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您的检索式：作者名="Obetien Mapudengo"
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| 1 | A 26-year clinical observation of splenic auto-transplantation and oesophageal transection anastomosis:a new treatment strategy in patients with portal hypertension显示文摘为有肝硬化和门高血压的病人的背景外科的治疗选择是复杂的。在这研究,我们评估了新治疗策略,脾的自体移植和食道的横断吻合的有效性。我们从 1979 ~ 2005 在 274 patients.Methods 从临床的观察,脾的有免疫力的功能和门动力学报导结果,有门高血压的 274 个肝硬化病人经历了新治疗策略,并且被跟随多达把结果与经历了传统的外科的治疗的那些病人作比较。从 1999 ~ 2002,使随机化的控制试用(RCT ) 在 40 个病人上被执行比较他们的手术后的有免疫力的功能。从 1994~2006 ,另一 RCT 注册了 28 个病人用三维的动态提高对比的磁性的回声 angiography ( 3D DEC MRA )比较门动力学在 274 个病人之中的调查柱子 operation.Results (意味着年龄 41.8 年),起作用的紧急情况死亡(4.4%),选择起作用的死亡(2.2%),复杂并发症率(17.9%),肝的 encephalopathy (1%)的流行,流血的门高血压胃炎( PHG )(9.1%)的率,和肝的癌(8%)的病态是 si 怒气免疫学功能(Tuftsin, IgM ) 在组减少了 2 月柱子操作,而是这减少没到达统计意义。通过 3D 数据通信设备 MRA,主要的门静脉的血流动的生气部分区域和速度和体积在两个组在操作以后显著地减少了。在自体移植组的血流动的速度和卷比在控制 group.Conclusions,脾的自体移植和食道的横断吻合是为有有 varicial 流血的门高血压的病人的安全、有效、合理的治疗策略的显著地低。它能不仅改正 hypersplenism,而且可以也完成完全的 hemostasis。直到 retroperitoneal 空间的怒气 auto-transplanted 能保存有免疫力的功能并且建立宽广并行的循环。 | Obetien Mapudengo | 2007 | Chinese Medical Journal2007，，6： | 13 |
| 2 | Splenic autotransplantation and oesophageal transection anastomosis in patients with portal hypertension (26 years clinical observation)显示文摘The surgical treatment methods for cirrhosis patients complicated with portal hypertension are complicated.In this study,we evaluated the effectiveness of a new treatment strategy:splenic auto-transplantation and oesophageal transection anastomosis on 274 patients from three aspects:clinical observation,splenic immunology and portal dynamics.From 1979 to 2005,274 cirrhosis patients with portal hypertension who underwent the new treatment strategy were followed up to observe different clinical indexes,which were then compared with those of the traditional surgery treatment.From 1999 to 2002,a randomized control trial(RCT)was performed on 40 patients to compare their immune function after operation.From 1994 to 2004,another RCT was carried out on 28 patients to compare the portal dynamics through three-dimensional dynamic contrast enhanced MR angiography(3D DEC MRA)investigation after operation.Among 274 patients(mean age 41.8 years),the emergency operative mortality(4.4%),selective operative mortality(2.2%),complication rate(17.9%),morbidity of hepatic encephalopathy(<1%),bleeding rate of portal hypertension gastritis(PHG)(9.1%),and morbidity of hepatic carcinoma(8%)were similar to those under traditional operation;the spleen immunology function(Tuftsin,IgM)decreased among the groups 2 months after operation.Through 3D DCE MRA,the cross section area,the velocity and volume of blood flow of main portal vein decrease significantly after operation in both groups,the auto transplantation group was significantly lower in velocity and volume of blood flow than in the control group.Splenic auto transplantation and esophageal transection anastomosis are a safe,effective,and reasonable treatment strategy for portal hypertension with varicial bleeding.It can not only correct hypersplenism but also completely stanch blood,and auto transplanted spleen in the retroperitoneal space can preserve immune function and establish abroad collateral circulation. | CHEN Jisheng HUO Jinshan ZHANG Hongwei SHANG Changzhen CHEN Rufu ZHANG Jie Obetien Mapudengo CHEN Yajin ZHANG Lei | 2007 | Frontiers of Medicine2007，1，1： | 0 |
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