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| 1 | PHarmacological and toxico- logical studies of Icterenea herbal formulation of Tamarix pakistanica,prepared by Hamdard aboratories(Waqf) Pa- kistan, in rodents 显示文摘 | NASREEN F NAVAID Z | 1993 | Proc Pakistan Congr Zool1993，，13： | 1 |
| 2 | Pharmacological and toxicological studies d ieterene, a herbal formulation d Tamar/x Pakistanica, prepared by Hamdard Laboratories (Waqf) Pakistan in rodents 显示文摘 | Nasreen F Navaid Z U | 1993 | Proc Pakistan Congr Zool1993，13，： | 1 |
| 3 | Cardiac Biomarkers, Mortality, and Post-Traumatic Stress Disorder in Military Veterans显示文摘 | Yang Xue Pam R. Taub Navaid Iqbal Arrash Fard Bailey Wentworth Laura Redwine Paul Clopton Murray Stein Alan Maisel | 2012 | The American Journal of Cardiology2012，，8： | 1 |
| 4 | Pharmacological and toxicological studies of Icterene, a herbal formulation of Tamarix pakistanica, prepared by Hamdard Laboratories (Waqf) Pakistan, in rodents显示文摘 | NASREEN F NAVAID U Z | 1993 | Proe Pakistan Congr Zool1993，13，： | 1 |
| 5 | Pharmacological and toxicological studies of Icterene, a herbal formulation of Tamarix pakistanica, prepared by Hamdard Laboratories (Waqf) Pakistan, in rodents 显示文摘 | Nasreen F Navaid Z | 1993 | Proc Pakistan Congr Zool1993，13，： | 1 |
| 6 | Primary Results of the HABIT Trial (Heart Failure Assessment With BNP in the Home)显示文摘 | Alan Maisel Denise Barnard Brian Jaski Geir Frivold John Marais Maged Azer Michael I. Miyamoto Dawn Lombardo Damon Kelsay Kelly Borden Navaid Iqbal Pam R. Taub Ken Kupfer Paul Clopton Barry Greenberg | 2013 | Journal of the American College of Cardiology2013，，16： | 1 |
| 7 | Histological Features of Parotid Gland of Albino Rats Exposed to. Smokeless Tobacco显示文摘Smokeless tobacco is very common personal habit of people living in various areas of Asia which is an alarming sign for the development of different oral diseases in such people.The aim of present study was to investigate effects of smokeless tobacco on parotid glands of the Aalbano rats by using various percentages of the smokeless tobacco.The rats were divided into three different groups,control group(A) no smokeless tobacco,experimental group(B) 5%smokeless tobacco and experimental group(C) 10%of smokeless tobacco with different feeds required according parameters.Weekly weight gain and partid gland were analyzed through student P test and histological structures were recorded through HE stain and Retculin stain.The results showed that as compared to control group body,weight of the rats was decreased in groups B and C having smokeless tobacco percentage in the diet.Weight of parotid gland as compared to control group was decreased in groups B and C with diet of smokeless tobacco.Further,histological observation under HE stain showed that parotid gland of group B showed mild narrowing of ductal lumen,collapse of vessels and stromal was also increased,in group C parenchymal tissues with loss of acini found damaged and glandular dystrop and lymphatic infiltration were determined moderate to severe.Meanwhile,reticulin stain showed that vascular collapses were shown because of increasing in stromal glandular atrophy in group C as compared to control group.In conclusion,this study showed that smokeless tobacco caused serious injuries in the tissue level in parotid gland with high percentage of smokeless tobacco which highlight health hazards on its consumption. | Sana Murtaza Khoso Pervez Ahmed Khoso Navaid Qazi Mir Hassan Khoso Ahmed Sultan Jatoi Ubedullah Kaka | 2016 | Journal of Northeast Agricultural University(English Edition)2016，23，3： | 0 |
| 8 | Baseline neutrophil-lymphocyte ratio and platelet-lymphocyte ratio appear predictive of immune treatment related toxicity in hepatocellular carcinoma显示文摘BACKGROUND A well-recognized class effect of immune checkpoint inhibitors(ICI)is immune-related adverse events(IrAEs)ranging from low grade toxicities to life-threatening end organ damage requiring permanent discontinuation of ICI.Deaths are reported in<5%of patients treated with ICI.There are,however,no reliable markers to predict the onset and severity of IrAEs.We tested the association between neutrophil-lymphocyte ratio(NLR)and platelet-lymphocyte ratio(PLR)at baseline with development of clinically significant IrAEs(grade≥2)in hepatocellular carcinoma(HCC)patients treated with ICI.AIM To test the association between NLR and PLR at baseline with development of clinically significant IrAEs(grade≥2)in HCC patients treated with ICI.METHODS Data was extracted from an international database from a consortium of 11 tertiary-care referral centers.NLR=absolute neutrophil count/absolute lymphocyte count(ALC)and PLR=platelet count/ALC.Cutoff of 5 was used for NLR and 300 for PLR based on literature.We also tested the association between RESULTS Data was collected from 361 patients treated between 2016-2020 across the United States(67%),Asia(14%)and Europe(19%).Most patients received Nivolumab(n=255,71%).One hundred sixty-seven(46%)patients developed at least one IrAE,highest grade 1 in 80(48%),grade≥2 in 87(52%)patients.In a univariable regression model PLR>300 was significantly associated with a lower incidence of grade≥2 IrAEs(OR=0.40;P=0.044).Similarly,a trend was observed between NLR>5 and lower incidence of grade≥2 IrAEs(OR=0.58;P=0.097).Multivariate analyses confirmed PLR>300 as an independent predictive marker of grade≥2 IrAEs(OR=0.26;P=0.011),in addition to treatment with programmed cell death ligand 1(PD-1)/cytotoxic T lymphocyte-associated protein-4(OR=2.57;P=0.037)and PD-1/tyrosine kinase inhibitor(OR=3.39;P=0.01)combinations.Antibiotic use was not associated with IrAE incidence(OR=1.02;P=0.954).Patients treated with steroids had a>2-fold higher incidence of grade≥2 IrAEs(OR=2.74;P<0.001),although 74%were prescribed steroids for the treatment of IrAEs.CONCLUSION Given that high baseline NLR and PLR are associated with a decreased incidence of IrAEs,lower baseline NLR and PLR may be predictive biomarkers for the appearance of IrAEs in HCC treated with ICI.This finding is in keeping with several studies in solid tumors that have shown that baseline NLR and PLR appear predictive of IrAEs. | Sirish Dharmapuri UmutÖzbek Hiren Jethra Tomi Jun Thomas U Marron Anwaar Saeed Yi-Hsiang Huang Mahvish Muzaffar Matthias Pinter Lorenz Balcar Claudia Fulgenzi Suneetha Amara Arndt Weinmann Nicola Personeni Bernhard Scheiner Tiziana Pressiani Musharraf Navaid Bertram Bengsch Sonal Paul Uqba Khan Dominik Bettinger Naoshi Nishida Yehia Ibrahim Mohamed Arndt Vogel Anuhya Gampa James Korolewicz Antonella Cammarota Ahmed Kaseb Peter R Galle Anjana Pillai Ying-Hong Wan Alessio Cortellini Masatoshi Kudo Antonio D’Alessio Lorenza Rimassa David James Pinato Celina Ang | 2023 | World Journal of Gastrointestinal Oncology2023，15，11： | 0 |
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