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| 1 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 2 | Copper transportion of WD protein in hepatocytes from Wilson disease patients in vitro显示文摘AIM: To study the effect of copper transporting P-type ATPase in copper metabolism of hepatocyte and pathogenesis of Wilson disease (WD).METHODS: WD copper transporting properties in some organelles of the cultured hepatocytes were studied from WD patients and normal controls. These cultured hepatocytes were incubated in the media of copper 15mg.L-1 only, copper 15 mg. L-1 with vincristine (agonist of P-type ArPase) 0.5mg. L-1, or copper 15 mg. L-1 withvanadate (antagonist of P-type ATPase) 18.39 mg. L-1separately. Microsome (endoplasmic reticulum and Golgi apparatus), lysosome, mitochondria, and cytosol were isolated by differential centrifugation. Copper contents in these organelles were measured with atomic absorption spectrophotometer, and the influence in copper transportion of these organelles by vanadate and vincristine were comparatively analyzed between WD patients and controls.WD copper transporting P-type ATPase was detected by SDS-PAGE in conjunction with Western blot in liver samples of WD patients and controls.RESULTS: The specific WD proteins (Mr155 000 lanes) were expressed in human hepatocytes, including the control and WD patients. After incubation with medium containing copper for 2 h or 24 h, the microsome copper concentration in WD patients was obviously lower than that of controls,and the addtion of vanadate or vincristine would change the copper transporting of microsomes obviously. When incubated with vincristine, levels of copper in microsome were significantly increased, while incubated with vanadate,the copper concentrations in microsome were obviously decreased. The results indicated that there were Wdproteins, the copper transportion P-type ATPase in the microsome of hepatocytes. WD patients possessed abnormal copper transporting function of WD protein in the microsome, and the agonist might correct the defect of copper transportion by promoting the activity of copper transportion P-type ATPase.CONCLUSION: Copper transportion P-type ATPase plays an important role in hepatocytic copper metabolism.Dysfunction of hepatocytic WD protein copper transportion might be one of the most important factors for WD. | Guo-Qing Hou~1 Xiu-Ling Liang~2 Rong Chen~2 Li-Wen Tang~3 Ying Wang~2 Ping-Yi Xu~2 Ying-Ru Zhang~2 Cui-Hua Ou~2 1 Department of Neurology.Guangzhou First Municipal People’s Hospital,Guangzhou Medical College,Guangzhou 510180,Guangdong Province.China2 Department of Neurology.First Affiliated Hospital.Sun Yat-Sen University of Medical Sciences.Guangzhou 510080.Guangdong Province.China3 Department of Pharmacology,University of Kentucky.Lexington,KY 40506.USA | 2001 | World Journal of Gastroenterology2001，7，6： | 4 |
| 3 | Simultaneous multi-tear exclusion:an optimal strategy for type B thoracic aortic dissection initially proved by a single center's 8 years experience显示文摘背景 Endovascular 接枝stent 广泛地被用来对待胸的大动脉的 dissection.However ,很少信息都不关于跟随八年用为斯坦福的治疗的同时的多眼泪排除的经验打 B 胸的大动脉的解剖导致到1月2006,29日类型 B 胸的大动脉的解剖病人的从1998年9月的没有不利 events.Methods 的成功的大动脉的改变的多重 tears.This 报告细节的同时的排除的结果是可得到的( 24 个人, 5 | YUAN Liang-xi BAO Jun-min ZHAO Zhi-qing FENG Xiang OU Le-feng FENG Rui LU Qing-sheng MEI Zhi-jun JING Zai-ping Department of Vascular Surgery,Changhai Hospital,Second Military Medical University Institute of Vascular Surgery of Chinese People’s Liberation Army Clinic Center of Vascular Diseases of Shanghai National Key Department of Vascular Surgery of China Shanghai 200433,China (Yuan LX,Bao JM,Zhao ZQ,Feng X,Ou LF,Feng R,Lu QS,Mei ZJ and Jing ZP) | 2007 | Chinese Medical Journal2007，，24： | 3 |
| 4 | Adult metaplastic hutch diverticulum with robotic-assisted diverticulectomy and reconstruction:A case report显示文摘BACKGROUND Hutch diverticulum arises from the compromised muscular development at the ureteral orifice.It is a congenital disease and extremely rare in adult,only accounting for about 3%occurrence worldwide.It can be either symptomatic or asymptomatic,and relies on image tools for diagnosis and preoperative planning.Indications for surgery are dependent on the complications from the diverticulum.Metaplasia is about 10%among those with hutch diverticulum,and it still has chances turning into malignancy,especially urothelial cell carcinoma.CASE SUMMARY A 27-year-old man was presented with frequently recurrent urinary tract infection for one year,and had suffered from intermittent right flank pain for 3 mo.No past medical histories were recorded before.No obvious abnormalities on laboratory data and urine examination were found.Under ultrasound,right hydronephrosis was seen and an anatomical abnormality was observed on intravenous pyelography.Further computed tomography urogram showed one diverticulum seated at superolateral side of right ureteral orifice.Cystoscopy was done and biopsy results showed focal metaplasia.After discussing with him,roboticassisted diverticulectomy with reconstruction was performed.Right hydronephrosis was greatly improved after surgery.He has completed his 1.5-year follow-ups,and no malignancies were seen from urine cytology and image of intravenous pyelography.CONCLUSION Robotic-assisted diverticulectomy and reconstruction to hutch diverticulum is a safe and efficient operation,providing several advantages over open and laparoscopic ones. | Che H Yang Yi S Lin Yen C Ou Wei C Weng Li H Huang Chin H Lu Chao Y Hsu Min C Tung | 2020 | World Journal of Clinical Cases2020，8，20： | 2 |
| 5 | Unsteady wake over a line ar turbine blade cascade with air and CO2 film injection: part II-effect on film effect iv eness and heat transfer distribution显示文摘 | Ou S Han J C Mehendale A B | 1994 | Journal of Turbomachinery1994，116，10： | 2 |
| 6 | Rapid engineering of polyketide overproduction by gene transfer to industrially optimized strains显示文摘 | Rodriguez E Hu Z Ou S | 2003 | J Ind Microbiol Biotechnol2003，30，8： | 1 |
| 7 | Duchenne muscular dystrophy in a female patient with a karyotype of 46,X,i(X)(q10)显示文摘 | Ou Z Li S Li Q | 2010 | Tohoku J Exp Med2010，222，2： | 1 |
| 8 | The synthesis of a chiral-amino acid derivative by the Grignard reaction of an aspartic acid equivalent 显示文摘 | LIU F YU W S OU W H | 2010 | J Chem Res2010，34，9： | 1 |
| 9 | Large-scale experi- mental study of precast segmental unbonded posttensioned concrete bridge columns for seismic regions显示文摘 | OU Y C WANG P H TSAI M S | 2010 | Journal of Structural Engineering2010，136，3： | 1 |
| 10 | Crizotinib for the treatment of ALK-rearranged non-smallcell lung cancer:a success story to usher in the seconddecade of molecular targeted therapy in oncology 显示文摘 | Ou S H Bartlett C H Mino-Kenudson M | 2012 | TheOncologist2012，17，11： | 1 |
| 11 | Cryoanalgesia Electrophysiology at different temperatures显示文摘 | Zhou I Shao Z Ou S | 2003 | Cryobiology2003，46，1： | 1 |
| 12 | Changes in micro-RNA profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes显示文摘 | Ling H Y Ou H S Feng S D | | 0，，09： | 1 |
| 13 | Plasma interleukin-l~,-6,-8 and tumor necrosis factor-a as highly informative markers of pel- vic inflammatory disease 显示文摘 | Lee S A Tsai H T Ou H C | 2008 | Clin Chem Lab Med2008，46，7： | 1 |
| 14 | Role of ferulicacid in preparingediblefilms from soyproteinisolate 显示文摘 | Ou Shiyi Wang Y Tang S Z | 2005 | Jour- nal of Food Engineering2005，70，2： | 1 |
| 15 | Open reduction and in- ternal fixation of posterolateral tibial plateau fractures through fibula osteotomy-free posterolateral approach显示文摘 | Chen HW Liu G D Ou S | 2014 | Journal of Orthopaedic Trauma2014，28，9： | 1 |
| 16 | Development of new feeding-distance rules using casting simulation: part II, the new rules 显示文摘 | Ou S Carlson K D Hardin R A | 2002 | Metallurgical and Materials Transactions B2002，33，： | 1 |
| 17 | Seismic response analysis of structures with velocity-dependent dampers 显示文摘 | OU J P LONG X LI Q S | 2007 | Journal of ConstructionalSteel Research2007，63，： | 1 |
| 18 | Compact efficient diode-pumped N d:YVO4 Q-switched blue laser with intraeavity frequency tripling显示文摘 | CHEN Y F CHEN Y S OU T H | 2005 | Applied Physics B (S0946-2171)2005，81，4： | 1 |
| 19 | Ferulic acid: pharmaceutical functions prepara-tion and applications in foods显示文摘 | Ou S Y Kwok K C | 2004 | J Sci Food Agric2004，84，11： | 1 |
| 20 | Pathogen variability and host resistence in rice blast disease显示文摘 | OU S H | 1980 | Ann Rev Phystopathol1980，18，： | 1 |
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