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| 1 | Nigella sativa relieves the deleterious effects of ischemia reperfusion injury on liver显示文摘AIM: To determine whether Nigella sativa prevents hepatic ischemia-reperfusion injury to the liver. METHODS: Thirty rats were divided into three groups as sham (Group 1), control (Group 2), and Nigella sati-va (NS) treatment group (Group 3). All rats underwent hepatic ischemia for 45 min followed by 60 min period of reperfusion. Rats were intraperitoneally infused with only 0.9% saline solution in group 2. Rats in group 3 received NS (0.2 mL/kg) intraperitoneally, before isch-emia and before reperfusion. Blood samples and liver tissues were harvested from the rats, and then the rats were sacrifi ced. Serum aspartate aminotransfera-se (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels were determined. Total antioxidant capacity (TAC), catalase (CAT), total oxida-tive status (TOS), oxidative stress index (OSI) and my-eloperoxidase (MPO) in hepatic tissue were measured. Also liver tissue histopathology was evaluated by light microscopy. RESULTS: The levels of liver enzymes in group 3 weresignifi cantly lower than those in the group 2. TAC in liver tissue was significantly higher in group 3 than in group 2. TOS, OSI and MPO in hepatic tissue were signifi cantly lower in group 3 than the group 2. Histo-logical tissue damage was milder in the NS treatment group than that in the control group. CONCLUSION: Our results suggest that Nigella sa-tiva treatment protects the rat liver against to hepatic ischemia-reperfusion injury. | Fahrettin Yildiz Sacit Coban Alpaslan Terzi Mustafa Ates Nurten Aksoy Hale Cakir Ali Riza Ocak Muharrem Bitiren | 2008 | World Journal of Gastroenterology2008，14，33： | 8 |
| 2 | Autonomic Disturbances in Acute Cerebrovascular Disease显示文摘Autonomic disturbances often occur in patients with acute cerebrovascular disease due to damage of the central autonomic network. We summarize the structures of the central autonomic network and the clinical tests used to evaluate the functions of the autonomic nervous system.We review the clinical and experimental findings as well as management strategies of post-stroke autonomic disturbances including electrocardiographic changes, cardiac arrhythmias, myocardial damage, thermoregulatory dysfunction, gastrointestinal dysfunction, urinary incontinence, sexual disorders, and hyperglycemia. The occurrence of autonomic disturbances has been associated with poor outcomes in stroke patients. Autonomic nervous system modulation appears to be an emerging therapeutic strategy for stroke management in addition to treatments for sensorimotor dysfunction. | Jun Mo Lei Huang Jianhua Peng Umut Ocak Jianmin Zhang John H.Zhang | 2019 | Neuroscience Bulletin2019，35，1： | 6 |
| 3 | ltigh frequency characteristics of tin oxide thin films on Si 显示文摘 | YUKSEL O F OCAK S B SELCUK A B | 2008 | Vacuum2008，82，： | 1 |
| 4 | Discovery of new membrane-associated proteins overexpressed in small - cell lung cancer显示文摘 | Ocak S Friedman DB Chen H | 2014 | J Thorac Oncol2014，9，3： | 1 |
| 5 | Online tracking of bearing wear using wavelet packet decomposition and probabilistic modeling:a method for bearing prognostics显示文摘 | OCAK H LOPARO K A DISCENZO F M | 2007 | Journal of Sound and Vibration2007，302，45： | 1 |
| 6 | TC-99m-MIBI SPECT imaging in pa- tients with lung carcinoma: is it a functional probe of muhidrug resist- ance genes? 显示文摘 | Ak I Gulbas Z Ocak S | 2007 | J Comput Assist Tomogr2007，31，5： | 1 |
| 7 | Paraoxonase activity in glomerulonephritic patients显示文摘 | Gullulu M Kahvecioglu S Dirican M Akdag I Ocak N Demircan C | 2007 | Ren Fail2007，29，4： | 1 |
| 8 | Phthaloeyanine - based fluorescent ehemosensor for the sensing of Zn (II) in dimethyl sulfoxide - aeetonitrile 显示文摘 | Saka E T Ocak M Kantekin H | 2012 | J Incl Phenom Maeroeycl Chem2012，72，： | 1 |
| 9 | Clinical and prognostic impor tance of chromosomal abnormalities, Y chromosome microde- letions,and CFTR gene mutations in individuals with azoospermia or severe oligospermia显示文摘 | Ocak Z (Jyetiiork U Dincer MM | 2014 | Turk J Med Sci2014，44，2： | 1 |
| 10 | The effects of storage conditions on the stability of carbon monoxide in postmortem Blood 显示文摘 | Ocak A Valentour JC Blanke RV | 1985 | J Anal Toxicol1985，9，： | 1 |
| 11 | Online tracking of hearing wear using wavelet packet decomposition and proba- bilistic modeling: a method for bearing prognostics显示文摘 | OCAK H LOPARO K A DISCENZO F M | 2007 | Journal of Sound and Vibration2007，302，45： | 1 |
| 12 | Dynamic contrast-en- hanced MRI of prostate cancer at 3 T: a study of pharmacokinetic parameters 显示文摘 | Ocak I Bernardo M Metzger G | 2007 | AJR2007，189，4： | 1 |
| 13 | Modeling of a capacitive S-A MEMS accelerometer system including the noise components and verification with test result显示文摘 | Boga B Ocak I E Kulah H | | 0，，： | 1 |
| 14 | Solid-liquid interfacial energy for solid succinonitrile in equilibrium with succinonitrile dichlorobenzene eutectic liquid显示文摘 | OCAK Y AKBULUT S B(O)OY(U)K U | 2006 | Thermochimica Acta2006，445，： | 1 |
| 15 | Mortality due to pulmonary embol- ism, myocardial infarction, and stroke among incident dialysis patients 显示文摘 | Ocak G van Stralen K J Rosendaal FR | 2012 | J Thromb Haemost2012，10，12： | 1 |
| 16 | Bearing condition diagnosis and prognosis using applied nonlinear dynamical analysis of machine vibration signal 显示文摘 | Janjarasjitt S Ocak H Loparo K A | 2008 | Journal of Sound and Vibration2008，，317： | 1 |
| 17 | A medical decision support system based o: support vector machines and the genetic algorithm for th evaluation of fetal well-being 显示文摘 | OCAK H | 2013 | Journal of medica systems2013，37，2： | 1 |
| 18 | Control of Surface Settlements with Umbrella Arch Methodin Second Stage Excavations of Istanbul Metro 显示文摘 | OCAK I | | TunnelIing andUnderground Space Technology0，23，6： | 1 |
| 19 | Automatic detection of epileptic seizures in EEG using discrete wavelet transform and approximate entropy显示文摘 | Ocak H | 2009 | Expert Systems with Applications2009，36，2： | 1 |
| 20 | Automatic detection of epileptic seizures in EEG using discrete wavelet transform and approximate entropy 显示文摘 | Ocak H | 2009 | Expert Systems with Applications2009，36，： | 1 |
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