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| 1 | 螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。 | Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，3： | 7 |
| 2 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 3 | Obstructive sleep apnea,hypertension,and their interaction on arterial stiffness and heart remodeling显示文摘 | Drager LF Bortolotto LA Figueiredo AC | 2007 | Chest2007，131，5： | 1 |
| 4 | The impact of obstruetive sleep apnea on metabolic and inflammatory markers in consecutive patients with metabolic syndrome显示文摘 | Drager LF Lopes HF Maki-Nunes C | 2010 | PloS One2010，5，12： | 1 |
| 5 | Early signs of atherosclerosis in obstructive sleep apnea 显示文摘 | Drager LF Bortolotto LA Lorenzi MC | 2005 | Am J Respir Crit Care Med2005，172，5： | 1 |
| 6 | Chronic intermittent hypoxia induces atherosclerosis via activation of adipose angiopoietin-like 4 显示文摘 | Drager LF Yao Q Hernandez KL Shin MK | 2013 | Am J Respir Crit Care Med2013，188，2： | 1 |
| 7 | Obstructive sleep apnea:an emerging risk factor for atherosclerosis显示文摘 | Drager LF Polotsky VY Lorenzi-Filho G | 2011 | Chest2011，140，2： | 1 |
| 8 | Additive effects of obstructive sleep apnea and hypertension on early markers of carotid atherosclerosis显示文摘 | Drager LF Bortolotto LA Krieger EM | 2009 | Hypertension2009，53，1： | 1 |
| 9 | Day-night pattern of autonomic nervous system modulation in patients with heart failure with and without sleep apnea 显示文摘 | Ueno LM Drager LF Rodrigues AC | 2011 | Int J Cardio12011，148，1： | 1 |
| 10 | Obstructive sleep apnea and atherosclerosis:a new paradigm 显示文摘 | Lorenzi-Filho G Drager LF | 2007 | Am J Respir Crit Care Med2007，175，12： | 1 |
| 11 | Metabolic consequences of intermittent hypoxia:relevance to obstructive sleep apnea显示文摘 | Drager LF Jun JC Polotsky VY | 2010 | Best Pract Res Clin Endocrinol Metab2010，24，5： | 1 |
| 12 | Obstructive sleep apnea:an emerging risk factor for atherosclerosis 显示文摘 | Drager LF Polotsky VY Lorenzi-Filho G | 2011 | Chest2011，140，2： | 1 |
| 13 | Obstructive sleep apnea, hypertension, and their interaction on arterial stiffness and heart remodeling显示文摘 | Drager LF Bortolotto LA Figueiredo AC | 2007 | Chest2007，131，5： | 1 |
| 14 | Cardio- vascular effects of partial sleep deprivation in healthy volunteers显示文摘 | Dettoni JL Consolim-Colombo FM Drager LF | 2012 | JApplPhysiol2012，113，2： | 1 |
| 15 | Effects of continuous positive airway pressure on early signs of atherosclerosis in obstructive sleep apnea显示文摘 | Drager LF Bortolotto LA Figueiredo AC | 2007 | Am J Respir Crit Care Med2007，176，7： | 1 |
| 16 | 经皮冠状动脉介入后阻塞性睡眠呼吸暂停与心血管事件的关系显示文摘目前关于阻塞性睡眠呼吸暂停(obstructive sleepapnea,OSA)对冠状动脉疾病患者的预后意义的大型队列研究数据匮乏。该研究假设OSA可预测行经皮冠状动脉介入治疗(percutaneous coronary intervention.PCI)患者未来主要不良心脏和脑血管事件(major adverse cardiac and cerebrovascularevents,MACCE)。方法:睡眠及支架研究是一项前瞻性、多中心注册研究,纳入2011年12月和2014年4月来自5个国家经PCI治疗成功的患者1748例。 | Lee CH Sethi R Li R Ho HH Hein T Jim MH Loo G Koo CY Gao XF Chandra S Yang XX Furlan SF Ge Z Mundhekar A Zhang WW Ucha CH Kharwar RB Chan PF Chen SL Chan MY Richards A Tan HC Ong TH Roldan G Tai BC Drager LF Zhang JJ 刘莉 叶鹏 | 2016 | 中华高血压杂志2016，24，5： | 1 |
| 17 | Obstructive sleep apnea and atheroscle- rosis: a new paradigm 显示文摘 | Lorenzi -Filho G Drager LF | 2007 | Am J Respir Crir Care Med2007，175，12： | 1 |
| 18 | Day - night pattern of autonomic nervous system modulation in patients with heart failure with and without sleep apnea 显示文摘 | Ueno LM Drager LF Rodrigues AC | 2011 | Int J Cardiol2011，148，1： | 1 |
| 19 | The incremental role of obstructive sleep apnoea on markers of atherosclerosis in patients with metabolic syndrome显示文摘 | Drager LF Bortolottoa LA Maki- Nunes C | 2010 | Atherosclerosis2010，208，2： | 1 |
| 20 | Chronic intermittent hypoxia induces atherosclerosis via activation of adipose angiopoietin-like 4显示文摘 | Drager LF Yao Q Hernandez KL | 2013 | Am J Respir Crit Care Med2013，188，2： | 1 |
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