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| 1 | Enzymatic synthesis of benzoin in supercritical carbon dioxide显示文摘 | Nuray Celebi a Nuray Yildiz b Ayhan S Demir | 2007 | J Supererit Fluids2007，4，3： | 1 |
| 2 | Dendritic cells from patients with meloma are numerically normal but functionally defective as they fail to upregulate CD80( ( B7 - 1 ) expression by transforming growth factor - batal and interleukin - 10 显示文摘 | Brown R D Pope B Nuray A | 2001 | Blood2001，98，10： | 1 |
| 3 | Effect of pH on chlorophyll degradation and colour loss in blanched green peas显示文摘 | Nuray K Feryal K Hande S B | | 0，，05： | 1 |
| 4 | Automatic performance evaluation of Web search engines 显示文摘 | Can F Nuray R Sevdik A B | 2004 | Information Processing & Management2004，40，3： | 1 |
| 5 | Comparison of transvaginal ultrasonography and saline infusion sonohysterography in evaluating the endometrial cavity in pre- and postmenopausal women with abnormal uterine bleeding 显示文摘 | Mehmet E Ufuk B Nuray B | 2007 | The Journal of The North American Menopause Society2007，155，： | 1 |
| 6 | Correlation of platelet count with seeond-looklaparotomy results and disease progression in patients with advanced epithelial ovarian cancer 显示文摘 | Nuray B Kunter Y Mustafa B | 2004 | Obstet Gynecol2004，103，1： | 1 |
| 7 | Automatic performance evaluation of Web search engines显示文摘 | Can F Nuray R Sevdik A B | 2004 | Information Processing Management2004，，3： | 1 |
| 8 | Characterization of the oil fractions of shale oil obtained by pyrolysis and supercritical water extraction显示文摘 | JALE Y MITHAT Y MEHMET S NURAY O KEITH B BERNARD F | 1995 | 011995，01，： | 1 |
| 9 | Thermal and me-chanical properties of polypropylene nanocomposite materialsreinforced with cellulose nano whiskers 显示文摘 | ELIF B NURAY U AYSEN 0 | 2012 | J Appl PolymSci2012，125，4： | 1 |
| 10 | Automatic performance evaluation of Web search engines 显示文摘 | Can F Nuray R Sevdik A B | 2004 | Information Processing & Management2004，40，3： | 1 |
| 11 | Association between human leukocyte antigen gene polymorphisms and multiple EPIYA-C repeats in gastrointestinal disorders显示文摘BACKGROUND Polymorphisms of human leukocyte antigen(HLA)genes are suggested to increase the risk of gastric cancer(GC).AIM To investigate the HLA allele frequencies of patients with GC relative to a control group in terms of CagA+multiple(≥2)EPIYA-C repeats.METHODS The patient group comprised 94 patients[44 GC and 50 duodenal ulcer(DU)patients],and the control group comprised 86 individuals[(50 non-ulcer dyspepsia patients and 36 people with asymptomatic Helicobacter pylori(H.pylori)].Polymerase chain reaction was performed for the amplification of the H.pylori cagA gene and typing of EPIYA motifs.HLA sequence-specific oligonucleotide(SSO)typing was performed using Lifecodes SSO typing kits(HLA-A,HLA-B HLA-C,HLA-DRB1,and HLA-DQA1-B1 kits).RESULTS The comparison of GC cases in terms of CagA+multiple(≥2)EPIYA-C repeats showed that only the HLA-DQB1*06 allele[odds ratio(OR):0.37,P=0.036]was significantly lower,but significance was lost after correction(Pc=0.1845).The HLA-DQA1*01 allele had a high ratio in GC cases with multiple EPIYA-C repeats,but this was not significant in the univariate analysis.We compared allele frequencies in the DU cases alone and in GC and DU cases together using the same criterion,and none of the HLA alleles were significantly associated with GC or DU.Also,none of the alleles were detected as independent risk factors after the multivariate analysis.On the other hand,in a multivariate logistic regression with no discriminative criterion,HLA-DQA1*01(OR=1.848),HLA-DQB1*06(OR=1.821)and HLA-A*02(OR=1.579)alleles were detected as independent risk factors for GC and DU.CONCLUSION None of the HLA alleles were detected as independent risk factors in terms of CagA+multiple EPIYA-C repeats.However,HLA-DQA1*01,HLA-DQB1*0601,and HLA-A*2 were independent risk factors with no criterion in the multivariate analysis.We suggest that the association of these alleles with gastric malignancies is not specifically related to cagA and multiple EPIYA C repeats. | Suat Saribas Suleyman Demiryas Erkan Yilmaz Omer Uysal Nuray Kepil Mehmet Demirci Reyhan Caliskan Harika Oyku Dinc Seher Akkus Nesrin Gareayaghi Sahra Kirmusaoglu Dogukan Ozbey Hrisi B Tokman Serdar S Koksal Ihsan Tasci Bekir Kocazeybek | 2020 | World Journal of Gastroenterology2020，26，32： | 1 |
| 12 | Automatic Performance Evaluation of Web Search Engines Pages显示文摘 | F Can R Nuray A B Sevdik | 2004 | Information Processing and Management2004，40，3： | 1 |
| 13 | Dendritic cells from patients with meloma are vnumerically normal but functionally defective as they fail to upregulate CD80 (B7-1) expression by transforming growth factor-batal and interleukin- 10显示文摘 | Brown RD Pope B Nuray A | 2001 | Blood2001，98，10： | 1 |
| 14 | Characterization of the oil fractions of shale oil obtained by pyrolysis and supercritical water extraction显示文摘 | JALE Y MITHAT Y MEHMET S NURAY O KEITH B BERNARD F | 1995 | Fuel1995，74，1： | 1 |
| 15 | Dendritic cells from patients with meloma are vnumerically normal but functionally defective as they fail to upregulate CD80((B7-1) expression by transforming growth factor-batal andd interleukin-10显示文摘 | Brown RD Pope B Nuray A | 2001 | Blood2001，98，10： | 1 |
| 16 | Automatic performance evaluation ofWeb search engines 显示文摘 | Can F Nuray R Sevdik A B | 2004 | Information Processing & Management2004，40，3： | 1 |
| 17 | Distribution of transient receptor potential vanilloid-1 channels in gastrointestinal tract of patients with morbid obesity显示文摘BACKGROUND Transient receptor potential vanilloid-1(TRPV1),a nonselective cation channel,is activated by capsaicin,a pungent ingredient of hot pepper.Previous studies have suggested a link between obesity and capsaicin-associated pathways,and activation of TRPV1 may provide an alternative approach for obesity treatment.However,data on the TRPV1 distribution in human gastric mucosa are limited,and the degree of TRPV1 distribution in the gastric and duodenal mucosal cells of obese people in comparison with normal-weight individuals is unknown.AIM To clarify gastric and duodenal mucosal expression of TRPV1 in humans and compare TRPV1 expression in obese and healthy individuals.METHODS Forty-six patients with a body mass index(BMI)of>40 kg/m^(2) and 20 patients with a BMI between 18-25 kg/m^(2) were included.Simultaneous biopsies from the fundus,antrum,and duodenum tissues were obtained from subjects between the ages of 18 and 65 who underwent esophagogastroduodenoscopy.Age,sex,history of alcohol and cigarette consumption,and past medical history regarding chronic diseases and medications were accessed from patient charts and were analyzed accordingly.Evaluation with anti-TRPV1 antibody was performed separately according to cell types in the fundus,antrum,and duodenum tissues using an immunoreactivity score.Data were analyzed using SPSS 17.0.RESULTS TRPV1 expression was higher in the stomach than in the duodenum and was predominantly found in parietal and chief cells of the fundus and mucous and foveolar cells of the antrum.Unlike foveolar cells in the antrum,TRPV1 was relatively low in foveolar cells in the fundus(4.92±0.49 vs 0.48±0.16,P<0.01,Mann-Whitney U test).Additionally,the mucous cells in the duodenum also had low levels of TRPV1 compared to mucous cells in the antrum(1.33±0.31 vs 2.95±0.46,P<0.01,Mann-Whitney U test).TRPV1 expression levels of different cell types in the fundus,antrum,and duodenum tissues of the morbidly obese group were similar to those of the control group.Staining with TRPV1 in fundus chief cells and antrum and duodenum mucous cells was higher in patients aged≥45 years than in patients<45 years(3.03±0.42,4.37±0.76,2.28±0.55 vs 1.9±0.46,1.58±0.44,0.37±0.18,P=0.03,P<0.01,P<0.01,respectively,Mann-Whitney U test).The mean staining levels of TRPV1 in duodenal mucous cells in patients with diabetes and hypertension were higher than those in patients without diabetes and hypertension(diabetes:2.11±0.67 vs 1.02±0.34,P=0.04;hypertension:2.42±0.75 vs 1.02±0.33,P<0.01 Mann-Whitney U test).CONCLUSION The expression of TRPV1 is unchanged in the gastroduodenal mucosa of morbidly obese patients demonstrating that drugs targeting TRPV1 may be effective in these patients. | Unal Atas Nuray Erin Gokhan Tazegul Gulsum Ozlem Elpek Bülent Yıldırım | 2022 | World Journal of Clinical Cases2022，10，1： | 0 |
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