|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 脉冲电场治疗黑色素瘤可破坏肿瘤血供,导致肿瘤完全消退显示文摘A new pulsed electric field therapy for melanoma disrupts the tumor's blood supply and causes complete remission without recurrence. Nuccitelli R, Chen X, Pakhomov AG, et al. Int J Cancer, 2009, 125(2):438-445. | Nuccitelli R Chen X Pakhomov AG | 2009 | 中国口腔颌面外科杂志2009，7，4： | 32 |
| 2 | Physical activity support or weight loss counseling for nonalcoholic fatty liver disease?显示文摘AIM:To determine the clinical effectiveness of intense psychological support to physical activity(PA)in nonalcoholic fatty liver disease(NAFLD),compared with cognitive-behavioral treatment(CBT).METHODS:Twenty-two NAFLD cases received support to exercise,tailored to their motivational needs(PA group).The effects on body weight,physical fitness[6-min walk test,VO2max and the PA-rating(PA-R)questionnaire]and body fat(fatty liver indices and visceral adiposity index)were compared with data obtained in 44 NAFLD subjects enrolled in a CBT program for weight loss,after adjustment for propensity score,calculated on baseline data.Measurements were performed at baseline,at 4-mo and one-year follow-up.Changes in anthropometric,biochemical and PA parameters were tested by repeated measurement ANOVA.Outcome results were tested by logistic regression analysis.RESULTS:At the end of the intensive program,BMI was less significantly reduced in the PA group(-1.09±1.68 kg/m2 vs-2.04±1.42 kg/m2 in the CBT group,P=0.019)and the difference was maintained at 1-year follow-up(-0.73±1.63 vs-1.95±1.88,P=0.012)(ANOVA,P=0.005).PA-R was similar at baseline,when only 14%of cases in PA and 36%in CBT(P=0.120)recorded values≥3.At 4 mo,a PA-R≥3 was registered in 91%of PA and 46%of CBT,respectively(P<0.001)and PA-R≥5(up to 3 h/wk of moderate-toheavy intensity physical activity)was registered in 41%of PA and only 9%of CBT group(P<0.007).The6-min walk test increased by 139±26 m in PA and by only 43±38 m in CBT(P<0.001)and VO2max by8.2±3.8 mL/kg per minute and 3.3±2.7 mL/kg per minute,respectively(P<0.002).After adjustment for propensity,weight loss>7%was significantly associated with CBT group at one year(OR=6.21;95%CI:1.23-31.30),whereas PA-R>3 was associated with PA group(10.31;2.02-52.63).Liver enzymes decreased to values within normal limits in 36%of PA cases and61%of CBT(P<0.070).Estimated liver fat(Kotronen index)fell below the fatty liver threshold in 36%of PA and 34%and CBT cases at one-year(not different).Also the fatty liver index and the visceral adiposity index improved to a similar extent.CONCLUSION:Intensive psychological counseling for PA produces hepatic effects not different from standard CBT,improving physical fitness and liver fat independent of weight loss.Strategies promoting exercise are worth and effective in motivated patients,particularly in lean NAFLD patients where large weight loss cannot be systematically pursued. | Luca Montesi Chiara Caselli Elena Centis Chiara Nuccitelli Simona Moscatiello Alessandro Suppini Giulio Marchesini | 2014 | World Journal of Gastroenterology2014，20，29： | 3 |
| 3 | ZAP: extreme voltage could be a surprisingly delicate tool in the fight against cancer 显示文摘 | choenbach K H Nuccitelli R Beebe S J | 2006 | IEEESpectrum2006，43，8： | 1 |
| 4 | A role for endogenous electric fields in wound healing显示文摘 | Nuccitelli R | 2003 | Curt Top Dev Biol2003，58，1： | 1 |
| 5 | Cyclic AMP-dependent protein kinase A plays a role in the directed migration of human keratinocytes in a DC electric field 显示文摘 | Pullar C E lsseroff R R Nuccitelli R | 2001 | Cell Motil Cytoskeleton2001，50，4： | 1 |
| 6 | Zap显示文摘 | SCHOENBACH K H NUCCITELLI R BEEBE S J | 2006 | IEEE Spectrum2006，43，8： | 1 |
| 7 | Nanosecond pulsed electric fields cause melanomas to self-destruct显示文摘 | NUCCITELLI R PLIQUETT U CHEN X | 2006 | Biochem Biophys Res Commun2006，343，2： | 1 |
| 8 | Nanosecond pulsed electric fields cause melanomas to self- destruct显示文摘 | Nuccitelli RL Pliquett U Chen X | 2006 | Biochemical and Biophysical Research Communications2006，343，： | 1 |
| 9 | First-in-human trial of nanoelectroablation therapy for basal cell carcinoma: proof of method显示文摘 | NUCCITELLI R WOOD R KREIS M | 2014 | Exp Dermatol2014，23，2： | 1 |
| 10 | A practical guide to the preparation of Ca2+ buffers显示文摘 | BERS D M PATTON C W NUCCITELLI R | | 0，，： | 1 |
| 11 | Nanosecond pulsed electric fields cause melanomas to self-destruct显示文摘 | Nuccitelli R Pliquett U Chen Xin-hua | 2006 | Biochem Biophys Res Commun2006，343，2： | 1 |
| 12 | Zap 显示文摘 | SCHOENBACH K H NUCCITELLI R BEEBE S J | 2006 | IEEE Spectrum2006，43，8： | 1 |
| 13 | Nanosecond pulsed electric fields cause melanomas to self-destruct显示文摘 | NUCCITELLI R PLIQUETT U CHEN Xinhua | | 0，，02： | 1 |
| 14 | Voltage-clamp study of the activation currents and fast block to polyspermy in the egg of Xenopus laevis Develop显示文摘 | David Glahn Richard Nuccitelli | 2003 | Growth Differ2003，，45： | 1 |
| 15 | Human keratinocytes migrate to the negative pole in direct current electric fields comparable to those measured in mammalian wounds显示文摘 | Nishimura KY Isseroff RR Nuccitelli R | 1996 | Journal of Cell Science1996，109，： | 1 |
| 16 | nanosecond pulsed electric field stimulation of reactive oxygen species in human pancreatic cancer cells is Ca(2+)-dependent显示文摘 | NUCCITELLI R LUI K KREIS M | 2013 | Biochem Biophys Res Commun2013，435，4： | 1 |
| 17 | Non-invasive measurement of bioelectric currents with a vibrating probe 显示文摘 | Reid B Nuccitelli R Zhao M | 2007 | Nat Protoc2007，2，3： | 1 |
| 18 | Nanosecond pulsed electric field stimulation of reactive oxygen species in human pancreatic cancer cells is Ca(2+)-dependent显示文摘 | Nuccitelli R Lui K Kreis M | 2013 | Biochem Biophys Res Commun2013，435，4： | 1 |
| 19 | ZAP:extreme voltage could be a surprisingly delicate tool in the fight against cancer显示文摘 | Schoenbach K H Nuccitelli R Beebe S J | 2006 | IEEE Spectrum2006，43，8： | 1 |
| 20 | First-in-human trial of nanoelectroablation therapy for basal cell carcinoma : proof of method 显示文摘 | Nuccitelli R Wood R Kreis M | 2014 | Exp Dermatol2014，23，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员