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| 1 | 西秦岭花岗岩类地球化学和Pb-Sr-Nd同位素组成对基底性质及其构造属性的限制显示文摘对西秦岭印支期5个花岗岩类岩体进行了岩石主量元素、微量元素和Pb-Sr-Nd同位素地球化学的研究, 据此限定西秦岭的地壳基底性质及其构造属性. 结果表明, 西秦岭花岗岩类总体化学成分偏基性, 岩石主要属于准铝质的高钾-钾玄质系列, A/CNK=0.90~1.05 (绝大多数样品<1.0), K2O/Na2O=1.04~1.86. 它们具有相似的微量元素(包括稀土元素)组成模式, (La/Yb)N= 7.49~ 28.79, Eu*/Eu=0.39~0.76. 在Sr-Nd同位素组成上, 西秦岭花岗岩显示一定程度的不均一性, ISr= 0.70682~0.70845, εNd(t)=-4.85~-9.17, TDM=1.26~1.66 Ga. 西秦岭花岗岩类以高放射成因铅同位素组成为特征, 其初始铅同位素比值为: 206Pb/204Pb=17.996~18.468, 207Pb/204Pb=15.565~15.677, 208Pb/204Pb=38.082~38.587. 根据西秦岭花岗岩类的化学和Sr-Nd同位素组成, 揭示了它们的岩浆源区均来自于地壳中高K(Rb)玄武质岩石的部分熔融, 源区物质形成时代可能在900~1400 Ma之间, 由此反映在西秦岭沉积盖层之下含有大量的中、新元古代的高K (Rb)玄武质岩层. 西秦岭印支期花岗岩类与东秦岭印支期花岗岩类的Pb-Sr-Nd同位素组成对比, 指示西秦岭和东秦岭地壳具有不同的基底组成, 两者的分界线大至位于近南北向的宝成铁路线. 西秦岭花岗岩类Pb-Nd同位素组成特征表明西秦岭地壳基底具有扬子块体的构造属性. | 张宏飞 靳兰兰 张利 Nigel Harris 周炼 胡圣虹 张本仁 | 2005 | 中国科学(D辑)2005，35，10： | 130 |
| 2 | 北喜马拉雅淡色花岗岩地球化学:区域对比、岩石成因及其构造意义显示文摘北喜马拉雅出露一系列片麻岩穹窿,这些穹窿被形成于27.5~10Ma的淡色花岗岩侵入.淡色花岗岩的岩石类型为二云母花岗岩,它们的主量元素组成为SiO2=70.97%~74.54%、K2O+Na2O=6.27%~8.09%、K2O/Na2O=0.91~1.36及A/CNK=1.10~1.33.然而,它们在微量元素组成上呈现出较大的变化:Rb=(41~322)×10-6、Sr=(26~139)×10-6、Ba=(135~594)×10-6、(La/Yb)N=0.97~17.31、Eu/Eu=0.29~0.72.北喜马拉雅淡色花岗岩的主量元素和微量元素组成特征类似于高喜马拉雅中新世的二云母花岗岩,而在Ti、Mg、Ca、Ba含量和Rb/Sr比值上明显不同于高喜马拉雅中新世的电气石-白云母花岗岩.北喜马拉雅淡色花岗岩(87Sr/86Sr)t=0.7344~0.8503(t=10Ma),εNd(10Ma)=-12.5~-19.3,与高喜马拉雅淡色花岗岩无明显差异.在岩石成因上,北喜马拉雅和高喜马拉雅中新世淡色花岗岩均起因于构造减压作用,由此导致白云母发生脱水反应诱发高喜马拉雅结晶岩系的深熔.但北喜马拉雅淡色花岗岩形成的地质背景明显不同于高喜马拉雅淡色花岗岩,前者具有较长的时间跨度,开始形成于喜马拉雅渐新世的地壳增厚期,之后形成于中新世穹窿片麻岩的折返时期,而高喜马拉雅淡色花岗岩与中新世高喜马拉雅结晶岩系的构造挤出作用有关.因此。 | 张宏飞 Nigel Harris Randall Parrish 张利 赵志丹 李德威 | 2005 | 地球科学(中国地质大学学报)2005，30，3： | 65 |
| 3 | 评估大气细颗粒物暴露引起的全球疾病负担的一个综合风险函数显示文摘[背景]评估由于环境空气中细颗粒物(PM2.5)长期暴露引起的疾病负担,需要了解相对风险度(RR)函数的图形和幅度。然而,在世界上很多观察到高PM2.5环境浓度的地方,都缺乏足够的直接证据确定死亡RR函数的图形。[目的]建立可用于全球PM2.5暴露范围内成人死因的RR函数:缺血性心脏病(IHD)、脑血管疾病(脑卒中)、慢性阻塞性肺病(COPD)和肺癌(LC)。建立急性下呼吸道感染(ALRI)发病的RR函数,用于估算〈5岁的儿童中死亡率和健康生活损失年数。[方法]通过整合现有的来自于环境空气污染(AAP)、二手烟草烟雾、家用固体烹饪用燃料和主动吸烟(AS)等研究的RR信息,拟合综合暴露-反应(IER)模型。采用颗粒物质的吸入剂量,通过转化AS暴露来估计全年PM2.5的暴露当量。在估算全球环境PM2.5浓度的基础上,得出各国的人群归因分数(PAFs)。[结果]与以往负担评估中使用的其他7种模型相比,IER模型是一种优越的RR预测方法。在不同国家中,归因于AAP暴露的PAF百分数各不相同,分别为:IHD,2~41;脑卒中,1~43;COPD,〈1~21;LC,〈1~25;ALRI,〈1~38。[结论]我们建立了一种以细颗粒物为基础的RR模型,它通过整合来自不同类型的燃烧所产生颗粒物排放的RR信息,涵盖全球范围的暴露。当获得新的RR信息时,可以对这个模型进行更新。 | Richard T.Burnett C.Arden Pope III Majid Ezzati Casey Olives Stephen S.Lim Sumi Mehta Hwashin H.Shin Gitanjali Singh Bryan Hubbell Michael Brauer H.Ross Anderson Kirk R.Smith John R.Balmes Nigel G.Bruce Haidong Kan Francine Laden Annette Prüss-Ustün Michelle C.Turner Susan M.Gapstur W.Ryan Diver Aaron Cohen 何蓉 张伊人 金泰廙 | 2014 | 环境与职业医学2014，31，11： | 80 |
| 4 | Geochemical and Pb-Sr-Nd isotopic compositions of granitoids from western Qinling belt: Constraints on basement nature and tectonic affinity显示文摘Geochemical and Pb-Sr-Nd isotopic compositions of five Indosinian granitoid intrusions from the western Qinling belt provide insights into basement nature and tectonic affinity. The results show that the western Qinling granitoids incline towards basic in their bulk chemical composition. The granitoids belong to high-K to shoshonitic series with K2O/Na2O=1.04-1.86 and are dominantly metaluminous with A/CNK=0.90-1.05 (most samples have A/CNK of <1.0). They have similar trace elemental compo- sitional patterns. In Sr-Nd isotopic compositions, they display some extent heterogeneity with Isr=0.70682-0.70845, εNd(t)=?4.85 to ?9.17 and TDM=1.26-1.66 Ga. They are characterized by high ra- diogenic Pb isotopic compositions. Their initial Pb isotopic ratios are 206Pb/204Pb=17.996-18.468, 207Pb/204Pb=15.565-15.677 and 208Pb/204Pb=38.082-38.587. Geochemical and Sr-Nd isotopic composi- tions reveal that magma for the granitoids was derived from partial melting of high-K (Rb) basaltic rocks, which might be formed in 900-1400 Ma. It is suggested that a large amount of the Proterozoic high-K (Rb) basaltic rocks, which underlie the Phanerozoic sedimentary cover, constitute the crustal basement of the western Qinling belt. Pb-Sr-Nd isotopic compositional comparison between the east- ern Qinling and the western Qinling Indosinian granitoids indicates that the crustal basement of the western Qinling is distinct from that of the eastern Qinling. The Baoji-Chengdu railway close to south-north orientation can be taken as an approximate boundary between both basements. The Pb-Nd isotopic compositional characteristics of the western Qinling granitoids suggest that the basement of the western Qinling belt has an affinity with the Yangtze block. | Nigel HARRIS | 2007 | Science China Earth Sciences2007，50，2： | 33 |
| 5 | 吕梁山隆升时限与演化过程研究显示文摘对吕梁山地区中-新生代隆升时限及其演化的认识,是恢复鄂尔多斯盆地沉积东界的基础,也是探讨华北克拉通演化和破坏等科学问题的有机组成部分.本文以盆山耦合的研究思路为指导,通过较系统的裂变径迹热年代学采样分析,认为吕梁山地区显生宙的隆升活动主要发生在早白垩世晚期以来,可进一步分为缓慢抬升(120~65 Ma)、加速抬升(65~23 Ma)及强烈抬升(23 Ma以来)3个隆升演化阶段,新生代以来是其最主要的隆升时期.抬升作用在空间上具非均衡性,中、北部抬升早,南部晚.晚新生代以来吕梁山地区的快速隆升作用,与东部相邻断陷的沉降具有成因耦合联系.吕梁山地区晚中生代-新生代以来的隆升演化,可能主要与青藏高原挤压造山作用和太平洋板块俯冲的远程效应有关. | 赵俊峰 刘池洋 Nigel MOUNTNEY 芦建军 曹冀龙 杨瑶 薛锐 | 2015 | 中国科学:地球科学2015，45，10： | 20 |
| 6 | 云南省勐腊县人房蚊虫群落特征研究显示文摘目的 :对云南省西双版纳州勐腊县西北方向人房蚊虫群落特征进行研究并探讨蚊类群落学调查与分析方法。方法 :采用CDC和UV诱蚊灯人房通宵捕蚊 ,对所获得的数据材料进行群落学特征分析。结果 :捕获蚊虫 2亚科5属 9亚属 2 0种 2 861只 ,数据处理分析发现人房蚊虫优势种有迷糊按蚊、三带喙库蚊、微小按蚊、中华按蚊、多斑按蚊、可赫按蚊、侧白伊蚊、吉甫按蚊、伪杂鳞库蚊、棕头库蚊 ,优势度分别为 64 .84、46.75、41.17、40 .16、3 2 .3 7、2 8.19、2 1.90、12 .5 9、12 .5 3、16.19;群落的Shannon -Wienner多样性指数、均匀性指数和优势度集中指数分别为 2 .88、0 .67、0 .1914 ;经 χ2 检验 (P >P0 .0 5)和回归方程分析 (r >0 .3 4) ,综合比较发现 :微小按蚊与多斑按蚊、可赫按蚊、棕头库蚊结合的较好 ,中华按蚊与棕头库蚊、可赫按蚊结合的较好 ,可赫按蚊与棕头库蚊结合的较好。结论 :该人房群落蚊种较丰富 ,群落组成和结构复杂 。 | 周红宁 杜尊伟 肖育江 张再兴 王学忠 Nigel Hill Sarah Pettifor | 2002 | 中国媒介生物学及控制杂志2002，13，3： | 20 |
| 7 | 与蝉花有关的虫草菌生物多样性的研究Ⅱ:重要药用真菌蝉花有性型的发现及命名显示文摘我国重要药用真菌蝉花的分类地位和学名在国内外长期混乱,因其有性型未被发现,长期以来误作为根据巴西标本命名的Isaria (Paecilomyces) cicadae。作者最近在井冈山发现了其有性型,研究了标本及分离物的形态特征及多位点系统发育特征,并与GenBank中相关种类的序列进行了对比,证明I.cicadae是物种复合群,确定蝉花是虫草科虫草属中的新种,使用传统药用真菌蝉花的古老名称将其命名为Cordycepschanhua。蝉花子座淡橙色到淡桔黄色,子囊壳半埋生,475–602×222–319μm,子囊孢子246–360×1.5–1.8μm,分孢子圆筒形,6.4–13.8×2.1–3.1μm。孢梗束淡黄色至淡黄褐色,分生孢子长椭圆形或圆筒形,3.5–10.5×1.5–4.5μm。 | 李增智 栾丰刚 HYWEL-JONES Nigel L 张胜利 陈名君 黄勃 孙长胜 陈祝安 李春如 谭悠久 董建飞 | 2021 | 菌物学报2021，40，1： | 18 |
| 8 | Ruptured hepatocellular carcinoma following chemoembolization:a western experience显示文摘BACKGROUND: Transcatheter arterial chemoembolization (TACE) is a recommended first line therapy for unresectable hepatocellular carcinoma (HCC). Serious complications such as neutropenic sepsis and hepatic decompensation are well known, but rupture of HCC following TACE is a rare and potentially fatal complication. The aim of this study was to identify the incidence of ruptured HCC following TACE and the associated risk factors. METHODS: A retrospective analysis was performed using our liver database with 'chemoembolization', 'ruptured HCC' covering the patients who received chemoembolization from January 1995 to December 2005. There were no exclusions. RESULTS: A total of 294 patients received chemoemboliza- tion in 530 sessions during the 10-year period. Of these, 2 ruptured following treatment (incidence 0.68%). The mean age was 65 years and the interval between the treatment and rupture was 2 and 24 days. The common factors were male sex, large tumor size (range 11-13 cm), and exophytic tumor growth. One patient died 2 days after rupture with hepatic decompensation while the second is alive after a 6-month follow up without tumor recurrence. CONCLUSIONS: Ruptured HCC following TACE is a rare but serious complication. Large tumor size, male sex, and exophytic growth of tumor may be predisposing factors for rupture. | Narendra Battula Parthi Srinivasan Mansoor Madanur Srinivas Prabhu Chava Oliver Priest Mohamed Rela Nigel Heaton | 2007 | Hepatobiliary & Pancreatic Diseases International2007，6，1： | 17 |
| 9 | Prostate cancer: diagnosis and staging显示文摘前列腺癌症代表增加的健康负担。与前列腺特定的抗原(PSA ) 的介绍,过去的 20 年看见了前列腺癌症从与局部地先进的疾病或转移介绍了给在屏蔽之上被发现的一个条件逐渐地移动。更多也对 pre 恶意的损害的病理被知道。诊断依靠 trans 直肠的超声(TRUS ) 从在整个前列腺获得活体检视,但是 TRUS 不为阶段是有用的。为阶段的成像例如磁性的回声成像或计算断层摄影术,仍然与病理学的标本相比有低精确性。当前的技术在识别淋巴节点和多骨的转移也是不精密的。诺模图从 PSA,格利森分数并且帮助确定的临床的分级被开发了在激进的前列腺切除术标本的囊外的扩展的风险。改进临床的阶段形式为病理学的舞台的更多的可靠预言并且为对治疗的反应监视被要求。 | Nigel Borley Mark R. Feneley | 2009 | Asian Journal of Andrology2009，11，1： | 15 |
| 10 | 中国栽培植物野生近缘种及其保护对策显示文摘栽培植物野生近缘种资源是植物遗传资源的重要组成部分,拥有独特的生物学特性,在应对气候变化和保证粮食安全方面具有极大潜力和价值。根据我们的初步调查,我国拥有24,000多种栽培植物野生近缘种,其中大多数能够为栽培植物的品种改良提供支持。迁地保护(如种质库)能够收集和保存丰富的遗传资源,但却无法替代能够包含自然进化信息的原生境保护。我国已经建立了169个栽培植物野生近缘种原生境保护区(点),迫切需要制定国家栽培植物野生近缘种保护策略和行动计划,鉴别国家和地区水平上需要优先保护的物种,以及采取步骤,整合迁地和原生境保护方法,达到保护这些优先物种的目的。本文总结了我国栽培植物野生近缘种及其保护所取得的进展,介绍了国内外在植物遗传资源保护利用方面的成功经验,并提出了我国栽培植物野生近缘种的保护策略:建议首先开展栽培植物野生近缘种资源编目工作,并结合国家和地区的环境与资源状况的国际标准,确定优先保护种类;针对不同种类,采取迁地保护和原生境保护相结合的方法保护栽培植物野生近缘种资源。 | 于燕波 王群亮 Shelagh Kell Nigel Maxted Brian V. Ford-Lloyd 魏伟 康定明 马克平 | 2013 | 生物多样性2013，21，6： | 15 |
| 11 | Selective embolization for bleeding visceral artery pseudoaneurysms in patients with pancreatitis显示文摘BACKGROUND:Pancreatitis is associated with arterial complications in 4%-10%of patients,with untreated mortality approaching 90%.Timely intervention at a specialist center can reduce the mortality to 15%.We present a single institution experience of selective embolization as first line management of bleeding pseudoaneurysms in pancreatitis. METHODS:Sixteen patients with pancreatitis and visceral artery pseudoaneurysms were identified from searches of the records of interventional angiography from January 2000 to June 2007.True visceral artery aneurysms and pseudoaneurysms arising as a result of post-operative pancreatic or biliary leak were excluded from the study. RESULTS:In 50%of the patients,bleeding complicated the initial presentation of pancreatitis.Alcohol was the offending agent in 10 patients,gallstones in 3,trauma,drug-induced and idiopathic pancreatitis in one each.All 16 patients had a contrast CT scan and 15 underwent coeliac axis angiography. The pseudoaneurysms ranging from 0.9 to 9.0 cm affected the splenic artery in 7 patients:hepatic in 3,gastroduodenal and right gastric in 2 each,and left gastric and pancreatico-duodenal in 1 each.One patient developed spontaneous thrombosis of the pseudoaneurysm.Fourteen patients had effective coil embolization of the pseudoaneurysm.One patient needed surgical exclusion of the pseudoaneurysm following difficulty in accessing the coeliac axis radiologically.There were no episodes of re-bleeding and no in-hospital mortality. CONCLUSIONS:Pseudoaneurysms are unrelated to the severity of pancreatitis and major hemorrhage can occur irrespective of their size.Co-existent portal hypertension and sepsis increase the risk of surgery.Angiography and selective coil embolization is a safe and effective way to arrest the hemorrhage. | Harsheet Sethi Praveen Peddu Andreas Prachalias Pauline Kane John Karani Mohamed Rela Nigel Heaton | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，6： | 12 |
| 12 | 与蝉花有关的虫草菌生物多样性的研究Ⅰ:文献考证显示文摘蝉花是我国重要药用真菌,但长期以来其名称特别是学名的使用一直混乱。本文从古代医药典籍记载确认,'蝉花'是历史最久、使用最广的中名,对于其他中名具有优先权。其学名Isariacicadae系Miquel(1838)根据巴西标本命名,但模式标本已失,原描述文字及插图均极其简单,与蝉花形态差异较大。其有性型迄今未发现,曾先后被认为是小蝉草Ophiocordyceps sobolifera和大蝉草Tolypocladium dujiaolongae(=Cordyceps cicadae Shing)。本文根据文献考证澄清了国内外关于小蝉草和大蝉草的误用,分析了长期以来大量日本文献中的命名混乱对我国认知蝉花的影响,并质疑Ⅰ.cicadae在中国及其他地区的分布,提出它是一复合种,因此蝉花的分类地位及学名需要进一步研究。 | 李增智 HYWEL-JONES Nigel Leslie 栾丰刚 张胜利 孙长胜 陈祝安 李春如 谭悠久 董建飞 | 2020 | 菌物学报2020，39，12： | 11 |
| 13 | 云南湄公河流域上游河谷地区疟疾媒介传疟作用研究(英文)显示文摘目的通过观察蚊媒季节消长、嗜血习性、叮咬行为和疟疾子孢子率以研究出它们在云南湄公河上游河谷地带传疟作用的关系。方法村内采取诱蚊灯和人工诱捕方法捕蚊;现场采取显微镜解剖蚊虫的方法观察唾腺子孢子,实验室采用ELISA技术检测蚊虫体内环子孢子蛋白(CSP)。结果村内共捕获16种按蚊。现场显微镜解剖7种按蚊,1 010只经产蚊中,发现了7只唾液腺感染子孢子;ELISA方法检测现场捕回的8种按蚊,5 154只各龄期蚊中,发现11只环子孢子蛋白阳性蚊。微小按蚊、中华按蚊、多斑按蚊子孢子阳性率(包括ELISA环子孢子蛋白阳性和镜检唾腺子孢子感染蚊)分别是0.37%、0.22%、0.32%,昆虫接种率分别估算为9.82、3.97、2.69。这些蚊媒叮咬活动起始于黄昏,并整夜有活动,但微小按蚊夜间活动高峰出现于子夜,中华按蚊和多斑按蚊的高峰则在21:00之前。它们的人血指数都在80%以上。结论以上结果显示微小按蚊、中华按蚊和多斑按蚊是湄公河上游河谷地带的重要传疟媒介。 | 周红宁 张再兴 李春富 吴超 王丕玉 Chris Curtis Nigel Hill | 2005 | 中国寄生虫病防治杂志2005，18，6： | 11 |
| 14 | Natural history of hepatic metastases from colorectal cancer-pathobiological pathways with clinical significance显示文摘Colorectal cancer hepatic metastases represent the final stage of a multi-step biological process.This process starts with a series of mutations in colonic epithelial cells,continues with their detachment from the large intestine,dissemination through the blood and/or lymphatic circulation,attachment to the hepatic sinusoids and interactions with the sinusoidal cells,such as sinusoidal endothelial cells,Kupffer cells,stellate cells and pit cells.The metastatic sequence terminates with colorectal cancer cell invasion,adaptation and colonisation of the hepatic parenchyma.All these events,termed the colorectal cancer invasion-metastasis cascade,include multiple molecular pathways,intercellular interactions and expression of a plethora of chemokines and growth factors,and adhesion molecules,such as the selectins,the integrins or the cadherins,as well as enzymes including matrix metalloproteinases.This review aims to present recent advances that provide insights into these cell-biological events and emphasizes those that may be amenable to therapeutic targeting. | Konstantinos A Paschos Ali W Majeed Nigel C Bird | 2014 | World Journal of Gastroenterology2014，20，14： | 10 |
| 15 | On the mechanical behavior of the human biliary system显示文摘This paper reviews the progress made in understanding the mechanical behaviour of the biliary system. Gallstones and diseases of the biliary tract affect more than 10% of the adult population. The complications of gallstones, i.e. acute pancreatitis and obstructive jandice, can be lethal, and patients with acalculous gallbladder pain often pose diagnostic difficulties and undergo repeated ultrasound scans and oral cholecystograms. Moreover, surgery to remove the gallbladder in these patients, in an attempt to relieve the symptoms, gives variable results. Extensive research has been carried out to understand the physiological and pathological functions of the biliary system, but the mechanism of the pathogenesis of gallstones and pain production still remain poorly understood. It is believed that the mechanical factors play an essential role in the mechanisms of the gallstone formation and biliary diseases. However, despite the extensive literature in clinical studies, only limited work has been carried out to study the biliary system from the mechanical point of view. In this paper, we discuss the state of art knowledge of the fluid dynamics of bile flow in the biliary tract, the solid mechanics of the gallbladder and bile ducts, recent mathematical and numerical modelling of the system, and finally the future challenges in the area. | Xiaoyu Luo Wenguang Li Nigel Bird Swee Boon Chin NA Hill Alan G Johnson | 2007 | World Journal of Gastroenterology2007，13，9： | 9 |
| 16 | 多溴联苯醚对大鼠肝细胞CYP1A2依赖性MROD活性的影响显示文摘采用未成熟SD大鼠肝细胞微粒体为试验材料,以2,3,7,8-四氯-二苯基-并-二哑噁英(2,3,7,8- tetrachlorobenzo-p-dioxin,TCDD)作为参照,利用甲氧基-异酚噁脱甲基酶(methoxyresorufin-O- demethylase,MROD)竞争性抑制动力学和荧光光谱法分析法,测定了5种多溴联苯(polybrominated diphenyl ethers,PBDEs)对7-甲氧基-异酚噁唑脱甲基反应的影响,间接研究了这些PBDEs对CYP1A2 的竞争性抑制作用。结果表明,和TCDD相比,PBDEs对MROD活性的抑制作用较弱,亦即对CYP1A2的 竞争性抑制作用较弱。 | 聂芳红 陈进军 Bunce Nigel | 2005 | 中国农学通报2005，21，12： | 8 |
| 17 | An intelligent system for egg quality classification based on visible-infrared transmittance spectroscopy显示文摘The potential of the visible infrared(Vis–IR)(400–1100 nm)transmittance method to assess the internal quality(freshness)of intact chicken egg during storage at a temperature of 30±7C and 25±4%relative humidity was investigated.Two hundred chicken egg samples were used for measuring freshness and spectra collection during egg storage(up to 25 days).Two correlation models,firstly between Haugh unit(HU)and storage time,and secondly between the yolk coefficient(YC)and storage time,were developed and yielded correlation coefficients(R^2)of 0.86 and 0.96,respectively.These models spanned the period for which egg quality decreased dramatically and are statistically significant(P<0.05).In addition,to reduce the dimensionality of the spectra and extract effective wavelengths,two methods were developed based on principal component analysis(PCA)and a genetic algorithm(GA).The output of PCA and GA were also used comparatively to design an egg quality intelligent system.The result of the analyses indicated that identification ratio of GAwith fast Fourier transform(FFT)preprocessing was superior to other methods,and that the quality classification rates of this method for one-day-old eggs are 100%.This study shows that identification of an egg’s freshness using NIR spectroscopy with GA and artificial neural network(ANN)is reliable. | Saman Abdanan Mehdizadeh Saeid Minaei Nigel H.Hancock Mohamad Amir Karimi Torshizi | 2014 | Information Processing in Agriculture2014，1，2： | 8 |
| 18 | rt-PA应用后MMP-2、MMP-9表达的改变及Neuroserpin的影响显示文摘目的 观察重组组织型纤溶酶原激活剂(rt-PA)对血管再通后基质金属蛋白酶-2(MMP-2)、MMP-9表达的影响以及神经源性丝氨酸蛋白酶抑制剂(neuroserpin,NSP)的干预作用。方法 应用易卒中型肾血管性高血压大鼠复制大脑中动脉缺血模型,缺血3 h后再灌注并静脉注射rt-PA,于预组在应用rt-PA前脑内注射NSP,1天后处死,常规病理检查,并应用免疫组织化学和原位杂交的方法观察MMP-2、MMP-9在脑组织的表达。结果 缺血再灌注后MMP-2、MMP-9表达均升高;应用rt-PA后可见缺血再灌注区有灶性出血及红细胞漏出,同时使MMP-9进一步升高,但对MMP-2影响不大;应用rt-PA的同时使用NSP可以减轻缺血损伤,减少出血的发生,并使升高的MMP-9减少至接近正常水平,但NSP可以使MMP-2表达略有升高。结论 rt-PA溶栓后出血转化的发生可能与MMP-9表达增加有关,溶栓时联合应用NSP可能通过降低rt-PA所致的MMP-9表达上调而减轻溶栓治疗的出血并发症。 | 陈立云 曾进胜 李常新 温红梅 解龙昌 Nigel P.Birch 黄如训 | 2003 | 中国神经精神疾病杂志2003，29，4： | 8 |
| 19 | Microstructure and Mechanical Properties of Cold Metal Transfer Welding Similar and Dissimilar Aluminum Alloys显示文摘Integrating structures made from aluminum alloys in automotive industry requires a large amount of joining. As a consequence, the properties of the joints have a significant influence on the overall performance of the whole structure.Robot cold metal transfer welding is a relatively new joining technique and has been used in this work to join 6082-T4 and5182-O aluminum alloy sheets by using ER5356 and ER4043 filler metals. Microstructure characterization was performed by optical microscopy and energy dispersive X-ray spectroscopy, and the mechanical properties were measured by tensile and hardness tests. A correlation is made between welding variables, mechanical properties and the microstructure of welded joints. Results indicate that robot cold metal transfer welding provides good joint efficiency with high welding speed, good tensile strength, and ductility. Owing to the low heat input of robot cold metal transfer welding process, the heat affected zone microstructure was quite similar to base metals, and weld metal microstructure was the controlling factor of joint efficiency. The best performing were the 5182/5182 joints welded with ER5356 and these had mechanical property coefficients of 100%, 98%, and 85% for yield strength, ultimate tensile strength, and elongation, respectively. | Ahmed Elrefaey Nigel G.Ross | 2015 | Acta Metallurgica Sinica(English Letters)2015，28，6： | 8 |
| 20 | Pseudoaneurysm following laparoscopic cholecystectomy显示文摘BACKGROUND:Laparoscopic cholecystectomy(LC)is the operation of choice for removal of the gallbladder. Unrecognized bile duct injuries present with biliary peritonitis and systemic sepsis.Bile has been shown to cause damage to the vascular wall and therefore delay the healing of injured arteries leading to pseudoaneurysm formation.Failure to deal with bile leak and secondary infection may result in pseudoaneurysm formation. This study was to report the incidence and outcomes of pseudoaneurysm in patients with bile leak following LC referred to our hospital. METHODS:A retrospective analysis of our prospectively maintained liver database using pseudoaneurysm, bile leak and bile duct injury following laparoscopic cholecystectomy from January 2000 to December 2005 was performed. RESULTS:A total of 86 cases were referred with bile duct injury and bile leak following LC and of these,4 patients (4.5%)developed hepatic artery pseudoaneurysm(HAP) presenting with haemobilia in 3 and massive intra- abdominal bleed in 1.Selective visceral angiography confirmed pseudoaneurysm of the right hepatic artery in 2 cases,cystic artery stump in one and an intact but ectatic hepatic artery with surgical clips closely applied to the right hepatic artery at the origin of the cystic artery in the fourth case.Effective hemostasis was achieved in 3 patients with coil embolization and the fourth patient required emergency laparotomy for severe bleeding and hemodynamic instability due to a ruptured right hepatic artery.Of the 3 patients treated with coil embolization, 2 developed late strictures of the common hepatic duct. . (CHD)requiring hepatico-jejunostomy and one developed a stricture of left hepatic duct.All the 4 patients are alive at a median follow up of 17 months(range 1 to 65)with normal liver function tests. CONCLUSIONS:HAP is a rare and potentially life- threatening complication of LC.Biloma and subsequent infection are reported to be associated with pseudoaneurysm formation.Late duct stricture is common either due to unrecognized injury at LC or secondary to ischemia after embolization. | Mansoor Ahmed Madanur Narendra Battula Harsheet Sethi Rahul Deshpande Nigel Heaton Mohamed Rela | 2007 | Hepatobiliary & Pancreatic Diseases International2007，6，3： | 8 |
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