|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A case of successful management with splenectomy of intractable ascites due to congenital dyserythropoietic anemia type II-induced cirrhosis显示文摘The congenital dyserythropoietic anemias comprise agroup of rare hereditary disorders of erythropoiesis,characterized by ineffective erythropoiesis as thepredominant mechanism of anemia and by characteristicmorphological aberrations of the majority of erythroblastsin the bone marrow.Congenital dyserythropoieticanemia type II is the most frequent type.All types ofcongenital dyserythropoietic anemias distinctly share ahigh incidence of iron loading.Iron accumulation occurseven in untransfused patients and can result in heartfailure and liver cirrhosis.We have reported about apatient who presented with liver cirrhosis and intractableascites caused by congenital dyserythropoietic anemiatype Ⅱ.Her clinical course was further complicatedby the development of autoimmune hemolyticanemia.Splenectomy was eventually performed whichachieved complete resolution of ascites,increase ofhemoglobin concentration and abrogation of transfusionrequirements. | Themistoklis Vassiliadis Vassilia Garipidou Vassilios Perifanis Konstantinos Tziomalos OIga Giouleme Kalliopi Patsiaoura Michalis Avramidis Nikolaos Nikolaidis Sofia Vakalopoulou Ioannis Tsitouridis Antonios Antoniadis Panagiotis Semertzidis Anna Kioumi Evangelos Premetis Nikolaos Eugenidis | 2006 | World Journal of Gastroenterology2006，12，5： | 47 |
| 2 | Performance assessment of simple and modified cycle turboshaft gas turbines显示文摘This paper focuses on investigations encompassing comparative assessment of gasturbine cycle options.More specifically,investigation was caried out of technical performanceof turboshaft engine cycles based on existing simple cycle(SC)and its projected modifiedcycles for civil helicopter application.Technically,thermal efficiency,specific fuel consump-tion,and power output are of paramount importance to the overall performance of gas urbineengines.In course of carrying out this research,turbomatch software established at CranfieldUniversity based on gas turbine theory was applied to conduct simulation of a simple cycle(baseline)two-spool helicopter turboshaft engine model with free power turbine.Similarly,some modified gas urbine cycle configurations incoporating unconventional components,such as engine cycle with low pressure compressor(LPC)zero-staged,recuperated enginecycle,and intercooled/recuperated(ICR)engine cycle,were also simulated.In doing so,designpoint(DP)and off-design point(OD)performances of the engine models were established.Thepercentage changes in performance parameters of the modified cycle engines over the simplecycle were evaluated and it was found that to a large extent,the modified engine cycles withunconventional components exhibit better performances in terms of thermal efficiency andspecific fuel consumption than the traditional simple cycle engine.This research made use ofpublic domain open source references. | Barinyima Nkoi Pericles Pilidis Theoklis Nikolaidis | 2013 | Propulsion and Power Research2013，2，2： | 4 |
| 3 | Elevated plasma von Willebrand factor levels in patients with active ulcerative colitis reflect endothelial perturbation due to systemic inflammation显示文摘AIM: To evaluate the plasma von Willebrand factor (vWF) levels in patients with ulcerative colitis (UC) and to investigate their relationship with disease activity,systemic inflammation and coagulation activation.METHODS: In 46 patients with ulcerative colitis (active in 34 patients), clinical data were gathered and plasma vWF levels, markers of inflammation (ESR, CRP, and fibrinogen) and thrombin generation (TAT, F1+2, and D-dimers) were measured at baseline and after 12 wk of treatment. Plasma vWF levels were also determined in 52 healthy controls (HC). The relationship of plasma vWF levels with disease activity, disease extent, response to therapy, acute-phase reactants (APRs) and coagulation markers (COAGs) was assessed.RESULTS: The mean plasma vWF concentrations were significantly higher in active UC patients (143.38±63.73%) than in HC (100.75±29.65%, P = 0.001)and inactive UC patients (98.92±43.6%, P = 0.031).ESR, CRP and fibrinogen mean levels were significantly higher in active UC patients than in inactive UC patients,whereas there were no significant differences in plasma levels of D-dimers, F1+2, and TAT. UC patients with raised APRs had significantly higher mean plasma vWF levels than those with normal APRs (144.3% vs 96.2%,P = 0.019), regardless of disease activity. Although the mean plasma vWF levels were higher in UC patients with raised COAGs than in those with normal COAGs,irrespective of disease activity, the difference was not significant (141.3% vs 118.2%, P = 0.216). No correlation was noted between plasma vWF levels and disease extent. After 12 wk of treatment, significant decreases of fibrinogen, ESR, F1+2, D-dimers and vWF levels were noted only in UC patients with clinical and endoscopic improvement.CONCLUSION: Our data indicate that increased plasma vWF levels correlate with active ulcerative colitis and increased acute-phase proteins. Elevated plasma vWF levels in ulcerative colitis possibly reflect an acutephase response of the perturbed endothelium due to inflammation. In UC patients, plasma vWF levels may be another useful marker of disease activity or response to therapy. | Petros Zezos Georgia Papaioannou Nikolaos Nikolaidis Themistoclis Vasiliadis Olga Giouleme Nikolaos Evgenidis | 2005 | World Journal of Gastroenterology2005，11，48： | 4 |
| 4 | A combined technique of Kalman filter, artificial neural network and fuzzy logic for gas turbines and signal fault isolation显示文摘The target of this paper is the performance-based diagnostics of a gas turbine for the automated early detection of components malfunctions. The paper proposes a new combination of multiple methodologies for the performance-based diagnostics of single and multiple failures on a two-spool engine. The aim of this technique is to combine the strength of each methodology and provide a high success rate for single and multiple failures with the presence of measurement malfunctions. A combination of KF(Kalman Filter), ANN(Artificial Neural Network) and FL(Fuzzy Logic) is used in this research in order to improve the success rate, to increase the flexibility and the number of failures detected and to combine the strength of multiple methods to have a more robust solution. The Kalman filter has in his strength the measurement noise treatment, the artificial neural network the simulation and prediction of reference and deteriorated performance profile and the fuzzy logic the categorization flexibility, which is used to quantify and classify the failures. In the area of GT(Gas Turbine) diagnostics, the multiple failures in combination with measurement issues and the utilization of multiple methods for a 2-spool industrial gas turbine engine has not been investigated extensively.This paper reports the key contribution of each component of the methodology and brief the results in the quantification and classification success rate. The methodology is tested for constant deterioration and increasing noise and for random deterioration. For the random deterioration and nominal noise of 0.4%, in particular, the quantification success rate is above 92.0%, while the classification success rate is above 95.1%. Moreover, the speed of the data processing(1.7 s/sample)proves the suitability of this methodology for online diagnostics. | Simone TOGNI Theoklis NIKOLAIDIS Suresh SAMPATH | 2021 | Chinese Journal of Aeronautics2021，34，2： | 3 |
| 5 | Advanced optimization of gas turbine aero-engine transient performance using linkage-learning genetic algorithm:PartⅡ,optimization in flight mission and controller gains correlation development显示文摘PartⅠhas illustrated the procedures to apply the Linkage Learning Genetic Algorithm(LLGA)in Gas Turbine Engine(GTE)controller gains tuning and generated the optimization results for runway conditions from idle to takeoff.However,the total pressure and temperature of the engine inlet vary as the changing of altitude and Mach number,which would lead to the variation in fuel flow supply regulation.As a result,the optimized gains in runway might not be suitable for other flight conditions.In order to maintain the optimal control performance,the GTE controller gains should be adjusted according to the flight conditions.This paper extends the application of the LLGA method to other flight conditions and then simulates a complete flight mission with different gains and weather condition configurations.For this purpose,the control parameters in the Simulink model of the GTE controller are first corrected by the weather condition in altitude.Then,a typical flight mission is defined and divided into different flight segments based on the altitude and Mach number configuration.One representative point is selected from each segment as the datum point for optimization process.After this step,the LLGA method is used to find the best gains combinations for different flight conditions and the differences in optimization effects for different flight conditions are analyzed subsequently.The simulation results show that the optimization effect of the control performance of each flight condition is dependent on the value of(θδ)~(1/2)and the optimal K_(pla)in some flight conditions is approximately equal to p hd times of the Kplavalue in sea level standard condition.Finally,the complete flight mission is simulated with different gains and weather condition configurations.The simulation results show that the engine performance has been greatly improved after optimization by LLGA in the transient state and the high altitude conditions.In other steady states,the optimization effect is not very obvious. | Yinfeng LIU Soheil JAFARI Theoklis NIKOLAIDIS | 2021 | Chinese Journal of Aeronautics2021，34，4： | 3 |
| 6 | Reduced-dimensional MPC controller for direct thrust control显示文摘With the development of the aircraft gas turbine engine, a control system should be able to achieve effective thrust control to gain better operability. The main contribution of this paper is to develop a novel direct thrust control approach based on an improved model predictive control method through a strategy that reduces the dimension of control sequence. It can not only achieve normal direct thrust control tasks but also maximize the thrust level within the safe operation boundaries. Only the action of switching the objective functions is required to achieve the switch of these two thrust control modes while there is no modification to the control structure. Besides,a shorter control sequence is defined for multivariable control by updating only one control variable at every simulation time instant. Therefore, the time requirement for the solving process of the optimal control sequence is reduced. The proposed controller is implemented to a twin-spool engine.Simulations are conducted in the wide flight envelope, and results show that the average timeconsumption can be reduced up to 65% in comparison with the standard model predictive control,and the thrust can be increased significantly when maximum thrust mode is implemented by using engine limit margins. | Shuwei PANG Soheil JAFARI Theoklis NIKOLAIDIS Qiuhong LI | 2022 | Chinese Journal of Aeronautics2022，35，4： | 2 |
| 7 | Performance of small-scale aero-derivative industrial gas turbines derived from helicopter engines显示文摘This paper considers comparative assessment of simple and advanced cycle small-scale aero-derivative industrial gas turbines derived from helicopter engines.More particularly,investigation was made of technical performance of the small-scale aero-derivative engine cycles based on existing and projected cycles for applications in industrial power generation,combined heat and power concept,rotating equipment driving,and/or allied processes.The investigation was done by carrying out preliminary design and performance simulation of a simple cycle(baseline)two-spool small-scale aero-derivative turboshaft engine model,and some advanced counterpart aero-derivative configurations.The advanced configurations consist of recuperated and intercooled/recuperated engine cycles of same nominal power rating of 1.567 MW.The baseline model was derived from the conversion of an existing helicopter engine model.In doing so,design point and off-design point performances of the engine models were established.In comparing their performances,it was observed that to a large extent,the advanced engine cycles showed superior performance in terms of thermal efficiency,and specific fuel consumption.In numerical terms,thermal efficiencies of recuperated engine cycle,and intercooled/recuperated engine cycles,over the simple cycle at DP increased by 13.5%,and 14.5%respectively,whereas specific fuel consumption of these cycles over simple cycle at DP decreased by 12.5%,and 13%respectively.This research relied on open access public literature for data. | Barinyima Nkoi Pericles Pilidis Theoklis Nikolaidis | 2013 | Propulsion and Power Research2013，2，4： | 2 |
| 8 | Hyperhomocysteinemia in ulcerative colitis is related to folate levels显示文摘AIM: To study the prevalence and clinical significance of hyperhomocysteinemia (hHcys), an independent factor for arterial and venous thrombosis, in a group of patients with ulcerative colitis (UC).METHODS: Fasting homocysteine (Hcys), folate, and vitamin B12 serum levels were measured in 40 UC patients and 50 healthy controls. Clinical data regarding UC were gathered.RESULTS: Median serum Hcys levels in UC patients were similar to those in controls (12.26 μmol/L vs 12.32 μmol/L), but the prevalence of hHcys was higher in UC patients than in controls (30% vs 10%, P= 0.028). UC significantly increased the risk of hHcys (adjusted odds ratio: 4.125;95% CI: 1.26-13.44). Multivariate regression analysis showed that male sex, folate and vitamin B12 deficiency or lower serum values were significant independent predictors of higher Hcys levels in UC patients (r2 = 0.4; P<0.001).CONCLUSION: hHcys is common in UC patients and it is related to folate and vitamin B12 deficiency or lower serum values. It would be reasonable for patients with UC to receive folate and vitamin B complex supplements as a prophylactic measure. | Petros Zezos Georgia Papaioannou Nikolaos Nikolaidis Themistoclis Vasiliadis Olga Giouleme Nikolaos Evgenidis | 2005 | World Journal of Gastroenterology2005，11，38： | 2 |
| 9 | Long-term Follow-up of Patients With Acute Hypertriglyceridemia-Induced Pancreatitis显示文摘 | Vassilios G. Athyros Olga I. Giouleme Nikolaos L. Nikolaidis Themistoklis V. Vasiliadis Vassilios I. Bouloukos Athanasios G. Kontopoulos Nikolaos P. Eugenidis | 2002 | Journal of Clinical Gastroenterology2002，，4： | 2 |
| 10 | Advanced optimization of gas turbine aero-engine transient performance using linkage-learning genetic algorithm:PartⅠ,building blocks detection and optimization in runway显示文摘This paper proposes a Linkage Learning Genetic Algorithm(LLGA)based on the messy Genetic Algorithm(mGA)to optimize the Min-Max fuel controller performance in Gas Turbine Engine(GTE).For this purpose,a GTE fuel controller Simulink model based on the Min-Max selection strategy is firstly built.Then,the objective function that considers both performance indices(response time and fuel consumption)and penalty items(fluctuation,tracking error,overspeed and acceleration/deceleration)is established to quantify the controller performance.Next,the task to optimize the fuel controller is converted to find the optimization gains combination that could minimize the objective function while satisfying constraints and limitations.In order to reduce the optimization time and to avoid trapping in the local optimums,two kinds of building block detection methods including lower fitness value method and bigger fitness value change method are proposed to determine the most important bits which have more contribution on fitness value of the chromosomes.Then the procedures to apply LLGA in controller gains tuning are specified stepwise and the optimization results in runway condition are depicted subsequently.Finally,the comparison is made between the LLGA and the simple GA in GTE controller optimization to confirm the effectiveness of the proposed approach.The results show that the LLGA method can get better solution than simple GA within the same iterations or optimization time.The extension applications of the LLGA method in other flight conditions and the complete flight mission simulation will be carried out in partⅡ. | Yinfeng LIU Soheil JAFARI Theoklis NIKOLAIDIS | 2021 | Chinese Journal of Aeronautics2021，34，4： | 2 |
| 11 | Analysis and design of the prototype of a steel 1-MW wind turbine tower 显示文摘 | Lavassas I Nikolaidis G Zervas P | 2003 | Engineering Structures2003，25，8： | 1 |
| 12 | Robust image watermarking in the spatial domain显示文摘 | | 1998 | Signal Processing1998，66，3： | 1 |
| 13 | Facial feature extraction and determination of pose 显示文摘 | Athanasios Nikolaidis Ioannis Pitas | 2000 | Pattern Recognition2000，33，11： | 1 |
| 14 | Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure显示文摘 | Sokos Nikolaidis LA Mankad S | 2006 | J Card Fail2006，12，4： | 1 |
| 15 | Applications of chaotic signal processing techniques to multimedia Watermark显示文摘 | NIKOLAIDIS N TSEKERIDOU S NIKOLAIDIS A | 2000 | Proceedings of the IEEE workshop on Nonlinear Dynamics in Electronic Systems Catania Italy May 18 -202000，17，： | 1 |
| 16 | Arsenic removal from geothermal waters with zero-valent iron-effect of temperature, phosphate and nitrate显示文摘 | Tyrovola K Nikolaidis N P Veranis N | 2006 | Water Res2006，40，： | 1 |
| 17 | Morphological identification of two tropical dinoflagellates of the genera Gambierdiscus and Sinophysis in the Mediterranean Sea 显示文摘 | Aligizaki K Nikolaidis G | 2008 | Journal of Biological Research-Thessaloniki2008，9，： | 1 |
| 18 | Video shot detection and con- densed representation a review显示文摘 | Cotsaces C Nikolaidis N Pitas I | 2006 | IEEE Signal Processing Maga- zine2006，23，2： | 1 |
| 19 | Eco- nomic evaluation of energy saving measures in a common type of Greek building 显示文摘 | NIKOLAIDIS Y PILAVACHI P A CHLETSIS A | 2009 | Applied Energy2009，86，12： | 1 |
| 20 | Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion显示文摘 | Nikolaidis LA Mankad S Sokos GG | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员