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| 1 | Infiltrative xanthogranulomatous cholecystitis mimicking aggressive gallbladder carcinoma: A diagnostic and therapeutic dilemma显示文摘Xanthogranulomatous cholecystitis(XGC) is an uncommon variant of chronic cholecystitis. The perioperative findings in aggressive cases may be indistinguishable from those of gallbladder or biliary tract carcinomas. Three patients presented mass lesions that infiltrated the hepatic hilum,provoked biliary dilatation and jaundice,and were indicative of malignancy. Surgical excision was performed following oncological principles and included extirpation of the gallbladder,extrahepatic bile duct,and hilar lymph nodes,as well as partial hepatectomy. Postoperative morbidity was minimal. Surgical pathology demonstrated XGC and absence of malignancy in all three cases. All three patients are alive and well after years of follow-up. XGC may have such an aggressive presentation that carcinoma may only be ruled out on surgical pathology. In such cases,the best option may be radical resection following oncological principles performed by expert surgeons,in order that postoperative complications may be minimized if not avoided altogether. | Lucas Souto Nacif Amelia Judith Hessheimer Sonia Rodríguez Gómez Carla Montironi Constantino Fondevila | 2017 | World Journal of Gastroenterology2017，23，48： | 13 |
| 2 | Concordance of non-invasive mechanical and serum tests for liver fibrosis evaluation in chronic hepatitis C显示文摘AIM To determine the sensitivity and specificity of liver stiffness measurement(LSM) and serum markers(SM) for liver fibrosis evaluation in chronic hepatitis C.METHODS Between 2012 and 2014,81 consecutive hepatitis C virus(HCV) patients had METAVIR score from liver biopsy compared with concurrent results from LSM [transient elastography(TE) [FibroS can~/ARFI technology(Virtual Touch~)] and SM [FIB-4/aspartate aminotransferase-toplatelet ratio index(APRI)].The diagnostic performance of these tests was assessed using receiver operating characteristic curves.The optimal cut-off levels of each test were chosen to define fibrosis stages F ≥ 2,F ≥ 3 and F = 4.The Kappa index set the concordance analysis.RESULTS Fifty point six percent were female and the median age was 51 years(30-78).Fifty-six patients(70%) weretreatment-na?ve.The optimal cut-off values for predicting F ≥ 2 stage fibrosis assessed by TE were 6.6 kP a,for acoustic radiation force impulse(ARFI) 1.22 m/s,for APRI 0.75 and for FIB-4 1.47.For F ≥ 3 TE was 8.9 kP a,ARFI was 1.48 m/s,APRI was 0.75,and FIB-4 was 2.For F = 4,TE was 12.2 kP a,ARFI was 1.77 m/s,APRI was 1.46,and FIB-4 was 3.91.The APRI could not distinguish between F2 and F3,P = 0.92.The negative predictive value for F = 4 for TE and ARFI was 100%.Kappa index values for F ≥ 3 METAVIR score for TE,ARFI and FIB-4 were 0.687,0.606 and 0.654,respectively.This demonstrates strong concordance between all three screening methods,and moderate to strong concordance between them and APRI(Kappa index = 0.507).CONCLUSION Given the costs and accessibility of LSM methods,and the similarity with the outcomes of SM,we suggest that FIB-4 as well as TE and ARFI may be useful indicators of the degree of liver fibrosis.This is of particular importance to developing countries. | Denise C Paranaguá-Vezozzo Adriana Andrade Daniel F C Mazo Vinicius Nunes Ana L Guedes Taisa G Ragazzo Renata Moutinho Lucas S Nacif Suzane K Ono Venancio A F Alves Flair J Carrilho | 2017 | World Journal of Hepatology2017，9，8： | 7 |
| 3 | The westward lithospheric drift,its role on the subduction and transform zones surrounding Americas:Andean to cordilleran orogenic types cyclicity显示文摘We investigate the effect of the westerly rotation of the lithosphere on the active margins that surround the Americas and find good correlations between the inferred easterly-directed mantle counterflow and the main structural grain and kinematics of the Andes and Sandwich arc slabs.In the Andes,the subduction zone is shallow and with low dip,because the mantle flow sustains the slab;the subduction hinge converges relative to the upper plate and generates an uplifting doubly verging orogen.The Sandwich Arc is generated by a westerly-directed SAM(South American) plate subduction where the eastward mantle flow is steepening and retreating the subduction zone.In this context,the slab hinge is retreating relative to the upper plate,generating the backarc basin and a low bathymetry single-verging accretionary prism.In Central America,the Caribbean plate presents a more complex scenario:(a) To the East,the Antilles Arc is generated by westerly directed subduction of the SAM plate,where the eastward mantle flow is steepening and retreating the subduction zone.(b) To the West,the Middle America Trench and Arc are generated by the easterly-directed subduction of the Cocos plate,where the shallow subduction caused by eastward mantle flow in its northern segment gradually steepens to the southern segment as it is infered by the preexisting westerly-directed subduction of the Caribbean Plateau.In the frame of the westerly lithospheric flow,the subduction of a divergent active ridge plays the role of introducing a change in the oceanic/continental plate’s convergence angle,such as in NAM(North American)plate with the collision with the Pacific/Farallon active ridge in the Neogene(Cordilleran orogenic type scenario).The easterly mantle drift sustains strong plate coupling along NAM,showing at Juan de Fuca easterly subducting microplate that the subduction hinge advances relative to the upper plate.This lower/upper plate convergence coupling also applies along strike to the neighbor continental strike slip fault systems where subduction was terminated(San Andreas and Queen Charlotte).The lower/upper plate convergence coupling enables the capture of the continental plate ribbons of Baja California and Yakutat terrane by the Pacific oceanic plate,transporting them along the strike slip fault systems as para-autochthonous terranes.This Cordilleran orogenic type scenario,is also recorded in SAM following the collision with the Aluk/Farallon active ridge in the Paleogene,segmenting SAM margin into the eastwardly subducting Tupac Amaru microplate intercalated between the proto-LiquineOfqui and Atacama strike slip fault systems,where subduction was terminated and para-autochthonous terranes transported.In the Neogene,the convergence of Nazca plate with respect to SAM reinstalls subduction and the present Andean orogenic type scenario. | Eugenio Aragon Fernando D'Eramo Marco Cuffaro Carlo Doglioni Eleonora Ficini Lucio Pinotti Silvina Nacif Manuel Demartis Irene Hernando Tomas Fuentes | 2020 | Geoscience Frontiers2020，11，4： | 2 |
| 4 | Myocardial TI and extracellular volume fraction mapping at 3 tesla显示文摘 | Lee JJ Liu S Nacif MS | 2011 | J Cardiovasc Magn Reson2011，13，： | 1 |
| 5 | Agenesis of the right hepatic lobe显示文摘 | Nacif LS Buscariolli YS IAlbucluerque LA | 2012 | Case Report Med2012，，7： | 1 |
| 6 | T1 mapping of the myocardium:intra-individual assessment of the effect of field strength,cardiac cycle and variation by myocardial region显示文摘 | Kawel N Nacif M Zavodni A | 2012 | J Cardiovasc Magn Reson2012，14，： | 1 |
| 7 | Successful liver allograft inflow reconstruction with the right gastroepiploic vein显示文摘Portal vein thrombosis is a common complication in cirrhotic patients. When portal vein thrombectomy is not a suitable option, a large collateral vessel can be used for allograft venous inflow reconstruction. We describe an unusual case of successful portal revascularization using the right gastroepiploic vein. The patient underwent a cadaveric orthotopic liver transplantation with end-to-end anastomosis of the portal vein to the right gastroepiploic vein. Six months after liver transplantation the patient is well with good liver function. The use of the right gastroepiploic vein for allograft venous reconstruction is feasible and safe, with a great advantage of avoiding the need of venous jump graft. | Rafael S Pinheiro Ruy J Cruz Jr Lucas S Nacif Matheus F Vane Luiz AC D'Albuquerque | 2016 | Hepatobiliary & Pancreatic Diseases International2016，15，1： | 1 |
| 8 | Myocardial T1 and extracellular volume fraction mapping at 3 tesla显示文摘 | Lee JJ Liu S Nacif MS | 2011 | J Cardiovasc Magn Reson2011，13，： | 1 |
| 9 | Myocardial T1 and extracellular volume fraction mapping at 3 tesla显示文摘 | Lee JJ Liu S Nacif MS | 2011 | J Cardiovasc Magn Reson2011，13，： | 1 |
| 10 | Diagnostic performance of combined cardiac MRI for detection of coronary artery disease显示文摘 | De Mello RA Nacif MS Dos Santos AA | 2012 | Eur J Radio12012，81，8： | 1 |
| 11 | The best approach for diagnosing primary sclerosing cholangitis显示文摘 | Andraus W Haddad L Nacif LS | 2011 | Clinics (Sao Paulo)2011，66，11： | 1 |
| 12 | Spectral studies of semicarbazones derived from 3-and 4-formylpyridine and 3-and 4-acetylpyridine:Crystal and molecular structure of 3-formylpyridine semicarbazone显示文摘 | Beraldo H Nacif W F West D X | 2001 | Spectrochimica Acta Part A2001，57，： | 1 |
| 13 | Myocardial T1 and extracellular volume fraction mapping at 3 tesla显示文摘 | Lee jj Liu S Nacif MS | 2011 | J Cardiovasc Magn Reson2011，13，： | 1 |
| 14 | Morphological and biochemical Characterization of macrophages activated by carrageenan and lipopolysaccharide in vivo显示文摘 | Nacife VP Soeiro Mde N Gomes RN | 2004 | Cell Struct Funct2004，29，2： | 1 |
| 15 | Ketamine ameliorates depressive-like behaviors and immune alterations in adult rats following maternal deprivation显示文摘 | Reus G Z Nacif M P Abelaira H M | 2015 | Neurosci Letters2015，584，： | 1 |
| 16 | The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance显示文摘 | Noureldin RA Liu S Nacif MS | | 0，，01： | 1 |
| 17 | Myocardial T1 and extracellular volume fraction mapping at 3 tesla显示文摘 | Lee JJ Liu S Nacif MS | 2011 | J Cardiovasc Magn Reson2011，13，： | 1 |
| 18 | Double-chambered left ventricle in an adult:diagnosis by CMRI显示文摘 | Nacif MS Mello RA Lacerda Junior OO | | 0，，： | 1 |
| 19 | Significance of CT scan and color Doppler duplex ultrasound in the assessment of Abernethy malformation显示文摘 | Nacif LS Paranaguá-Vezozzo DC Galv?o FH | 2015 | BMC Med Imaging2015，15，： | 1 |
| 20 | Le{t atrial volume quantification using cardiac MRI in atrial fibrillation comparison of the Simpson's method with biplane area length, ellipse, and three-dimensional methods显示文摘 | Nacif M S Barranhas A D Turkbey E | 2013 | Diagn Interv Radiol2013，19，3： | 1 |
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