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| 1 | 5-Azacytidine induces changes in electrophysiological properties of human mesenchymal stem cells显示文摘以前,导出髓的干细胞(MSC ) 与不确定的脱氧核糖核酸甲基转移酶禁止者 5-azacytidine 对待的老鼠骨头被报导区分 intocardiomyocytes。现在的学习的目的是在从健康骨髓施主获得的人的单音的原子房间调查类似的区别策略的效率。After1-3 段落,文化为 24 h 暴露于到 6 星期进一步的文化跟随的 5-azacytidine (3 mciroM ) 。药处理没导致 myogenic 标记 MyoD 或心脏的 markersNkx2.5 和 GATA-4 的表示并且没在后续期间产出跳动的房间。在补丁夹钳实验,近似 10-15% 对待,未经治疗的房间展出了 L 类型 Ca (2+) 水流。几乎所有房间表面地出现了修正快速或慢的激活动力学的 K (+) 水流。在与匹配时间的控制相比在 6 星期处理以后加倍的 +60 mV 意味着当前的振幅。对待的房间的 Membranecapacitance 比在在处理以后的 controls2 星期内显著地大并且在 6 个星期以后仍然保持高。为 K (+) 隧道 Kv1.1, Kv1.5, Kv2.1, Kv4.3 和 KCNMA1 并且为 Ca (2+) 隧道 Ca (v) 的 mRNAs 的表示层次 1.2 没被 5-azacytidine 影响。在以前显示出禁止 hMSC 的快速或慢慢地激活的 K (+) 水流的集中的 Treatmentwith 钾隧道块 ers tetraethylammonium 和 clofilium 禁止了这些房间的增长。我们的结果建议尽管有进 cardiomyocytes 的 hMSC 的区别的缺席,有 5-azacytidine 的处理在当前的密度引起了深刻变化。 | Bartosz Balanal Cecilia Nicoletti Ihor Zahanich Eva M Graf Torsten Christ Sabine Boxberger Ursula Ravens | 2006 | Cell Research2006，16，12： | 20 |
| 2 | Wolfgang lindner quinine-versus carbamoylated quinine-based chiral anion exchangers: A comparison regarding enantioselectivity for N-protected amino acids and other chiral acids 显示文摘 | Mandl A Nicoletti L Lammerhofer M | 1999 | J of Chromatogr A1999，858，： | 1 |
| 3 | Corpus callosum signal intensity in patients with bipolar and unipolar disorder显示文摘 | Brambilla P Nicoletti M Sassi RB et aI | 2004 | Journal of Neurology Neurosurgery and Psychiatry2004，75，3： | 1 |
| 4 | Safety and efficacy of the percutaneous radial artery approach for coronary angiography and angioplasty in eldly 显示文摘 | Molinarl G Nicoletti l De Benedictis M | 2005 | J Invasive Cardiol2005，17，12： | 1 |
| 5 | Production and fungi toxic activity of SCH642305, a secondary metabolite of Penicillium canescens显示文摘 | Nicoletti R Looez-Gresa M P Manzo F_ | 2007 | Mycopathologia2007，163，： | 1 |
| 6 | A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry 显示文摘 | Nicoletti I Migliorati G Pagliacci M C | 1991 | J Immunol Methods1991，139，2： | 1 |
| 7 | Nutrition and cancer prevention显示文摘 | Tetè S Nicoletti M Saggini A | | 0，，03： | 1 |
| 8 | An appraisal of intermediate filament expression in adult and developing pancreas:vimentin is expressed in alpha cells of rat and mouse embryos显示文摘 | Di Beila A Regoli M Nicoletti C | 2009 | Histochem Cytochem2009，57，6： | 1 |
| 9 | Association of obesity and type Ⅱ diabetes mellitus as a risk factor for gallstones显示文摘 | Pacchioni M Nicoletti C Caminiti M | 2000 | Dig Dis2000，45，10： | 1 |
| 10 | Fast power cycling test for IGBT modules in traction application显示文摘 | HELD M JACOB P NICOLETTI G | 1999 | Journal of Electronics1999，86，10： | 1 |
| 11 | Synthesis of 2-amino-3- methoxypyrazinc 显示文摘 | Bolta M Angelis FD Nicoletti R | 1979 | J Heteroeylic Chem1979，16，1： | 1 |
| 12 | Metabotropic glutamate receptors:beyond the regulation of synaptic transmission显示文摘 | Nicoletti F Battaglia G Storto M | 2007 | Psychoneuroendocrinology2007，24，： | 1 |
| 13 | Gene expression correlating with response to paclitaxel in ovarian carcinoma xenografts显示文摘 | BANI M R NICOLETTI M I ALKHAROUF N W | 2004 | Mol Cancer Ther2004，3，2： | 1 |
| 14 | A rapid and simple method for measuring thymocyte apoptosis by propidiun iodide staining and flow cytometry显示文摘 | Nicoletti I Milirati G Pagliacci M | 1991 | J Immunol Methods1991，139，2： | 1 |
| 15 | Vitamin D3: a helpful immuno - modulator 显示文摘 | Di Rosa M Malagharnera M Nicoletti F | 2011 | Immunology2011，134，2： | 1 |
| 16 | A rapid and simple method for measuring thymoeyte apoptosis by propidi- am iodide staining and flow cytometry 显示文摘 | Nicoletti I Migliorati G Pagliacci M C | 1991 | J Immunol Meth- ods1991，139，： | 1 |
| 17 | Molecular mecha-nisms involved in NAFLD progression显示文摘 | Malaguarnera M Di Rosa M Nicoletti F | 2009 | J Mol Med2009，87，： | 1 |
| 18 | A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry显示文摘 | Nicoletti I Migliorati G Pagliacci M C | 1991 | J Immunol Methods1991，139，2： | 1 |
| 19 | A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry显示文摘 | Nicoletti I Migliorati G Pagliacci M C | 1991 | J Immunol Methods1991，139，2： | 1 |
| 20 | Hypoxidaceae, me-dicinal uses and the norlignan constituents显示文摘 | Nicoletti M GaleffiC MessanaI etal | 1992 | J Ethnophar- macol1992，36，2： | 1 |
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