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| 1 | Minimally invasive surgical treatment of intrahepatic cholangiocarcinoma:A systematic review显示文摘BACKGROUND Intrahepatic cholangiocarcinoma(ICC)is the second most common primary liver cancer and is characterized by an aggressive behavior and a dismal prognosis.Radical surgical resection represents the only potentially curative treatment.Despite the increasing acceptance of laparoscopic liver resection for surgical treatment of malignant liver diseases,its use for ICC is not commonly performed.In fact,to achieve surgical free margins a major resection and/or vascular and/or biliary reconstructions is often needed,as well as an associated lymph node dissection.AIM To review and summarize the current evidences on the minimally invasive resection of ICC.METHODS A systematic review of the literature based on the criteria predetermined by the investigators was performed from the 1st of January 2009 up to the 1st of January2021 in 4 databases(PubMed,Scopus,Google Scholar,and Cochrane databases).All retrospective and prospective studies reporting on the comparative outcomes of open vs minimally invasive treatment of ICC were included.An evaluation of manuscripts quality was achieved using Methodological Index for Non-Randomized Studies criteria and Newcastle-Ottawa Scale.RESULTS After a systematic search 9 studies fulfilled the inclusion criteria.Among the all 3012 included patients,2450 were operated by an open approach and 562 by a minimally invasive(laparoscopic)approach.Baseline characteristics,tumor characteristics,surgical outcomes and oncological outcomes were collected and analyzed,highlighting values with a statistical significant difference between patients treated with open or laparoscopic approach.Shorter hospital stay and lower intraoperative blood losses were reported by some Authors in minimally invasive surgery,on the contrary,in the open group there was a higher number of lymphadenectomies and a higher percentage of major hepatectomies.CONCLUSION Minimally invasive resection of ICC has some short-term benefits and it is safe and feasible only in selected centers with a high experience in laparoscopic approach for liver surgery.Minimally invasive surgery,actually,was considered mainly in patients with a tumor with a diameter<5 cm,without invasion of main biliary duct or main vessel and no vascular or biliary reconstructions were planned.Further studies are needed to elucidate its impact on long term oncologic outcomes. | Renato Patrone Francesco Izzo Raffaele Palaia Vincenza Granata Guglielmo Nasti Alessandro Ottaiano Gilda Pasta Andrea Belli | 2021 | World Journal of Gastrointestinal Oncology2021，13，12： | 3 |
| 2 | Prognostic and predictive response factors in colorectal cancer patients:Between hope and reality显示文摘Colorectal cancer(CRC) represents one of the most commonly diagnosed cancers worldwide.It is the second leading cause of cancer death in Western Countries.In the last decade the survival of patients with metastatic CRC has improved dramatically.Due to the advent of new drugs(irinotecan and oxaliplatin) and target therapies(i.e.,bevacizumab,cetuximab and panitumab),the median overall survival has risen from about 12 mo in the mid nineties to 30 mo recently.Many questions needing of right collocations and more clearness still exist regarding the prognostic factors and the predictive factors of response to therapy.Despite advances in dosing and scheduling of chemotherapy in both adjuvant and advanced settings,and a greater emphasis on early detection,the outlook still remains poor for most patients.Molecular analyses have shown that the natural history of all CRCs is not the same.Individual patients with same stage tumours may have different long term prognosis and response to therapy.In addition,some prognostic variables are likely to be more important than others.Here we review the role of prognostic factors and predictive factors according to the recently published English literature. | Chiara De Divitiis Guglielmo Nasti Massimo Montano Rossella Fisichella Rosario Vincenzo Iaffaioli Massimiliano Berretta | 2014 | World Journal of Gastroenterology2014，20，41： | 2 |
| 3 | Treament for persistent chronic neuralgia after inguinal hemioplasty显示文摘 | Palumbo P Minicucci A Nasti AG | 2007 | Hernia2007，11，6： | 1 |
| 4 | Increased Vascular Endothelial Growth Factor Expression But Impaired Vascular Endothelial Growth Factor Receptor Signaling in the Myocardium of Type 2 Diabetic Patients With Chronic Coronary Heart Disease显示文摘 | Ferdinando Carlo Sasso Daniele Torella Ornella Carbonara Georgina M. Ellison Michele Torella Michelangelo Scardone Claudio Marra Rodolfo Nasti Raffaele Marfella Domenico Cozzolino Ciro Indolfi Maurizio Cotrufo Roberto Torella Teresa Salvatore | 2005 | Journal of the American College of Cardiology2005，，5： | 1 |
| 5 | Chitosan/TPP and ehitosan/TPP-hyaluronic acid nanoparticles: systematic optimisation of the preparative process and preliminary biological evaluation 显示文摘 | Nasti A Zaki NM de Leonardis P | 2009 | Pharm Res2009，26，8： | 1 |
| 6 | Protective role of Toll-like receptor 4 during the initiation stage of cutaneous chemical carci nogenesis显示文摘 | Yusuf N Nasti TH Long JA | 2008 | Cancer Res2008，68，2： | 1 |
| 7 | Regrowth of two ligneous species as affected by clipping intensity and frequency 显示文摘 | Parissi Z M Nastis A S Parissi Z M | 2005 | Cahiers Options Mediterraneennes2005，，： | 1 |
| 8 | Gram - negative endotoxin lipopo- lysaeeharide induces cardiac hypertrophy: Detrimental role of Na( + ) - Ca(2 + ) exchanger显示文摘 | Magi S Nasti AA Gratteri S | 2015 | European Journal of Pharmacology2015，746，4： | 1 |
| 9 | Modeling farmer participation in agri-environmental nitrate pollution reducing schemes 显示文摘 | EIRINl G?NASTIS S A EVAGELOS P | 2011 | Ecological Economics2011，70，13： | 1 |
| 10 | Treament for persistent chronic neuralgia after inguinal hemioplasty 显示文摘 | Palumbo P Minicucei A Nasti AG | 2007 | Hernia2007，11，6： | 1 |
| 11 | C242T polymorphism in CYBA gene(p22phox) and risk of coronary artery disease in a population of Caucasian Italians显示文摘 | Nasti S Spallarossa P Altieri P et al | 2006 | Dis Markers2006，22，3： | 1 |
| 12 | Current strategies to minimize toxicity of oxaliplatin: selection of pharmacogenomic panel tests显示文摘 | Raffaele Di Francia Raffaella Stefania Siesto Daniela Valente Andrea Del Buono Sergio Pugliese Sabrina Cecere Carla Cavaliere Guglielmo Nasti Gaetano Facchini Massimiliano Berretta | 2013 | Anti-Cancer Drugs2013，，10： | 1 |
| 13 | AIDS-related Kaposi's Sarcoma: evaluation of potential new prognostic factors and assessment of the AIDS Clinical Trial Group Staging System in the Haart Era-the Italian Cooperative Group on AIDS and Tumors and the Italian Cohort of Patients Naive From Antiretrovirals显示文摘 | Nasti G Talamini R Antinori A | 2003 | J Clin Oncol2003，21，15： | 1 |
| 14 | Neoadjuvant FOLFIRI+bevacizumab in patients with resectable liver metastases from colorectal cancer:a phase 2 trial显示文摘 | Nasti G Piccirillo MC Izzo F | 2013 | Br J Cancer2013，108，8： | 1 |
| 15 | Oxaliplapin and Capecitabine (XELOX) Based Chemotherapy in the Treatment of Metastatic Colorectal Cancer: The Right Choice in Elderly Patients显示文摘 | Massimiliano Berretta Giuseppe Aprile Guglielmo Nasti Martina Urbani Alessandra Bearz Stefania Lutrino Luisa Foltran Laura Ferrari Renato Talamini Francesco Fiorica Arben Lleshi Vincenzo Canzonieri Chiara Lestuzzi Eugenio Borsatti Rossella Fisichella Umbe | 2013 | Anti-Cancer Agents in Medicinal Chemistry2013，，9： | 1 |
| 16 | 3D curve matching using splines显示文摘 | E Kishon T nastie H Wolflson | 1991 | J of Robotic Systems1991，8，6： | 1 |
| 17 | Impact of highly active antiretroviral therapy on the presenting features and outcome of patients with acquired immunodeficiency syndrome-related Kaposi sarcoma显示文摘 | Nasti G MarteIlotta F Berretta M | 2003 | Cancer2003，98，11： | 1 |
| 18 | Pre-operative chemo- therapy for colorectal cancer liver rnetastases: an update of re- cent clinical trials 显示文摘 | Nasti G Ottaiano A Berretta M | 2010 | Cancer Chemother Pharmacol2010，66，2： | 1 |
| 19 | Protective role of Toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesis显示文摘 | YUSUF N NASTI T H LONG J A et a1 | 2008 | Cancer Res2008，68，： | 1 |
| 20 | Effects of bilateral ovariectomy and postoperative hormonal replacement therapy with 17beta-estradiol or raloxifene on serum leptin levels显示文摘 | TOMMASELLI G A Di CARLO C NASTI A | 2003 | Menopause2003，10，2： | 1 |
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