|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of bile acids in colon carcinogenesis显示文摘Bile acids(BAs)are cholesterol derivatives synthesized in the liver and then secreted into the intestine for lipid absorption.There are numerous scientific reports describing BAs,especially secondary BAs,as strong carcinogens or promoters of colon cancers.Firstly,BAs act as strong stimulators of colorectal cancer(CRC)initiation by damaging colonic epithelial cells,and inducing reactive oxygen species production,genomic destabilization,apoptosis resistance,and cancer stem cells-like formation.Consequently,BAs promote CRC progression via multiple mechanisms,including inhibiting apoptosis,enhancing cancer cell proliferation,invasion,and angiogenesis.There are diverse signals involved in the carcinogenesis mechanism of BAs,with a major role of epidermal growth factor receptor,and its down-stream signaling,involving mitogen-activated protein kinase,phosphoinositide 3-kinase/Akt,and nuclear factor kappa-light-chain-enhancer of activated B cells.BAs regulate numerous genes including the human leukocyte antigen class I gene,p53,matrix metalloprotease,urokinase plasminogen activator receptor,Cyclin D1,cyclooxygenase-2,interleukin-8,and miRNAs of CRC cells,leading to CRC promotion.These evidence suggests that targeting BAs is an efficacious strategies for CRC prevention and treatment. | Thi Thinh Nguyen Trong Thuan Ung Nam Ho Kim Young Do Jung | 2018 | World Journal of Clinical Cases2018，6，13： | 10 |
| 2 | Aggregation-induced emission (ALE) dye loaded polymer nanoparticles for gene silencing in pancreatic cancer and their in vitro and in vivo biocompatibility evaluation显示文摘 | Rui Hu Chengbin Yang Yucheng Wang Guimiao Lin Wei Qin Qingling Ouyang Wing-Cheung Law Quoc Toan Nguyen Ho Sup Yoon Xiaomei Wang Ken-Tye Yong Ben Zhong Tang | 2015 | Nano Research2015，8，5： | 4 |
| 3 | Theoretical basis of a beneficial role for vitamin D in viral hepatitis显示文摘Abnormal bone metabolism and dysfunction of the calcium-parathyroid hormone-vitamin D axis have been reported in patients with viral hepatitis. Some studies suggested a relationship between vitamin D and viral hepatitis. Genetic studies have provided an opportunity to identify the proteins that link vitamin D to the pathology of viral hepatitis (i.e., the major histocompatibility complex class Ⅱ molecules, the vitamin D receptor, cytochrome P 450 , the renin-angiotensin system, apolipoprotein E, liver X receptor, toll-like receptor, and the proteins regulated by the Sp1 promoter gene). Vitamin D also exerts its effects on viral hepatitis via non-genomic factors, i.e., matrix metalloproteinase, endothelial vascular growth factor, prostaglandins, cyclooxygenase-2, and oxidative stress. In conclusion, vitamin D could have a beneficial role in viral hepatitis. Calcitriol is best used for viral hepatitis because it is the active form of the vitamin D 3 metabolite. | Khanh vinh quoc Luong Lan Thi Hoàng Nguyen | 2012 | World Journal of Gastroenterology2012，18，38： | 3 |
| 4 | Biomass accumulation of Panax vietnamensis in cell suspension cultures varies with addition of plant growth regulators and organic additives显示文摘Objective: To evaluate the impact of plant growth regulators including kinetin(KN),benzyl adenine and naphthalene acetic acid, yeast extract and casein hydrolyzate on biomass accumulation of Vietnamese ginseng Panax vietnamensis(P. vietnamensis) in cell suspension culture.Methods: Cell suspension cultures were established from friable calluses derived from leaves and petioles of 3-year-old in-vitro P. vietnamensis plants. The cell suspension cultures were grown in Murashige and Skoog basal media supplemented with various concentrations of KN, benzyl adenine, naphthalene acetic acid, and yeast extract and casein hydrolyzate.Results: All tested factors generated an increase in the cell biomass of P. vietnamensis in suspension culture, but the impact of each varies depended on the factor type, concentration, and incubation period. Addition of 2.0 mg/L KN resulted in the largest biomass increase after 24 d,(57.0 ± 0.9) and(3.1 ± 0.1) mg/m L fresh and dry weight, respectively,whereas addition of benzyl adenine or naphthalene acetic acid produced optimum levels of Panax cell biomass at 1.0 and 1.5 mg/L, respectively. Addition of the elicitor yeast extract led to a 1.4–2.4 fold increase in biomass of P. vietnamensis, while addition of casein hydrolyzate enhanced biomass accumulation 1.8–2.6 fold.Conclusions: The addition of each factor causes significant changes in biomass accumulation of P. vietnamensis. The largest biomass accumulation is from cultures grown in MS media containing 2.0 mg/L KN for 24 d. The outcome of the present study provides new insights into the optimal suspension culture conditions for studies on the in vitro cell biomass production of P. vietnamensis. | Tuan Tran Trong Dieu-Hien Truong Hoang Chinh Nguyen Dieu-Thai Tran Huyen-Trang Nguyen Thi Giap Do Dang Ho Nguyen Huu | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，9： | 2 |
| 5 | The Incidence of Primary Antibiotic Resistance of Helicobacter pylori in Vietnam显示文摘 | Tran T. Binh Seiji Shiota Lam T. Nguyen Dung D.Q. Ho Hai H. Hoang Long Ta Dung T. Trinh Toshio Fujioka Yoshio Yamaoka | 2013 | Journal of Clinical Gastroenterology2013，，3： | 2 |
| 6 | Upconversion luminescence of Gd2O3:Er3+and Gd2O3:Er3+/silica nanophosphors fabricated by EDTA combustion method显示文摘Gd2O3:Er^3+nanophosphors were fabricated by the combustion method in presence of Na2 ethylene diamine tetra acetic acid(EDTA-Na2)as fuel at not high temperature(≤350℃)within a very short time of 5 min.The added concentration of Er^3+ions in Gd2O3 matrix was changed from 0.5 mol%to 5.0 mol%.The X-ray diffraction pattern of samples indicates the monoclinic structure of Gd2O3:Er^3+.The morphology and chemical composition analysis of the Gd2O3:Er^3+samples are characterized by a field emission scanning electron microscope(FESEM)and a Fourier-transform infrared spectrometer(FTIR).The photoluminescence(PL),photo luminescence excitation(PLE)and upconversion(UC)at room temperature of the prepared materials with different concentrations of Er^3+were investigated.The PL of Gd2O3:Er^3+nanomaterials are shown in visible at 545,594,623,648,688 nm under excitation at 275 nm.The emission bands from transitions of Er^3+from 2P3/2 to 4F9/2 are observed,UC luminescent spectra of the Gd2O3:Er^3+/silica nanocomposites under 976 nm excitation show the bands at 548 and 670 nm.The influence of excitation power at 980 nm for transitions were measured and calculated.The results indicate that the upconversion process of Gd2O3:Er^3+/silica is two photons absorption mechanism.The low temperature dependence of UC luminescent intensities of the main bands of Gd2O3:Er^3+was investigated towards development of a nanotemperature sensor in the range of 10-300 K. | Le Quoc Minh Tran Kim Anh Nguyen Duy Hung Pham Thi Minh Chau Nguyen Thi Quy Hai Ho Van Tuyen Vu Thi Thai Ha Vu Duc Tu Wieslaw Strek | 2019 | Journal of Rare Earths2019，37，11： | 2 |
| 7 | Cardiomyopathy in becker muscular dystrophy:Overview显示文摘Becker muscular dystrophy(BMD) is an X-linked recessive disorder involving mutations of the dystrophin gene. Cardiac involvement in BMD has been described and cardiomyopathy represents the number one cause of death in these patients. In this paper, the pathophysiology, clinical evaluations and management of cardiomyopathy in patients with BMD will be discussed. | Rady Ho My-Le Nguyen Paul Mather | 2016 | World Journal of Cardiology2016，8，6： | 2 |
| 8 | Reaction mechanism of cobalt with silicon dioxide显示文摘 | Nguyen T Ho H L Kotecki D E | 1996 | J Appl Phys1996，79，2： | 1 |
| 9 | Fourier transform profilome- try(FTP) using an innovative band-pass filter for accurate 3-D surface reconstruction显示文摘 | Chen L C Ho H W Nguyen X L | 2010 | Optics and Lasers in Engineering2010，48，： | 1 |
| 10 | Ecoregional variations of aboveground biomass and stand structure in evergreen broadleaved forests显示文摘Biotic and abiotic factors control aboveground biomass(AGB)and the structure of forest ecosystems.This study analyses the variation of AGB and stand structure of evergreen broadleaved forests among six ecoregions of Vietnam.A data set of 1731-ha plots from 52 locations in undisturbed old-growth forests was developed.The results indicate that basal area and AGB are closely correlated with annual precipitation,but not with annual temperature,evaporation or hours of sunshine.Basal area and AGB are positively correlated with trees>30 cm DBH.Most areas surveyed(52.6%)in these old-growth forests had AGB of 100–200 Mg ha^-1;5.2%had AGB of 400–500 Mg ha^-1,and 0.6%had AGB of>800 Mg ha^-1.Seventy percent of the areas surveyed had stand densities of 300–600 ind.ha^-1,and 64%had basal areas of 20–40 m^2 ha^-1.Precipitation is an important factor influencing the AGB of old-growth,evergreen broadleaved forests in Vietnam.Disturbances causing the loss of large-diameter trees(e.g.,>100 cm DBH)affects AGB but may not seriously affect stand density. | Tran Van Do Mamoru Yamamoto Osamu Kozan Vo Dai Hai Phung Dinh Trung Nguyen Toan Thang Lai Thanh Hai Vu Thanh Nam Trieu Thai Hung Hoang Van Thang Tran Duc Manh Cao Chi Khiem Vu Tien Lam Nguyen Quang Hung Tran Hoang Quy Pham Quang Tuyen Trinh Ngoc Bon Nguyen Thi Thu Phuong Ninh Viet Khuong Nguyen Van Tuan Dang Thi Hai Ha Tran Hai Long Dang Van Thuyet Dang Thinh Trieu Nguyen Van Thinh Tran Anh Hai Duong Quang Trung Nguyen Van Bich Dinh Hai Dang Pham Tien Dung Nguyen Huy Hoang Le Thi Hanh Phan Minh Quang Nguyen Thi Thuy Huong Hoang Thanh Son Nguyen Thanh Son Nguyen Thi Van Anh Nguyen Thi Hoai Anh Pham Dinh Sam Hoang Thi Nhung Hoang Van Thanh Nguyen Huu Thinh Tran Hong Van Ho Trung Luong Bui Kieu Hung | 2020 | Journal of Forestry Research2020，31，5： | 1 |
| 11 | TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3'-kinase/protein kinase B signaling pathway显示文摘 | Nguyen M H Ho J M Beattie B K | | 0，，35： | 1 |
| 12 | Clonidine and dexmedetomidine produce antinociceptive synergy in mouse spinal cord显示文摘 | Fairbanks CA Kitto KF Nguyen HO | 2009 | Anesthesiology2009，110，3： | 1 |
| 13 | Fourier transform profilometry (FTP) using a innovative band-pass filter for accurate 3-D surface reconstruction显示文摘 | CHEN Liang-Chia HO HSUAN-WEI XUAN-LOC NGUYEN | 2009 | Optics and Lasers in Engineering2009，48，2： | 1 |
| 14 | Protein quantification and SDS-PAGE electrophoresis in pseudoexfoliation eyes显示文摘 | Küchle M Ho ST Nguyen NX Hannappel E Naumann GOH | 1994 | Invest Ophthalmol Vis Sci1994，35，： | 1 |
| 15 | HVA1 , a LEA gene from barley confers dehydration tolerance in transgenic rice ( Oryza sativa L.) via cell membrane protection显示文摘 | R Chandra Babu Jingxian Zhang A Blum T.-H David Ho R Wu H.T Nguyen | 2003 | Plant Science2003，，4： | 1 |
| 16 | Fourier transform pro- filometry (FTP) using an innovative band-pass filter for accurate 3-D surface reconstruction 显示文摘 | Chen L C Ho H W Nguyen X L | 2010 | Optics and La- sers in Engineering2010，48，2： | 1 |
| 17 | Adaptation of duck plague virus to chicken embryo fibroblast cell culture for vaccine production:Control of Newcastle disease and duck plague in village poultry显示文摘 | NGUYEN T K NGUYEN V D HO V H | 2004 | ACIAR Proceedings2004，，117： | 1 |
| 18 | A model for studying intervertebral disc degeneratuion with magnetic resonance and a nuceleotome 显示文摘 | Nguyen CM Haughton VM Ho KC | 1989 | Invest Radiol1989，24，： | 1 |
| 19 | Clonidine and dexmedetomidine produce antinociceptive synergy in mouse spinal cord显示文摘 | Fairbanks CA Kitto KF Nguyen HO | 2009 | Anesthesiology2009，110，3： | 1 |
| 20 | Fourier transform pro- filometry (FTP) using an innovative band-pass filter for accurate 3-D surface reconstruction显示文摘 | Chen L C Ho H W Nguyen X L | 2010 | Optics and La- sers in Engineering2010，48，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员