and heme degradation derived end products in liver injury显示文摘The activation of heme oxygenase-1(HO-1) appears to be an endogenous defensive mechanism used by cells to reduce inflammation and tissue damage in a number of injury models. HO-1, a stress-responsive enzyme that catabolizes heme into carbon monoxide(CO), biliverdin and iron, has previously been shown to protect grafts from ischemia/reperfusion and rejection.In addition, the products of the HO-catalyzed reaction, particularly CO and biliverdin/bilirubin, have been shown to exert protective effects in the liver against a number of stimuli, as in chronic hepatitis C and in transplanted liver grafts. Furthermore, the induction of HO-1 expression can protect the liver against damage caused by a number of chemical compounds. More specifically, the CO derived from HO-1-mediated heme catabolism has been shown to be involved in the regulation of inflammation; furthermore, administration of low concentrations of exogenous CO has a protective effect against inflammation. Both murine and human HO-1 deficiencies have systemic manifestations associated with iron metabolism, such as hepatic overload(with signs of a chronic hepatitis) and iron deficiency anemia(with paradoxical increased levels of ferritin).Hypoxia induces HO-1 expression in multiple rodent,bovine and monkey cell lines, but interestingly, hypoxia represses expression of the human HO-1 gene in a variety of human cell types(endothelial cells, epithelial cells, T cells). These data suggest that HO-1 and CO are promising novel therapeutic molecules for patients with inflammatory diseases. In this review, we present what is currently known regarding the role of HO-1 in liver injuries and in particular, we focus on the implications of targeted induction of HO-1 as a potential therapeutic strategy to protect the liver against chemically induced injury. | Clarice Silvia Taemi Origassa Niels Olsen Saraiva Cmara | 2013 | World Journal of Hepatology2013，5，10： | 17 |
| 11 | Gestational diabetes: A clinical update显示文摘Gestational diabetes mellitus(GDM)is increasing in prevalence in tandem with the dramatic increase inthe prevalence of overweight and obesity in women of childbearing age.Much controversy surrounds the diagnosis and management of gestational diabetes,emphasizing the importance and relevance of clarity and consensus.If newly proposed criteria are adopted universally a significantly growing number of women will be diagnosed as having GDM,implying new therapeutic challenges to avoid foetal and maternal complications related to the hyperglycemia of gestational diabetes.This review provides an overview of clinical issues related to GDM,including the challenges of screening and diagnosis,the pathophysiology behind GDM,the treatment and prevention of GDM and the long and short term consequences of gestational diabetes for both mother and offspring. | Ulla Kampmann Lene Ring Madsen Gitte Oeskov Skajaa Ditte Smed Iversen Niels Moeller Per Ovesen | 2015 | World Journal of Diabetes2015，6，8： | 17 |
| 12 | Upper gastrointestinal sensory-motor dysfunction in diabetes mellitus显示文摘胃肠(官方补给) 感觉马达的畸形在有糖尿病的病人是普通的并且可以包含官方补给的道的任何部分。畸形经常是无临床症状的,并且幸好,严重、威胁生活的问题仅仅很少发生。在糖尿病的反常上面的官方补给的感觉马达的功能的致病不完全地被理解并且是最可能的起源多因素。糖尿病的自治神经病以及糖尿病的尖锐非最优的控制被显示了损害官方补给的马达和感觉功能。词法并且官方补给的墙的机械改变在糖尿病的持续时间期间开发的简历,并且可以贡献马达和感觉机能障碍。在感觉的这评论和活动性,在糖尿病的上面的官方补给的道的混乱被讨论;并且与感觉马达的机能障碍有关的机械改变也是的词法变化和简历探讨了。 | Jingbo Zhao Jens Brφndum Frφkjaer Asbjφrn Mohr Drewes Niels Ejskjaer | 2006 | World Journal of Gastroenterology2006，12，18： | 15 |
| 13 | Normal reference ranges for semen quality and their relations to fecundity显示文摘几最近的研究证明了一个人的肥沃每 mL 在 4000 万个精子下面与精子集中日益增多地减少。因此,为精液分析的新世界健康组织指南建议每 mL 从 20 ~ 15 百万个精子为正常精子集中降低更低的截止价值,是不幸的。作为结果,越过世界的 subfertile 人的大组以后不能收到适当 andrological 帮助。 | Niels E. Skakkebaek | 2010 | Asian Journal of Andrology2010，12，1： | 15 |
| 14 | 睾丸活检:临床操作及其诠释显示文摘睾丸活检许多年来被认为是不明病因男性不育和无精症诊断的基础。近来,男性不育指南都限定诊断性睾丸活检只能用于梗阻性无精子症(睾丸体积正常,生殖激素正常)的鉴别诊断。现今,睾丸活检取精技术与胞浆内单精子显微注射(ICSI)联用于非梗阻性无精子症患者的取精过程中。此外,睾丸活检还可以应用于有睾丸恶性肿瘤风险的患者的取精治疗中。研究一些不育男性后发现,不育患者患原位睾丸癌的风险越来越高,尤其是曾有隐睾症、睾丸恶性肿瘤病史,或患睾丸萎缩的患者。睾丸超声异常,比如睾丸微石症,实质内呈弥散分布,软细胞组织不均、睾丸组织损伤等,进一步增加了这些患者原位癌的发病率。准确的组织学分类,正确的组织处理和固定,样品准备和评估是必须的。同时,推荐使用标准的睾丸活检方法。另外,通过免疫组织化学法检测睾丸组织的肿瘤恶化程度是不可缺少的技术支持。本综述主要描述了睾丸活检用于男性不育临床诊断和治疗措施的最新进展。 | Gert R Dohle Saad Elzanaty Niels J van Casteren | 2012 | Asian Journal of Andrology2012，14，1： | 13 |
| 15 | Innate lymphoid cells in tissue homeostasis and diseases显示文摘Innate lymphoid cells(ILCs) are the most recently discovered family of innate immune cells. They are a part of the innate immune system, but develop from the lymphoid lineage. They lack pattern-recognition receptors and rearranged receptors, and therefore cannot directly mediate antigen specific responses. The progenitors specifically associated with the ILCs lineage have been uncovered, enabling the distinction between ILCs and natural killer cells. Based on the requirement of specific transcription factors and their patterns of cytokine production, ILCs are categorized into three subsets(ILC1, ILC2 and ILC3). First observed in mucosal surfaces, these cell populations interact with hematopoietic and non-hematopoietic cells throughout the body during homeostasis and diseases, promoting immunity, commensal microbiota tolerance, tissue repair and inflammation. Over the last 8 years, ILCs came into the spotlight as an essential cell type able to integrate diverse host immune responses. Recently, it became known that ILC subsets play a key role in immune responses at barrier surfaces, interacting with the microbiota, nutrients and metabolites. Since the liver receives the venous blood directly from the intestinal vein, the intestine and liver are essential to maintain tolerance and can rapidly respond to infections or tissue damage. Therefore, in this review, we discuss recent findings regarding ILC functions in homeostasis and disease, with a focus on the intestine and liver. | Aline Ignacio Cristiane Naffah Souza Breda Niels Olsen Saraiva Camara | 2017 | World Journal of Hepatology2017，9，23： | 12 |
| 16 | 磷酸掺杂的ab-PBI膜及其在高温质子交换膜燃料电池中的应用显示文摘以3,4-二氨基苯甲酸为单体合成了ab-聚苯并咪唑. 研究了磷酸掺杂的该质子交换膜在80~200 ℃, 不同湿度以及不同酸掺杂量下的质子电导率. 该质子交换膜可作为燃料电池的膜电解质, 在常压不增湿的条件下, 可使电池运行温度达到200 ℃. | 何荣桓 李庆峰 Bjerrum Niels J. | 2005 | 高等学校化学学报2005，26，12： | 11 |
| 17 | 胡杨(Populus euphratica Oliv.)根繁殖特征显示文摘以新疆塔里木河中游河岸北部河漫滩的胡杨幼林带为对象,从克隆生态学的角度,采用挖掘法、高压冲洗法及断根胁迫实验,研究了胡杨在资源异质环境中的风险分担、资源觅食与保持功能以及根源性克隆生长形态特征。结果表明:胡杨的地下根分枝类型为单轴型,同一生长方向2水平根的夹角平均约为180°,水平根与垂直根的夹角为90°~100°,水平根和垂直根的空间构型近似T形;基株的胚根周长>分株的次根周长;水平根呈侧圆台形,胡杨的2水平根之间存在着养分的传递。 | 王永斌 努尔巴依.阿布都沙力克 Niels Thevs | 2007 | 生态学杂志2007，26，12： | 11 |
| 18 | Intestinal barrier: A gentlemen's agreement between microbiota and immunity显示文摘Our body is colonized by more than a hundred trillion commensals, represented by viruses, bacteria and fungi. This complex interaction has shown that the microbiome system contributes to the host's adaptation to its environment, providing genes and functionality that give flexibility of diet and modulate the immune system in order not to reject these symbionts. In the intestine,specifically, the microbiota helps developing organ structures, participates of the metabolism of nutrients and induces immunity. Certain components of the microbiota have been shown to trigger inflammatory responses, whereas others, anti-inflammatory responses.The diversity and the composition of the microbiota,thus, play a key role in the maintenance of intestinal homeostasis and explain partially the link between intestinal microbiota changes and gut-related disorders in humans. Tight junction proteins are key molecules for determination of the paracellular permeability. In the context of intestinal inflammatory diseases, the intestinal barrier is compromised, and decreased expression and differential distribution of tight junction proteins is observed. It is still unclear what is the nature of the luminal or mucosal factors that affect the tight junctionproteins function, but the modulation of the immune cells found in the intestinal lamina propria is hypothesized as having a role in this modulation. In this review,we provide an overview of the current understanding of the interaction of the gut microbiota with the immune system in the development and maintenance of the intestinal barrier. | Andrea Moro Caricilli Angela Castoldi Niels Olsen Saraiva Cmara | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，1： | 11 |
| 19 | Occurrence of Aflatoxin B_(1),deoxynivalenol and zearalenone in feeds in China during 2018-2020显示文摘Background:The current study was conducted to investigate the individual and combined occurrence of aflatoxin B_(1)(AFB_(1)),deoxynivalenol(DON)and zearalenone(ZEN)in feeds from various Provinces of China during 2018 to 2020.A total of 3,507 feed samples,including 2,090 feed ingredients and 1,417 complete feed samples,were collected from different areas of China for mycotoxins analysis.Results:The individual contamination of AFB_(1),DON and ZEN were present in more than 81.9%,96.4% and 96.9% of feed samples,respectively,with average concentration ranges of AFB_(1) between 1.2-27.4μg/kg,DON between 458.0-1,925.4μg/kg and ZEN between 48.1-326.8μg/kg.Notably,0.9%,0.5% and 0.1% of feed ingredients,and 1.2-12.8%,0.9-2.9% and 0-8.9% of complete feeds for pigs,poultry and ruminants with AFB_(1),ZEN and DON that exceeded China’s safety standards,respectively.Moreover,more than 81.5%of feed ingredients and 95.7% of complete feeds were co-contaminated with various combinations of these mycotoxins.Conclusion:This study indicates that the feeds in China were universally contaminated with AFB_(1),DON and ZEN during the past 3 years.These findings highlight the significance of monitoring mycotoxin contaminant levels in the domestic animal feed,and the importance of carrying out feed administration and remediation strategies for mycotoxin control. | Ling Zhao Lei Zhang Zijian Xu Xingda Liu Liyuan Chen Jiefan Dai Niel Alexander Karrow Lvhui Sun | 2022 | Journal of Animal Science and Biotechnology2022，13，1： | 10 |
| 20 | Obese diet-induced mouse models of nonalcoholic steatohepatitis-tracking disease by liver biopsy显示文摘AIM:To characterize development of diet-induced nonalcoholic steatohepatitis(NASH)by performing live biopsy in wild-type and genetically obese mice.METHODS:Male wild-type C57BL/6J(C57)mice(DIO NASH)and male Lep ob/Lep ob(ob/ob)mice(ob/ob-NASH were maintained on a diet high in trans-fat(40%)fructose(22%)and cholesterol(2%)for 26 and 12 wk respectively.A normal chow diet served as control in C57 mice(lean chow)and ob/ob mice(ob/ob chow)After the diet-induction period,mice were liver biopsied and a blinded histological assessment of steatosis and fibrosis was conducted.Mice were then stratified into groups counterbalanced for steatosis score and fibrosi stage and continued on diet and to receive daily PO dosing of vehicle for 8 wk.Global gene expression in liver tissue was assessed by RNA sequencing and bioin formatics.Metabolic parameters,plasma liver enzyme and lipids(total cholesterol,triglycerides)as well a hepatic lipids and collagen content were measured b biochemical analysis.Non-alcoholic fatty liver disease activity score(NAS)(steatosis/inflammation/ballooningdegeneration)and fibrosis were scored.Steatosis and fibrosis were also quantified using percent fractional area.RESULTS:Diet-induction for 26 and 12 wk in DIONASH and ob/ob-NASH mice,respectively,elicited progressive metabolic perturbations characterized by increased adiposity,total cholesterol and elevated plasma liver enzymes.The diet also induced clear histological features of NASH including hepatosteatosis and fibrosis.Overall,the metabolic NASH phenotype was more pronounced in ob/ob-NASH vs DIO-NASH mice.During the eight week repeated vehicle dosing period,the metabolic phenotype was sustained in DIO-NASH and ob/ob-NASH mice in conjunction with hepatomegaly and increased hepatic lipids and collagen accumulation.Histopathological scoring demonstrated significantly increased NAS of DIO-NASH mice(0 vs4.7±0.4,P<0.001 compared to lean chow)and ob/ob-NASH mice(2.4±0.3 vs 6.3±0.2,P<0.001compared to ob/ob chow),respectively.Furthermore,fibrosis stage was significantly elevated for DIO-NASH mice(0 vs 1.2±0.2,P<0.05 compared to lean chow)and ob/ob NASH(0.1±0.1 vs 3.0±0.2,P<0.001compared to ob/ob chow).Notably,fibrosis stage was significantly(P<0.001)increased in ob/ob-NASH mice,when compared to DIO-NASH mice.CONCLUSION:These data introduce the obese dietinduced DIO-NASH and ob/ob-NASH mouse models with biopsy-confirmed individual disease staging as a preclinical platform for evaluation of novel NASH therapeutics. | Maria Nicoline Baandrup Kristiansen Sanne Skovgard Veidal Kristoffer Tobias Gustav Rigbolt Kirstine Sloth Tolbol Jonathan David Roth Jacob Jelsing Niels Vrang Michael Feigh | 2016 | World Journal of Hepatology2016，8，16： | 10 |
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