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| 1 | Changing spectrum of Budd-Chiari syndrome in India with special reference to non-surgical treatment显示文摘AIM: To evaluate patterns of obstruction, etiological spectrum and non-surgical treatment in patients with Budd-Chiari syndrome in India.METHODS: Forty-nine consecutive cases of Budd-Chiari syndrome (BCS) were prospectively evaluated. All patients with refractory ascites or deteriorating liver function were, depending on morphology of inferior vena cava (IVC) and/or hepatic vein (HV) obstruction, triaged for radiological intervention, in addition to anticoagulation therapy. Asymptomatic patients, patients with diuretic-responsive ascites and stable liver function, and patients unwilling for surgical intervention were treated symptomatically with anticoagulation.RESULTS: Mean duration of symptoms was 41.5 ± 11.2 (range = 1-240) mo. HV thrombosis (HVT) was present in 29 (59.1%), IVC thrombosis in eight (16.3%), membranous obstruction of IVC in two (4%) and both IVC-HV thrombosis in 10 (20.4%) cases. Of 35 cases tested for hypercoagulability, 27 (77.1%) were positive for one or more hypercoagulable states. Radiological intervention was technically successful in 37/38 (97.3%): IVC stenting in seven (18.9%), IVC balloon angioplasty in two (5.4%), combined IVC-HV stenting in two (5.4%), HV stenting in 11 (29.7%), transjugular intrahepatic portosystemic shunt (TIPS) in 13 (35.1%) and combined TIPS-IVC stenting in two (5.4%). Complications encountered in follow-up: death in five, re-stenosis of the stent in five (17.1%), hepatic encephalopathy in two and hepatocellular carcinoma in one patient. Of nine patients treated medically, two showed complete resolution of HVT.CONCLUSION: In our series, HVT was the predominant cause of BCS. In the last five years with the availability of sophisticated tests for hypercoagulability, etiologies weredefined in 85.7% of cases. Non-surgical management was successful in most cases. | Deepak N Amarapurkar Sundeep J Punamiya Nikhil D Patel | 2008 | World Journal of Gastroenterology2008，14，2： | 9 |
| 2 | Prognostic impact of atrial fibrillation on clinical outcomes of acute coronary syndromes,heart failure and chronic kidney disease显示文摘Atrial fibrillation(AF) is the most common type of sustained arrhythmia,which is now on course to reach epidemic proportions in the elderly population. AF is a commonly encountered comorbidity in patients with cardiac and major non-cardiac diseases. Morbidity and mortality associated with AF makes it a major healthcare burden. The objective of our article is to determine the prognostic impact of AF on acute coronary syndromes,heart failure and chronic kidney disease. Multiple studies have been conducted to determine if AF has an independent role in the overall mortality of such patients. Our review suggests that AF has an independent adverse prognostic impact on the clinical outcomes of acute coronary syndromes,heart failure and chronic kidney disease. | Nileshkumar J Patel Aashay Patel Kanishk Agnihotri Dhaval Pau Samir Patel Badal Thakkar Nikhil Nalluri Deepak Asti Ritesh Kanotra Sabeeda Kadavath Shilpkumar Arora Nilay Patel Achint Patel Azfar Sheikh Neil Patel Apurva O Badheka Abhishek Deshmukh Hakan Paydak Juan Viles-Gonzalez | 2015 | World Journal of Cardiology2015，7，7： | 2 |
| 3 | On cluster validity for the fuzzy C-means model显示文摘 | Nikhil P R Bezdek J C | 1995 | IEEE Transactions on Fuzzy Systems1995，3，3： | 1 |
| 4 | Reduced graphene oxide-silver nanoparticle composite as visible light photocatalyst for degradation of colorless endocrine disruptors 显示文摘 | SUSANTA K B NIKHIL R J | 2014 | Appl Mater Interfaces2014，6，20： | 1 |
| 5 | On cluster validity for the fuzzy C - means model显示文摘 | P R NIKHIL J C BEZDEK | 1995 | IEEE Transactions on Fuzzy Systems1995，3，3： | 1 |
| 6 | Spread identity: A new dynamic address remapping mechanism for anonymity and DDoS defense显示文摘 | Dhananjay P Sherman A T Nikhil J | 2013 | Journal of Computer Security2013，21，2： | 1 |
| 7 | Thyroxine replacement therapy reverses sleep-disordered breathing in patients with primary hypothyroidism显示文摘 | Ashish J Surendra KS Nikhil T | 2006 | Sleep Med2006，7，1： | 1 |
| 8 | A multi-stage neural network aided system for detection of microcalcifications in digitized mammograms显示文摘 | Nikhil R Pal Brojeshwar Bhowmick Sanjaya K Patel Srimanta Pal J Dos | 2008 | Neurocompating2008，71，1315： | 1 |
| 9 | Wet Chemical Synthesis of Silver Nanorods and Nanowiros of Controllable Aspect mtio显示文摘 | Latha Gearheart Catherine J Murphy | 2001 | Chemical Communications2001，1，7： | 1 |
| 10 | Allergic reactions to drugs: involvement of T cells显示文摘 | Werner J Nikhil Y | 2000 | Thorax2000，55，2： | 1 |
| 11 | Cysteine-functionalized polyaspartic acid: a polymer for coating and bioconjugation of nanoparticles and quantum dots 显示文摘 | Nikhil R J Nandanan E Jiang J | 2010 | Langmuir2010，26，9： | 1 |
| 12 | A Fast Hardware Approach for Approximate,Efficient Logarithm and Antilogarithm Computations显示文摘 | Suganth P Nikhil J Sunil P K | 2009 | IEEE TRANSACTIONS ON VERY LARGE SCALE INTEGRATION(VLSI)SYSTEMS2009，17，2： | 1 |
| 13 | On cluster validity for the fuzzy C - means model显示文摘 | Nikhil P R Bezdek J C | 1995 | IEEE Transactions on Fuzzy Systems1995，3，3： | 1 |
| 14 | Wet chemical synthesis of silver nanorods and nanowires of controllable aspect ratio显示文摘 | Nikhil R Jana Latha Gearheart Catherine J Murphy | 2001 | Chemical Communications2001，1，7： | 1 |
| 15 | On cluster validity for the fuzzy C-means model显示文摘 | Nikhil P R Bezdek J C | 1995 | IEEE Transactions on Fuzzy Systerns1995，3，3： | 1 |
| 16 | Buffer al- location tot a class of nonlinear stochastic knapsack problems显示文摘 | MACGREGOR SMITH J NIKHIL CHIKHALE | 1995 | Annals of Operations Research1995，58，5： | 1 |
| 17 | On Cluster Validity for the Fuzzy C- Means Model显示文摘 | Nikhil P R Bezdek J C | 1995 | IEEE Transactions on Fuzzy Systems1995，3，3： | 1 |
| 18 | Wet chemical synthesis of high aspect ratio cylindrical gold nanorods显示文摘 | NIKHIL R J LATHA G CATHERINE J M | 2001 | J Phys Chem B2001，105，： | 1 |
| 19 | Effect of Azithromycin treatment on endothelial function in pa2 tients with coronary artery disease and evidence of Chlamydia pneumoniae infection 显示文摘 | Nikhil P Emmanouil GZ J uan Ck | 2002 | Ci rculstion2002，19，： | 1 |
| 20 | Damping properties of epoxy films with nanoscale fillers显示文摘 | SUHR J W NIKHIL A | 2006 | Journal of Intelligent Material Sys-tems and Structures2006，17，3： | 1 |
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