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| 1 | Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: Results of a multicent显示文摘AIM: Anti-Saccharomyces cerevisiae antibodies (ASCA), anti-nuclear associated anti-neutrophil antibodies (NANA) and antibodies to exocrine pancreas (PAB), are serological tools for discriminating Crohn’s disease (CrD) and ulcerative colitis (UC). Like CrD, coeliac disease (CoD) is an inflammatory bowel disease (IBD) associated with (auto) antibodies. Performing a multicenter study we primarily aimed to determine the performance of ASCA, NANA and PAB tests for IBD diagnosis in children and adults, and secondarily to evaluate the prevalence of these markers in CoD. METHODS: Sera of 109 patients with CrD, 78 with UC, 45 with CoD and 50 healthy blood donors were retrospectively included. ASCA, NANA and PAB were detected by indirect immunofluorescence (IIF). RESULTS: ASCA+/NANA- profile displayed a positive predictive value of 94.2% for CrD. Detection of ASCA was correlated with a more severe clinical profile of CrD and treatment of the disease did not influence their serum levels. ASCA positivity was found in 37.9% of active CoD.PAB were found in 36.7% CrD and 13.3% CoD patients and were not correlated with clinical features of CrD, except with an early onset of the disease. Fifteen CrD patients were ASCA negative and PAB positive. CONCLUSION: ASCA and PAB detected by IIF are specific markers for CrD although their presence does not rule out a possible active CoD. The combination of ASCA, NANA and PAB tests improves the sensitivity of immunological markers for CrD. Repeating ASCA, NANA, and PAB testing during the course of CrD has no clinical value. | S Desplat-Jégo C Johanet A Escande J Goetz N Fabien N Olsson E Ballot J Sarles JJ Baudon JC Grimaud M Veyrac P Chamouard RL Humbel | 2007 | World Journal of Gastroenterology2007，13，16： | 24 |
| 2 | Nitrite,a novel method to decrease ischemia/reperfusion injury in the rat liver显示文摘AIM:To investigate whether nitrite administered prior to ischemia/reperfusion(I/R)reduces liver injury.METHODS:Thirty-six male Sprague-Dawley rats were randomized to 3 groups,including sham operated(n=8),45-min segmental ischemia of the left liver lobe(IR,n=14)and ischemia/reperfusion(I/R)preceded by the administration of 480 nmol of nitrite(n=14).Serum transaminases were measured after 4 h of reperfusion.Liver microdialysate(MD)was sampled in 30-min intervals and analyzed for glucose,lactate,pyruvate and glycerol as well as the total nitrite and nitrate(NOx).The NOx was measured in serum.RESULTS:Aspartate aminotransferase(AST)at the end of reperfusion was higher in the IR group than in the nitrite group(40±6.8μkat/L vs 22±2.6μkat/L,P=0.022).Similarly,alanine aminotransferase(ALT)was also higher in the I/R group than in the nitrite group(34±6μkat vs 14±1.5μkat,P=0.0045).The NOx in MD was significantly higher in the nitrite group than in the I/R group(10.1±2.9μmol/L vs 3.2±0.9μmol/L,P=0.031)after the administration of nitrite.During ischemia,the levels decreased in both groups and then increased again during reperfusion.At the end of reperfusion,there was a tendency towards a higher NOx in the I/R group than in the nitrite group(11.6±0.7μmol/L vs 9.2±1.1μmol/L,P=0.067).Lactate in MD was significantly higher in the IR group than in the nitrite group(3.37±0.18 mmol/L vs 2.8±0.12 mmol/L,P=0.01)during ischemia and the first 30 min of reperfusion.During the same period,glycerol was also higher in the IRI group than in the nitrite group(464±38μmol/L vs 367±31μmol/L,P=0.049).With respect to histology,there were more signs of tissue damage in the I/R group than in the nitrite group,and29%of the animals in the I/R group exhibited necrosis compared with none in the nitrite group.Inducible nitric oxide synthase transcription increased between early ischemia(t=15)and the end of reperfusion in both groups.CONCLUSION:Nitrite administered before liver ischemia in the rat liver reduces anaerobic metabolism and cell necrosis,which could be important in the clinical setting. | Bergthor Bjrnsson Linda Bojmar Hans Olsson Tommy Sundqvist Per Sandstrm | 2015 | World Journal of Gastroenterology2015，21，6： | 8 |
| 3 | 参与式管理解决冲突:遥感和GIS用作瑞典北部驯鹿业土地利用需求信息交流的工具显示文摘在解决复杂的土地管理问题时,对短缺或者有争执的资源进行地理评估有助于不同利益相关者之间沟通认识和增进理解。本文中,我们说明如何使用遥感和GIS收集和汇总瑞典北部驯鹿放牧者和其他土地使用者(林业、采矿业、旅游业等等)的土地使用活动及使用模式的信息。该项目主要基于最终的土地使用者,即驯鹿放牧者们所做的工作,体现了面向土地使用者的新的努力。发展驯鹿业的土地利用规划的基础有以下几个方面:收集并数字化传统的驯鹿栖息地生态学和景观信息;将这些信息与来自野外调查及基于人造卫星观测的植被分类结果整合;绘制其他土地使用者的活动情况图。最终的土地利用规划提供的信息有利于驯鹿放牧者与其他利益相关者之间的磋商,并有助于驯鹿管理实施。该项目可作为一种大众参与和计划编制的模式,从而使本土信息和先进的遥感技术融入一个交互式的过程中。 | Per Sandstrm Tina Granqvist Pahlén Lars Edenius Hans Tφmmervik Olle Hagner Leif Hemberg Hkan Olsson Karin Baer Thomas Stenlund Lars Gran Brandt Mikael Egberth 周立志 程利群 | 2003 | AMBIO-人类环境杂志2003，32，8： | 4 |
| 4 | 大堡礁和大峡谷世界遗产区的适应性管理显示文摘关于人类和环境相互关系的传统观念正在迅速改变。那种认为人类与自然是相互隔离的,自然资源是取之不尽用之不竭的,而且认为世界是稳定的、可以预测的并且是平衡的旧观点已经过时了。在动态的社会-生态景观中强调学习和灵活性管理为基础的适应性方法的新的理念框架已经迅速初现端倪。我们以两个典型的世界遗产地区(大堡礁和大峡谷)为案例来研究如何在自然资源管理中通过改善科学和社会两个方面的结合来指导多尺度管理系统的变革从而应对和处理人类越来越占据主导的世界中出现的不确定性、风险和变化。 | Terence P.Hughes Lance H.Gunderson Carl Folke Andrew H.Baird David Bellwood Fikret Berkes Beatrice Crona Ariella Helfgott Heather Leslie Jon Norberg Magnus Nystrm Per Olsson Henrik sterblom Marten Scheffer Heidi Schuttenberg Robert S.Steneck Maria Teng Max Troell Brian Walker James Wilson Boris Worm 丁莉 | 2007 | AMBIO-人类环境杂志2007，36，B11： | 4 |
| 5 | 心房颤动——当今面临的挑战显示文摘在过去数年里,临床和科撞方面对心房颤动(房颤)的关注明显增加,有关这一论题的出版物数量迅速、稳定的增长就是证明。虽然已有一些新方法治疗遮一心律失常一但大多数房颤患者仍然不得不忍受这一心律失常,包括其不良后果和症状,房颤无疑是虽迫切需要有更好治疗方法的一种心律失常。为了达到这一目的,就需要更深刻地认识房颤的机制.以便开发直接影响这一基础病理生理机制的治疗措施。 | Olsson SB Hansson A Hedin E Holm M Ingemansson M Johansson R Meurling C Pehrson S Roijer A Yuan S 方丕华 | 1997 | 中华心律失常学杂志1997，1，1： | 3 |
| 6 | 莺总科鸟类的系统分类进展评述(英文)显示文摘本文评述了莺总科鸟类的系统分类,并重点探讨科间、属内系统发育关系以及种级分类地位。基于已发表的 DNA 序列数据,对马岛莺科(Bernieridae)和柳莺科(Phylloscopidae)重新进行了分析。大量的分子水平的研究让我们对鸟类系统发育的认识有了很大提高。但是,由于一些主要进化分支(科)的快速分化,使得这些科之间的相互关系依然不明确。同样,分子标记和(或)鸣声及其他生活史资料在大量研究中的应用,大大提高了种级水平的分类可靠性。我们推测,随着人们运用现代的整合方法对新类群的不断研究,物种数量会不断增加。 | Per ALSTRM Urban OLSSON 雷富民 | 2013 | Chinese Birds2013，，2： | 3 |
| 7 | Fecal calprotectin one year after ileocaecal resection for Crohn’s disease — A comparison with findings at ileocolonoscopy显示文摘 | Anders Lasson Hans Strid Lena ?hman Stefan Isaksson Mikael Olsson Britt Rydstr?m Kjell-Arne Ung Per-Ove Stotzer | 2013 | Journal of Crohn’s and Colitis2013，，： | 2 |
| 8 | Clinical and aetiological aspects of epilepsy in children with cerebral palsy 显示文摘 | Carlsson M Hagberg G Olsson I | 2003 | Dev Med Child Neurol2003，45，6： | 1 |
| 9 | T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytoponic purpura显示文摘 | Olsson B Andersson PO Jemas M | 2003 | Nat Med2003，9，9： | 1 |
| 10 | Comparing the Schrdinger and spinless Salpeter equation for heavy-quark bound states 显示文摘 | Olsson M G and Suchyta C | 1986 | Phys Rev D1986，33，11： | 1 |
| 11 | Costs of Equity and Earnings Attributes显示文摘 | Lafond R Olsson P M Schipper K | 2004 | The Accounting Review2004，79，4： | 1 |
| 12 | Functional outcome in patients with lacunar infarction显示文摘 | Soderfeldt B Olsson GB | 1996 | Stroke1996，27，5： | 1 |
| 13 | Improving the pathogenicity of a nematode-trapping fungus by genetic engineering of a subtilisin with nematotoxic activity显示文摘 | Ahman J Johansson T Olsson M | 2002 | Appl Environ Microbiol2002，68，： | 1 |
| 14 | Soil seed flora,germination and regeneration pattern of woody species in an acacia woodland of the Rift Valley in Ethiopia显示文摘 | ARGAW M TEKETAY D OLSSON M | 1999 | Journal of Arid Environments1999，43，4： | 1 |
| 15 | The use of prostate specific antigen density to enhance the predictive value of intermediate levels of serum prostate specific antigen显示文摘 | BENSON M C WHANG I S OLSSON C A | 1992 | J Urol1992，147，： | 1 |
| 16 | Fitting phase-type distributions via the EM algorithm 显示文摘 | Asmussen S Nerman O Olsson M | 1996 | Scandinavian Journal of Statis- tics1996，23，4： | 1 |
| 17 | Biochemical markers to predict preeclamp- sia 显示文摘 | Anderson U D Olsson M G Kristensen K H | 2012 | Placenta2012，，： | 1 |
| 18 | T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura显示文摘 | Olsson B Andersson PO Jernis M | 2003 | Nat Med2003，9，： | 1 |
| 19 | Caspases and cancer 显示文摘 | Olsson M Zhivotovsky B | 2011 | Cell Death Differ2011，18，9： | 1 |
| 20 | High efficiency dye sensitized nanocrystalline solar cells based on sputter deposited Ti oxide films显示文摘 | Gomez M M Lu J Olsson E | 2000 | Solar Energy Materials & Solar Cells2000，64，4： | 1 |
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