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| 1 | Arbuscular mycorrhizal fungal colonization of Glycyrrhiza glabra roots enhances plant biomass,phosphorus uptake and concentration of root secondary metabolites显示文摘Arbuscular mycorrhizal(AM)fungi penetrate the cortical cells of the roots of vascular plants,and are widely distributed in soil.The formation of these symbiotic bodies accelerates the absorption and utilization of mineral elements,enhances plant resistance to stress,boosts the growth of plants,and increases the survival rate of transplanted seedlings.We studied the effects of various arbuscular mycorrhizae fungi on the growth and development of licorice(Glycyrrhiza glabra).Several species of AM,such as Glomus mosseae,Glomus intraradices,and a mixture of fungi(G.mosseae,G.intraradices,G.cladoideum,G.microagregatum,G.caledonium and G.etunicatum)were used in our study.Licorice growth rates were determined by measuring the colonization rate of the plants by the fungi,plant dry biomass,phosphorus concentration and concentration of secondary metabolites.We established two cloned strains of licorice,clone 3(C3)and clone 6(C6)to exclude the effect of genotypic variations.Our results showed that the AM fungi could in fact increase the leaf and root biomass,as well as the phosphorus concentration in each clone.Furthermore,AM fungi significantly increased the yield of certain secondary metabolites in clone 3.Our study clearly demonstrated that AM fungi play an important role in the enhancement of growth and development of licorice plants.There was also a significant improvement in the secondary metabolite content and yield of medicinal compounds from the roots. | HongLing LIU Yong TAN Monika NELL Karin ZITTER-EGLSEER Chris WAWSCRAH Brigitte KOPP ShaoMing WANG Johannes NOVAK | 2014 | Journal of Arid Land2014，6，2： | 13 |
| 2 | Feedstock choice,pyrolysis temperature and type influence biochar characteristics:a comprehensive meta-data analysis review显示文摘Various studies have established that feedstock choice,pyrolysis temperature,and pyrolysis type influence final biochar physicochemical characteristics.However,overarching analyses of pre-biochar creation choices and correlations to biochar characteristics are severely lacking.Thus,the objective of this work was to help researchers,biochar-stakeholders,and practitioners make more well-informed choices in terms of how these three major parameters influence the final biochar product.Utilizing approximately 5400 peer-reviewed journal articles and over 50,800 individual data points,herein we elucidate the selections that influence final biochar physical and chemical properties,total nutrient content,and perhaps more importantly tools one can use to predict biochar’s nutrient availability.Based on the large dataset collected,it appears that pyrolysis type(fast or slow)plays a minor role in biochar physico-(inorganic)chemical characteristics;few differences were evident between production styles.Pyrolysis temperature,however,affects biochar’s longevity,with pyrolysis temperatures>500℃ generally leading to longer-term(i.e.,>1000 years)half-lives.Greater pyrolysis temperatures also led to biochars containing greater overall C and specific surface area(SSA),which could promote soil physico-chemical improvements.However,based on the collected data,it appears that feedstock selection has the largest influence on biochar properties.Specific surface area is greatest in wood-based biochars,which in combination with pyrolysis temperature could likely promote greater changes in soil physical characteristics over other feedstock-based biochars.Crop-and other grass-based biochars appear to have cation exchange capacities greater than other biochars,which in combination with pyrolysis temperature could potentially lead to longer-term changes in soil nutrient retention.The collected data also suggest that one can reasonably predict the availability of various biochar nutrients(e.g.,N,P,K,Ca,Mg,Fe,and Cu)based on feedstock choice and total nutrient content.Results can be used to create designer biochars to help solve environmental issues and supply a variety of plant-available nutrients for crop growth. | James A.Ippolito Liqiang Cui Claudia Kammann Nicole Wrage‑Mönnig Jose MEstavillo Teresa Fuertes‑Mendizabal Maria Luz Cayuela Gilbert Sigua Jeff Novak Kurt Spokas Nils Borchard | 2020 | Biochar2020，2，4： | 13 |
| 3 | Expression of von Hippel-Lindau tumor suppressor and tumor-associated carbonic anhydrases IX and XII in normal and neoplastic colorectal mucosa显示文摘AIM: To analyze possible relationships between CA ⅠⅩ/CA Ⅻ and pVHL expression in normal and neoplastic colorectal mucosa.METHODS: Immunohistochemical staining of 42 tissue specimens obtained from 17 cancer patients was performed to evaluate the distribution and semi-quantitatively assess the levels of CA ⅠⅩ, CA Ⅻ and pVHL. VHL mRNAs from 14 fresh-frozen tumors was amplified by RT-PCR and subjected to sequencing. CA9 and CA12 mRNA levels were analyzed by semi-quantitative RT-PCR in comparison with VEGFas an indicator of hypoxia that uncouples the pVHL control.RESULTS: Tumor tissues were associated with a borderline increase of CA ⅠⅩ staining signal and slight but significant decrease of CA Ⅻ immunoreactivity, whereas no association was found for pVHL. Sequence analysis of RT-PCR-amplified VHL mRNAs revealed no deletions/mutations, suggesting that they were VHL-competent. We did not observe any correlation between pVHL and CA ⅠⅩ/CA Ⅻ proteins as well as between VEGF and CA9 mRNAs, but the tumor-associated changes in mRNA levels of VEGF and CA12 showed a significant inverse relationship.CONCLUSION: Our results indicate that CA9 and CA12 are regulated by different intratumoral factors and that lack of apparent relationship between the levels of CA ⅠⅩ/CA Ⅻ and pVHL cannot be fully assigned to uncoupling of negative regulatory function of pVHL by tumor hypoxia signified by induced VEGF transcription. The interplay between the functional pVHL and CA ⅠⅩ/CA Ⅻ in colorectal tumors seems rather complex and is not evident merely at the expression levels. | Antti J. Kivela Seppo Parkkila Juha Saarnio Tuomo J. Karttunen Jyrki Kivela Anna-Kaisa Parkkila Maria Bartosova Vojtech Mucha Michal Novak Abdul Waheed William S. Sly Hannu Rajaniemi Silvia Pastorekova Jaromir Pastorek | 2005 | World Journal of Gastroenterology2005，11，17： | 10 |
| 4 | 水平荷载作用下群桩动力特性的研究显示文摘本文采用动力相互作用因子法,对群桩在水平方向谐和激振力作用下的动力反应进行了分析,并与足尺原型桩的野外试验结果进行了比较。由群桩的振幅,刚度和阻尼的频率响应曲线,给出桩-土-桩相互作用对群桩动力特性的影响。边界层概念的引入及由试验确定自由桩长,使理论计算曲线与原型桩的实测结果符合一致。本文还对同一试验场地相同条件下的单桩进行了动力反应对比分析。 | 韩英才 M Novak | 1992 | 土木工程学报1992，25，5： | 10 |
| 5 | Mitochondrial metabolism in regulating macrophage polarization:an emerging regulator of metabolic inflammatory diseases显示文摘As a major type of immune cells with heterogeneity and plasticity,macrophages are classically divided into inflammatory(M1)and alternative/anti-inflammatory(M2)types and play a crucial role in the progress of the inflammatory diseases.Recent studies have shown that metabolism is an importa nt determ inant of macrophage phe no type.Mitoch on dria,one of the most importa nt compartments involving cell metabolism,are closely associated with the regulation of cell functions.In most types of cell,mitochondrial oxidative phosphorylation(OXPHOS)is the primary mode of cellular energy production.However,mitochondrial OXPHOS is inhibited in activated M1 macrophages,ren deri ng them un able to be converted into M2 phe no type.Thus,mitochondrial metabolism is a crucial regulator in macrophage functions.This review summarizes the roles of mitochondria in macrophage polarization and analyzes the molecular mechanisms underlying mitochondrial metabolism and function,which may provide new approaches for the treatment of metabolic inflammatory diseases. | Jina Qing Zizhen Zhang Petr Novak Guojun Zhao Kai Yin | 2020 | Acta Biochimica et Biophysica Sinica2020，52，9： | 5 |
| 6 | A Molecular Framework for the Control of Adventitious Rooting by TIR1/AFB2-Aux/IAADependent Auxin Signaling in Arabidopsis显示文摘In Arabidopsis thaliana,canonical auxin-dependent gene regulation is mediated by 23 transcription factors from the AUXIN RESPONSE FACTOR(ARF)family that interact with auxin/indole acetic acid repressors(Aux/IAAs),which themselves form co-receptor complexes with one of six TRANSPORT INHIBITOR*!/AUXIN-SIGNALLING F-BOX(TIR1/AFB)proteins.Different combinations of co-receptors drive specific sensing outputs,allowing auxin to control a myriad of processes.ARF6 and ARF8 are positive regulators of adventitious root initiation upstream of jasmonate,but the exact auxin co-receptor complexes controlling the transcriptional activity of these proteins has remained unknown.Here,using loss-of-function mutants we show that three Aux/IAA genes,IAA6,IAA9,and IAA17,act additively in the control of adventitious root(AR)initiation.These three IAA proteins interact with ARF6 and/or ARF8 and likely repress their activity in AR development.We show that TIR1 and AFB2 are positive regulators of AR formation and TIR1 plays a dual role in the control of jasmonic acid(JA)biosynthesis and conjugation,as several JA biosynthesis genes are up-regulated in the tir1-1 mutant.These results lead us to propose that in the presence of auxin,TIR1 and AFB2 form specific sensing complexes with IAA6,IAA9,and/or IAA17 to modulate JA homeostasis and control AR initiation. | Abdellah Lakehal Salma Chaabouni Emilie Cavel Rozenn Le Hir Alok Ranjan Zahra Raneshan Ondrej Novak Daniel IPacurar Irene Perrone Frangois Jobert Laurent Gutierrez Laszlo Bako Catherine Bellini | 2019 | Molecular Plant2019，12，11： | 5 |
| 7 | 法国里尔污水厂Actiflo~ Turbo工艺处理大流量暴雨水显示文摘Actiflo~ Turbo工艺是在原Actiflo~微砂加重絮凝高效沉淀工艺的基础上改进更新的,具有抗冲击负荷能力强、快速启动、SS去除率高、运行灵活、占地面积小等特点。介绍了工艺原理、核心设备、工艺特点和适用性。该工艺实际应用于法国里尔市Marquette-Lez-Lille污水厂大流量暴雨水处理,出水指标达到设计要求,可用于湿地灌溉。 | 王银爽 周立 王英 陈晓华 Sylvie Novak | 2017 | 中国给水排水2017，33，22： | 4 |
| 8 | Endogenous Hypoxia in Lateral Root Primordia Controls Root Architecture by Antagonizing Auxin Signaling in Arabidopsis显示文摘As non-photosynthesizing organs, roots are dependent on diffusion of oxygen from the external environment and, in some in stances, from the shoot for their aerobic metabolism . Establishment of hypoxic niches in the developing tissues of plants has been postulated as a consequence of insufficient diffusion of oxygen to satisfy the demands throughout development. Here, we report that such niches are established at specific stages of lateral root primordia development in Arabidopsis thaliana grown under aerobic conditions. Using gain- and loss-of-function mutants, we show that ERF-Ⅶ transcription factors, which mediate hypoxic responses, control root architecture by acting in cells with a high level of auxin signaling. ERF-Ⅶs repress the expression of the auxin-induced genes LBD16, LBD18, and PUCHI, which are essential for lateral root development, by binding to their promoters. Our results support a model in which the establishment of hypoxic n iches in the developing lateral root primordia con tributes to the shutting down of key auxin-induced genes and regulates the production of lateral roots. | Vinay Shukla Lara Lombardi Sergio lacopino Ales Pencik Ondrej Novak Pierdomenico Perata Beatrice Giuntoli Francesco Licausi | 2019 | Molecular Plant2019，12，4： | 4 |
| 9 | Impact of Biochar Amendment on Fertility of a Southeastern Coastal Plain Soil显示文摘 | Jeffrey M. Novak Warren J. Busscher David L. Laird Mohamed Ahmedna Don W. Watts Mohamed A. S. Niandou | 2009 | Soil Science2009，，2： | 3 |
| 10 | Measuring the Customer Experience in Online Environments: A Structural Modeling Approach显示文摘 | Thomas P. Novak Donna L. Hoffman Yiu-Fai Yung | 2000 | Marketing Science2000，，1： | 3 |
| 11 | Influence of Pecan Biochar on Physical Properties of a Norfolk Loamy Sand显示文摘 | Warren J. Busscher Jeff M. Novak Dean E. Evans Don W. Watts M. A. S. Niandou Mohamed Ahmedna | 2010 | Soil Science2010，，1： | 2 |
| 12 | Earthquake response of underground pipelines显示文摘 | A Hindy M Novak | 1979 | Earthquake Engineering and Structural Dynamics1979，7，5： | 2 |
| 13 | Emerging and neglected zoonoses in transplant population显示文摘Zoonoses represent a problem of rising importance in the transplant population.A close relationship and changes between human,animal and environmental health(“One Health”concept)significantly influence the transmission and distribution of zoonotic diseases.The aim of this manuscript is to perform a narrative review of the published literature on emerging and neglected zoonoses in the transplant population.Many reports on donor-derived or naturally acquired(re-)emerging arboviral infections such as dengue,chikungunya,West Nile,tick-borne encephalitis and Zika virus infection have demonstrated atypical or more complicated clinical course in immunocompromised hosts.Hepatitis E virus has emerged as a serious problem after solid organ transplantation(SOT),leading to diverse extrahepatic manifestations and chronic hepatitis with unfavorable outcomes.Some neglected pathogens such as lymphocytic choriomeningitis virus can cause severe infection with multi-organ failure and high mortality.In addition,ehrlichiosis may be more severe with higher casefatality rates in SOT recipients.Some unusual or severe presentations of borreliosis,anaplasmosis and rickettsioses were also reported among transplant patients.Moreover,toxoplasmosis as infectious complication is a well-recognized zoonosis in this population.Although rabies transmission through SOT transplantation has rarely been reported,it has become a notable problem in some countries.Since the spreading trends of zoonoses are likely to continue,the awareness,recognition and treatment of zoonotic infections among transplant professionals should be imperative. | Anna Mrzljak Rafaela Novak Nenad Pandak Irena Tabain Lucija Franusic Ljubo Barbic Maja Bogdanic Vladimir Savic Danko Mikulic Jadranka Pavicic-Saric Vladimir Stevanovic Tatjana Vilibic-Cavlek | 2020 | World Journal of Transplantation2020，10，3： | 2 |
| 14 | Organic matter and polyacrylamide amendment of Norfolk loamy sand显示文摘 | W.J. Busscher J.M. Novak T.C. Caesar-TonThat | 2006 | Soil & Tillage Research2006，，1： | 2 |
| 15 | Vacuole Integrity Maintained by DUF300 Proteins Is Required for Brassinosteroid Signaling Regulation显示文摘Brassinosteroid (BR ) 荷尔蒙发信号在植物生长和开发期间控制多重进程并且和象联系 BRI1 的受体 KINASE1 (BAK1 ) 那样的合作受体通过受体 kinase BRASSINOSTEROID INSENSITIVE1 (BRI1 ) 在血浆膜被开始。BRI1 丰富被 endosomal 再循环并且 vacuolar 指向调整,但是在 BR 受体动力学和 BR 回答的液泡相关的蛋白质的角色留下逃犯。这里,我们证明 BR 发信号的二 DUF300 包含域的 tonoplast 蛋白质, LAZARUS1 (LAZ1 ) 和 LAZ1 HOMOLOG1 (LAZ1H1 ) 的缺席,原因液泡形态学缺点,生长抑制,和组成的激活。有趣地, BAK1 的 tonoplast 累积实质地被增加并且显得有原因地在 laz1 laz1h1 植物连接了到提高的 BRI1 trafficking 和降级。因为无关的液泡异种展出了正常 BR 回答,我们的调查结果显示 DUF300 蛋白质在由维持要求平衡 subcellular BAK1 水池和 BR 受体分发的液泡正直发信号的 BR 的规定起不同作用。 | Qinsong Liu Thomas Vain Corrado Viotti Siamsa M, Doyle Danuse Tarkowska Ondrej Novak Cyril Zipfel Folke Sitbon Stephanie Robert Daniel Hofius | 2018 | Molecular Plant2018，11，4： | 2 |
| 16 | A study of factors that influence zirconia/platinum interfacial impedance using equivalent circuit analysis 显示文摘 | Wang T Novak R F Soltis R E | 2001 | Sens Actuators B Chem2001，77，12： | 2 |
| 17 | Molecular modulation of autophagy: New venture to target resistant cancer stem cells显示文摘Autophagy is a highly regulated catabolic process in which superfluous,damaged organelles and other cytoplasmic constituents are delivered to the lysosome for clearance and the generation of macromolecule substrates during basal or stressed conditions.Autophagy is a bimodal process with a context dependent role in the initiation and the development of cancers.For instance,autophagy provides an adaptive response to cancer stem cells to survive metabolic stresses,by influencing disease propagation via modulation of essential signaling pathways or by promoting resistance to chemotherapeutics.Autophagy has been implicated in a cross talk with apoptosis.Understanding the complex interactions provides an opportunity to improve cancer therapy and the clinical outcome for the cancer patients.In this review,we provide a comprehensive view on the current knowledge on autophagy and its role in cancer cells with a particular focus on cancer stem cell homeostasis. | Harpreet K Mandhair Miroslav Arambasic Urban Novak Ramin Radpour | 2020 | World Journal of Stem Cells2020，12，5： | 2 |
| 18 | Increasing returns and cycles in fishing显示文摘 | Liski M Kort P M Novak A | 2001 | Resources and Energy Economics2001，23，4： | 2 |
| 19 | Vaporsaver杜绝油站油气污染——美国麦迪逊市成功推广OPW油气封存冷凝系统显示文摘 | Bill Novak | 2006 | 中国石油企业2006，，9： | 2 |
| 20 | Soil-Pile interaction in vertical vibration 显示文摘 | Nogami T Novak M | 1976 | Earthquake Eng Struct Dyn1976，4，1： | 2 |
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